(Q35072901)

6 August 2017

title

Homeostatic bioenergetic network regulation - a novel concept to avoid pharmacoresistance in epilepsy (English)

1 reference

6 August 2017

Detlev Boison

1

1 reference

ORCID Public Data File 2021

author name string

Susan A Masino

series ordinal

2

1 reference

6 August 2017

Jonathan D Geiger

series ordinal

3

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 July 2011

1 reference

Expert Opinion on Drug Discovery

6 August 2017

published in

1 reference

6 August 2017

volume

6

1 reference

6 August 2017

issue

7

1 reference

6 August 2017

page(s)

713-724

1 reference

Adenosine kinase as a target for therapeutic antisense strategies in epilepsy

6 August 2017

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8 July 2018

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8 July 2018

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Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

8 July 2018

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Delayed time to first remission identifies poor long-term drug response of childhood-onset epilepsy: a prospective population-based study.

8 July 2018

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Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: systematic review and meta-analysis

8 July 2018

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8 July 2018

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8 July 2018

Silk as a Biomaterial

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Ketogenic Diets: An Update for Child Neurologists

8 July 2018

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8 July 2018

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Intrinsic severity as a determinant of antiepileptic drug refractoriness

8 July 2018

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Several major antiepileptic drugs are substrates for human P-glycoprotein

8 July 2018

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Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group

8 July 2018

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Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum

8 July 2018

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The clinical impact of pharmacogenetics on the treatment of epilepsy

8 July 2018

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Silk polymer-based adenosine release: therapeutic potential for epilepsy

8 July 2018

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8 July 2018

How do seizures stop?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Are purines mediators of the anticonvulsant/neuroprotective effects of ketogenic diets?

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade

8 July 2018

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Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease

8 July 2018

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Methionine metabolism and liver disease

8 July 2018

1 reference

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Glia as a source of cytokines: implications for neuronal excitability and survival

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Different cellular sources and different roles of adenosine: A1 receptor-mediated inhibition through astrocytic-driven volume transmission and synapse-restricted A2A receptor-mediated facilitation of plasticity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Pharmacotherapy of epilepsy: new armamentarium, new issues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: a gene polymorphism perspective study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Drug transporters in the epileptic brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

The tripartite synapse: roles for gliotransmission in health and disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

The blood-brain barrier and epilepsy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

New-onset temporal lobe epilepsy in children: lesion on MRI predicts poor seizure outcome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Functional changes in astroglial cells in epilepsy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Transgenic overexpression of adenosine kinase aggravates cell death in ischemia.

8 July 2018

1 reference

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Status epilepticus: pathophysiology and management in adults

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Novel mechanisms underlying drug resistance in temporal lobe epilepsy.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Molecular and cellular mechanisms of pharmacoresistance in epilepsy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Adenosine receptor signaling in the brain immune system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Drug resistance in brain diseases and the role of drug efflux transporters.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Neonatal hepatic steatosis by disruption of the adenosine kinase gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

N6-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

Effect of adenosine receptor modulation on pentylenetetrazole-induced seizures in rats

8 July 2018

1 reference

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The effects of adenosine A3 receptor stimulation on seizures in mice

8 July 2018

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Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy

8 July 2018

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Astroglial metabolic networks sustain hippocampal synaptic transmission

21 January 2018

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Carbamazepine-resistance in the epileptic dentate gyrus of human hippocampal slices.

21 January 2018

1 reference

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Antiepileptic drug resistant rats differ from drug responsive rats in GABA A receptor subunit expression in a model of temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Antiepileptic drug-resistant rats differ from drug-responsive rats in hippocampal neurodegeneration and GABA(A) receptor ligand binding in a model of temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Diminished response of CA1 neurons to antiepileptic drugs in chronic epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

How to explain multidrug resistance in epilepsy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Expression and cellular distribution of multidrug resistance-related proteins in patients with focal cortical dysplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Expression of the multidrug transporter MRP2 in the blood-brain barrier after pilocarpine-induced seizures in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Multidrug resistance in epilepsy: rats with drug-resistant seizures exhibit enhanced brain expression of P-glycoprotein compared with rats with drug-responsive seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Region-specific overexpression of P-glycoprotein at the blood-brain barrier affects brain uptake of phenytoin in epileptic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

The multidrug transporter hypothesis of drug resistance in epilepsy: Proof-of-principle in a rat model of temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

The effect of a low-carbohydrate, ketogenic diet on nonalcoholic fatty liver disease: a pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Postnatal caffeine treatment affects differently two pentylenetetrazol seizure models in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Loss of astrocytic domain organization in the epileptic brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Correlations between granule cell physiology and bioenergetics in human temporal lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

The epigenetic modifier, valproic acid, enhances radiation sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Organic compound synthesis on the primitive earth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Shift of adenosine kinase expression from neurons to astrocytes during postnatal development suggests dual functionality of the enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Adenosine A1 receptors are crucial in keeping an epileptic focus localized.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Adenosine A1 and A2A receptors of hippocampal CA1 region have opposite effects on piriform cortex kindled seizures in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Adenosine A2A receptor deficient mice are partially resistant to limbic seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

2-Chloroadenosine, a preferential agonist of adenosine A1 receptors, enhances the anticonvulsant activity of carbamazepine and clonazepam in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

A prospective study of the modified Atkins diet for intractable epilepsy in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

The modified Atkins diet: a potential treatment for developing countries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2011.575777

2-Chloro-N6-cyclopentyladenosine enhances the anticonvulsant action of carbamazepine in the mouse maximal electroshock-induced seizure model.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124847

The influence of C3435T polymorphism of ABCB1 gene on penetration of phenobarbital across the blood-brain barrier in patients with generalized epilepsy

27 September 2018

1 reference

12 December 2020

Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats

1 reference

12 December 2020

Effects of adenosine receptor agonists and antagonists on audiogenic seizure-sensible DBA/2 mice

1 reference

12 December 2020

Seizure clustering during drug treatment affects seizure outcome and mortality of childhood-onset epilepsy

1 reference

12 December 2020

Early seizure frequency and aetiology predict long-term medical outcome in childhood-onset epilepsy

1 reference

12 December 2020

Differential effects of agents enhancing purinergic transmission upon the antielectroshock efficacy of carbamazepine, diphenylhydantoin, diazepam, phenobarbital, and valproate in mice

1 reference

12 December 2020

A case-control evaluation of the ketogenic diet versus ACTH for new-onset infantile spasms

1 reference

12 December 2020

10.1517/17460441.2011.575777

Identifiers

DOI

1 reference

release_no6ohswgljd2bopq3rkmapsz6i

6 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/no6ohswgljd2bopq3rkmapsz6i

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3124847

1 reference

6 August 2017

1 reference