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PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
title
PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
main subject
apoptotic process
1 reference
based on heuristic
inferred from title
author
Lin Zhang
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Jian Yu
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Brian J Leibowitz
series ordinal
3
object named as
Brian Leibowitz
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
author name string
Wei Qiu
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Xinwei Wang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Wancai Yang
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
language of work or name
English
0 references
publication date
1 October 2011
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
published in
Hepatology
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
volume
54
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
page(s)
1249-1258
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
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12 July 2018
Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death
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Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis
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Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death.
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Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation
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Deletion of Puma protects hematopoietic stem cells and confers long-term survival in response to high-dose gamma-irradiation.
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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
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Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice
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12 July 2018
Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis.
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PubMed Central
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12 July 2018
PUMA, a potent killer with or without p53
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PubMed Central
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12 July 2018
JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis
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12 July 2018
PUMA suppresses intestinal tumorigenesis in mice
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PubMed Central
reference URL
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12 July 2018
PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Sp1 and p73 activate PUMA following serum starvation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Chemosensitization of head and neck cancer cells by PUMA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
The Bcl-2 apoptotic switch in cancer development and therapy
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12 July 2018
p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusion
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality.
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PubMed Central
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12 July 2018
Hepatocellular carcinoma pathogenesis: from genes to environment
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12 July 2018
Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Deletion of Bid impedes cell proliferation and hepatic carcinogenesis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Suppression of tumorigenesis by the p53 target PUMA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Focus on hepatocellular carcinoma.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Role of connexin32 and beta-catenin in tumor promotion in mouse liver
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Bcl-2 expression inhibits liver carcinogenesis and delays the development of proliferating foci
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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12 July 2018
BH3-Only proteins-essential initiators of apoptotic cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
12 July 2018
Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
12 July 2018
HBx gene of hepatitis B virus induces liver cancer in transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
12 July 2018
Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
12 July 2018
p53 mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
12 July 2018
Can loss of apoptosis protect against cancer?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
26 September 2018
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
26 September 2018
Apoptosis in stages of mouse hepatocarcinogenesis: failure to counterbalance cell proliferation and to account for strain differences in tumor susceptibility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
26 September 2018
Heterozygous p53-deficient (+/-) mice develop fewer p53-negative preneoplastic focal liver lesions in response to treatment with diethylnitrosamine than do wild-type (+/+) mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
26 September 2018
Bcl-2 delays and alters hepatic carcinogenesis induced by transforming growth factor alpha.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
retrieved
26 September 2018
Characterization of histochemically detectable altered hepatocyte foci and their relationship to hepatic tumorigenesis in rats treated once with diethylnitrosamine or benzo(a)pyrene within one day after birth.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184207
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26 September 2018
Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24516
retrieved
21 January 2018
Expressional and mutational analysis of pro-apoptotic Bcl-2 member PUMA in hepatocellular carcinomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21725994
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular pathogenesis of human hepatocellular carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21725994
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Production of a highly reactive alkylating agent from the organospecific carcinogen methylazoxymethanol by alcohol dehydrogenase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21725994
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Carcinogenicity of diethylnitrosamine in newborn, infant, and adult mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21725994
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Paradoxical inhibition of c-myc-induced carcinogenesis by Bcl-2 in transgenic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21725994
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/HEP.24516
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
PMC publication ID
3184207
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
PubMed publication ID
21725994
1 reference
stated in
Europe PubMed Central
PMC publication ID
3184207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725994%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
ResearchGate publication ID
51464214
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