Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q35077552)
Watch
English
Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
title
Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
main subject
leukemia
1 reference
based on heuristic
inferred from title
NF-κB
1 reference
based on heuristic
inferred from title
author
Jun-ichirou Yasunaga
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Frank C. Lin
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Kuan-Teh Jeang
series ordinal
4
object named as
Kuan-Teh Jeang
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
author name string
Xiongbin Lu
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
language of work or name
English
0 references
publication date
27 April 2011
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
volume
85
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
issue
13
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
page(s)
6212-6219
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
cites work
The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
A20: from ubiquitin editing to tumour suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
T-cell activation promotes tumorigenesis in inflammation-associated cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
The role of ubiquitin in NF-kappaB regulatory pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Frequent inactivation of A20 in B-cell lymphomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Kinetic analysis of human T-cell leukemia virus type 1 gene expression in cell culture and infected animals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
The HTLV-1 Tax interactome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Human immunodeficiency virus type 1 replication and regulation of APOBEC3G by peptidyl prolyl isomerase Pin1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Deubiquitylation and regulation of the immune response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
HTLV-1 Tax-induced NFkappaB activation is independent of Lys-63-linked-type polyubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Deubiquitinating enzymes as novel anticancer targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Integrating cell-signalling pathways with NF-kappaB and IKK function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
A genomic and functional inventory of deubiquitinating enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Comparative biology of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Activation of NF-kappaB by HTLV-I and implications for cell transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Ubiquitylation and cell signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Ubiquitin signalling in the NF-kappaB pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Stable ubiquitination of human T-cell leukemia virus type 1 tax is required for proteasome binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Ubiquitination of human T-cell leukemia virus type 1 tax modulates its activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Genetic and epigenetic inactivation of tax gene in adult T-cell leukemia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Pleiotropic effects of HTLV type 1 Tax protein on cellular metabolism: mitotic checkpoint abrogation and NF-kappaB activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Constitutive activation of NF-kappaB in primary adult T-cell leukemia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
8 July 2018
Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
27 September 2018
Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126525
retrieved
27 September 2018
"Tax-ing" the cancer stem cell
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21525354
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/JVI.00079-11
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PMCID
3126525
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PubMed ID
21525354
1 reference
stated in
Europe PubMed Central
PMCID
3126525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21525354%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
