(Q35077451)

English

Conserved GXXXG- and S/T-like motifs in the transmembrane domains of NS4B protein are required for hepatitis C virus replication

scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Conserved GXXXG- and S/T-like motifs in the transmembrane domains of NS4B protein are required for hepatitis C virus replication (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

transmembrane protein

0 references

Hepatitis C virus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Qingxia Han

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Jason Aligo

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

David Manna

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Kerry Belton

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Sree V Chintapalli

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Yoojin Hong

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Randen L Patterson

7

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Damian B van Rossum

8

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Kouacou V Konan

9

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

0 references

publication date

20 April 2011

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Journal of Virology

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

85

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

6464-6479

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

New opportunities in anti-hepatitis C virus drug discovery: targeting NS4B.

1 reference

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8 July 2018

Consensus motif for integrin transmembrane helix association

1 reference

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Endocytic Rab proteins are required for hepatitis C virus replication complex formation

1 reference

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8 July 2018

Formation and function of hepatitis C virus replication complexes require residues in the carboxy-terminal domain of NS4B protein

1 reference

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8 July 2018

An Amphipathic -Helix at the C Terminus of Hepatitis C Virus Nonstructural Protein 4B Mediates Membrane Association

1 reference

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Compensatory mutations in NS3 and NS5A proteins enhance the virus production capability of hepatitis C reporter virus

1 reference

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8 July 2018

Interaction and conformational dynamics of membrane-spanning protein helices

1 reference

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Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations

1 reference

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8 July 2018

Hepatitis C virus NS4B carboxy terminal domain is a membrane binding domain

1 reference

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The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3.

1 reference

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Identification of a Novel Determinant for Membrane Association in Hepatitis C Virus Nonstructural Protein 4B

1 reference

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Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity.

1 reference

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The Hepatitis C Virus NS4B Protein Can trans-Complement Viral RNA Replication and Modulates Production of Infectious Virus

1 reference

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Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis

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A Genetic Interaction between Hepatitis C Virus NS4B and NS3 Is Important for RNA Replication

1 reference

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Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles

1 reference

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NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly

1 reference

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Comparative protein structure modeling using MODELLER

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Comparative protein structure modeling using Modeller

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Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

1 reference

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Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein

1 reference

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Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

1 reference

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Visualization of Double-Stranded RNA in Cells Supporting Hepatitis C Virus RNA Replication

1 reference

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The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without Ha-ras co-transfection

1 reference

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Replication of hepatitis C virus

1 reference

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Hepatitis C virus molecular clones and their replication capacity in vivo and in cell culture

1 reference

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8 July 2018

Allelic Variation in the Hepatitis C Virus NS4B Protein Dramatically Influences RNA Replication

1 reference

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GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

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Participation of Rab5, an Early Endosome Protein, in Hepatitis C Virus RNA Replication Machinery

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Transmembrane Domains of Hepatitis C Virus Envelope Glycoproteins: Residues Involved in E1E2 Heterodimerization and Involvement of These Domains in Virus Entry

1 reference

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8 July 2018

Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus

1 reference

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Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus and Host

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8 July 2018

Mutations of the Hepatitis C virus protein NS4B on either side of the ER membrane affect the efficiency of subgenomic replicons

1 reference

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Palmitoylation and Polymerization of Hepatitis C Virus NS4B Protein

1 reference

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8 July 2018

Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon

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Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes

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Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein

1 reference

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Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

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Complete replication of hepatitis C virus in cell culture

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Robust hepatitis C virus infection in vitro

1 reference

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An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication

1 reference

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A nucleotide binding motif in hepatitis C virus (HCV) NS4B mediates HCV RNA replication

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A specific interface between integrin transmembrane helices and affinity for ligand

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Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon

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Replication of hepatitis C virus RNA occurs in a membrane-bound replication complex containing nonstructural viral proteins and RNA.

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Nonstructural Protein Precursor NS4A/B from Hepatitis C Virus Alters Function and Ultrastructure of Host Secretory Apparatus

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Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic Replicons

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Topology of the Membrane-Associated Hepatitis C Virus Protein NS4B

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Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication

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Cell-free replication of the hepatitis C virus subgenomic replicon

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Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex

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Motifs of serine and threonine can drive association of transmembrane helices

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Effect of alpha interferon on the hepatitis C virus replicon

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The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein

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Unwinding of nucleic acids by HCV NS3 helicase is sensitive to the structure of the duplex

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Efficient initiation of HCV RNA replication in cell culture

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The transmembrane domains of hepatitis C virus envelope glycoproteins E1 and E2 play a major role in heterodimerization

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Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

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The transmembrane domain in viral fusion: essential role for a conserved glycine residue in vesicular stomatitis virus G protein

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Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus

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Comparative protein modeling by satisfaction of spatial restraints

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Identifiers

10.1128/JVI.02298-10

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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