(Q35075706)

6 August 2017

title

ESR1 amplification in breast cancer by optimized RNase FISH: frequent but low-level and heterogeneous (English)

1 reference

6 August 2017

Frederik Holst

2

0 references

Cathy B Moelans

object named as

Cathy B Moelans

series ordinal

1

0 references

Paul J van Diest

series ordinal

5

object named as

Paul J van Diest

1 reference

6 August 2017

Olaf Hellwinkel

3

1 reference

6 August 2017

Ronald Simon

series ordinal

4

1 reference

6 August 2017

language of work or name

English

0 references

publication date

18 December 2013

1 reference

6 August 2017

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6 August 2017

volume

8

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6 August 2017

issue

12

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6 August 2017

page(s)

e84189

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Creative Commons Attribution 4.0 International

6 August 2017

copyright license

start time

18 December 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Prognostic significance of ESR1 gene amplification, mRNA/protein expression and functional profiles in high-risk early breast cancer: a translational study of the Hellenic Cooperative Oncology Group (HeCOG)

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Statistical challenges associated with detecting copy number variations with next-generation sequencing.

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867473

ESR1 gene status correlates with estrogen receptor protein levels measured by ligand binding assay and immunohistochemistry

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867473

Gene amplification of ESR1 in breast cancers--fact or fiction? A fluorescence in situ hybridization and multiplex ligation-dependent probe amplification study

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867473

Repetitive DNA and next-generation sequencing: computational challenges and solutions

8 July 2018

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PTEN and PIK3CA gene copy numbers and poor outcomes in non-small cell lung cancer patients with gefitinib therapy

8 July 2018

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Prognostic and predictive role of ESR1 status for postmenopausal patients with endocrine-responsive early breast cancer in the Danish cohort of the BIG 1-98 trial

8 July 2018

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EGFR gene copy number assessment from areas with highest EGFR expression predicts response to anti-EGFR therapy in colorectal cancer

8 July 2018

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EGFR gene copy number as a predictive biomarker for patients receiving tyrosine kinase inhibitor treatment: a systematic review and meta-analysis in non-small-cell lung cancer

8 July 2018

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Somatic EGFR mutation and gene copy gain as predictive biomarkers for response to tyrosine kinase inhibitors in non-small cell lung cancer

8 July 2018

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An overview of the epidermal growth factor receptor fluorescence in situ hybridisation challenge in tumour pathology

8 July 2018

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MLPA: a rapid, reliable, and sensitive method for detection and analysis of abnormalities of 22q

8 July 2018

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Large scale copy number variation (CNV) at 14q12 is associated with the presence of genomic abnormalities in neoplasia

8 July 2018

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HER3 genomic gain and sensitivity to gefitinib in advanced non-small-cell lung cancer patients

8 July 2018

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Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

8 July 2018

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Dosage analysis of cancer predisposition genes by multiplex ligation-dependent probe amplification

8 July 2018

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THE DESTABILIZING EFFECT OF RIBONUCLEASE ON THE HELICAL DNA STRUCTURE

8 July 2018

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Tracking COL1A1 RNA in osteogenesis imperfecta. splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain

8 July 2018

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Processing of endogenous pre-mRNAs in association with SC-35 domains is gene specific

8 July 2018

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Nonrandom gene organization: structural arrangements of specific pre-mRNA transcription and splicing with SC-35 domains

8 July 2018

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ERBB-2 (HER2/neu) gene copy number, p185HER-2 overexpression, and intratumor heterogeneity in human breast cancer

8 July 2018

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8 July 2018

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Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients

8 July 2018

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Relative copy number gain of MYC in diagnostic needle biopsies is an independent prognostic factor for prostate cancer patients

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0084189

Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0084189

Reutilization of previously hybridized slides for fluorescence in situ hybridization

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0084189

Precursor RNAs harboring nonsense codons accumulate near the site of transcription

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0084189

Estrogen receptor alpha gene ESR1 amplification may predict endocrine therapy responsiveness in breast cancer patients.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0084189

Human cytogenetics: 46 chromosomes, 46 years and counting.

21 January 2018

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Genetic heterogeneity in HER2 testing may influence therapy eligibility.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0084189

Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0084189

Clinical significance of ESR1 gene copy number changes in breast cancer as measured by fluorescence in situ hybridisation.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0084189

Multiplex ligation-dependent probe amplification to detect HER2 amplification in breast cancer: new insights in optimal cut-off value.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867473

MLPAnalyzer: data analysis tool for reliable automated normalization of MLPA fragment data.

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867473

On the evidence for ESR1 amplification in breast cancer

27 September 2018

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12 December 2020

New cutpoints to identify increased HER2 copy number: analysis of a large, population-based cohort with long-term follow-up

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12 December 2020

EGFR gene copy number increase in vulvar carcinomas is linked with poor clinical outcome

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12 December 2020

[Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue]

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0084189

Identifiers

DOI

1 reference

6 August 2017

0 references

1 reference

6 August 2017

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