(Q35078194)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

review article

1 reference

title

What is the role of alpha-linolenic acid for mammals? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

Andrew J Sinclair

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Nadia M Attar-Bashi

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

publication date

1 December 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

1113-1123

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12617463%20AND%20SRC:MED&resulttype=core&format=json

The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase

1 November 2019

cites work

1 reference

12 December 2020

Mechanisms of action of docosahexaenoic acid in the nervous system

1 reference

12 December 2020

Epidemiological evidence of relationships between dietary polyunsaturated fatty acids and mortality in the multiple risk factor intervention trial

1 reference

12 December 2020

Dietary α-linolenic acid and prostaglandin synthesis: a time course study

1 reference

12 December 2020

Association of energy and fat intake with prostate carcinoma risk: results from The Netherlands Cohort Study

1 reference

12 December 2020

Omega-3 polyunsaturated fatty acid regulation of gene expression

1 reference

12 December 2020

Efficiency of conversion of alpha-linolenic acid to long chain n-3 fatty acids in man.

1 reference

12 December 2020

Is docosahexaenoic acid necessary in infant formula? Evaluation of high linolenate diets in the neonatal rat.

1 reference

12 December 2020

Linoleic acid and alpha-linolenic acid lightens ultraviolet-induced hyperpigmentation of the skin.

1 reference

12 December 2020

Evidence for Nonessentiality of Linolenic Acid in the Diet of the Rat

1 reference

12 December 2020

Linseed and cod liver oil induce rapid growth in a 7-year-old girl with N-3- fatty acid deficiency

1 reference

12 December 2020

Omega-3 fatty acid content of the US food supply

1 reference

12 December 2020

Therapeutic effects of docosahexaenoic acid ethyl ester in patients with generalized peroxisomal disorders

1 reference

12 December 2020

Perinatal omega-3 fatty acid deficiency affects blood pressure later in life

1 reference

12 December 2020

"Small is beautiful": alpha-linolenic acid and eicosapentaenoic acid in man

1 reference

12 December 2020

Essential fatty acid metabolism in the feline: relationship between liver and brain production of long-chain polyunsaturated fatty acids

1 reference

12 December 2020

Inhibition of steroid 5α-reductase by specific aliphatic unsaturated fatty acids

1 reference

12 December 2020

Maintenance of lower proportions of (n − 6) eicosanoid precursors in phospholipids of human plasma in response to added dietary (n − 3) fatty acids

1 reference

12 December 2020

Antithromboxane activity of dietary alpha-linolenic acid: a pilot study

1 reference

12 December 2020

Brain docosahexaenoate accretion in fetal baboons: bioequivalence of dietary alpha-linolenic and docosahexaenoic acids

1 reference

12 December 2020

Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites

1 reference

12 December 2020

The effects of dietary alpha-linolenic acid compared with docosahexaenoic acid on brain, retina, liver, and heart in the guinea pig.

1 reference

12 December 2020

Changes in auditory brainstem responses in alpha-linolenic acid deficiency as a function of age in rats.

1 reference

12 December 2020

Increased alpha-linolenic acid intake increases tissue alpha-linolenic acid content and apparent oxidation with little effect on tissue docosahexaenoic acid in the guinea pig.

1 reference

12 December 2020

Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women

1 reference

12 December 2020

Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans.

1 reference

12 December 2020

Plausible explanations for effects of long chain polyunsaturated fatty acids (LCPUFA) on neonates

1 reference

12 December 2020

N-3 and N-6 fatty acids in breast adipose tissue and relative risk of breast cancer in a case-control study in Tours, France.

1 reference

12 December 2020

Prospective study of plasma fatty acids and risk of prostate cancer

1 reference

12 December 2020

Sebaceous gland secretion is a major physiologic route of vitamin E delivery to skin

1 reference

12 December 2020

Fatty acid and fatty aldehyde composition of the major brain lipids in normal human gray matter, white matter, and myelin

1 reference

12 December 2020

Effect of dietary alpha-linolenic acid on thrombotic risk factors in vegetarian men

1 reference

12 December 2020

Differential oxidation of individual dietary fatty acids in humans

1 reference

12 December 2020

Cloning, expression, and fatty acid regulation of the human delta-5 desaturase

1 reference

12 December 2020

Effect of docosahexaenoic acid on the synthesis of phosphatidylserine in rat brain in microsomes and C6 glioma cells

1 reference

12 December 2020

The association of fatty acids with prostate cancer risk

1 reference

12 December 2020

Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL.

1 reference

12 December 2020

Synthesis of linoleate and alpha-linolenate by chain elongation in the rat

1 reference

12 December 2020

Novel pathway of metabolism of alpha-linolenic acid in the guinea pig.

1 reference

12 December 2020

Critical differences between two low protein diet protocols in the programming of hypertension in the rat

1 reference

12 December 2020

Fetal baboons convert 18:3n-3 to 22:6n-3 in vivo. A stable isotope tracer study.

1 reference

12 December 2020

Carbon recycling into de novo lipogenesis is a major pathway in neonatal metabolism of linoleate and alpha-linolenate

1 reference

12 December 2020

Decrease in neuron size in docosahexaenoic acid-deficient brain

1 reference

12 December 2020

The long history of essential fatty acids but belated knowledge about linoleate deficiency per se: a paradox

1 reference

12 December 2020

Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein

1 reference

12 December 2020

Polyunsaturated fatty acids are potent neuroprotectors

1 reference

12 December 2020

A dietary factor essential for hair growth in rats

1 reference

12 December 2020

A decrease in cell size accompanies a loss of docosahexaenoate in the rat hippocampus

1 reference

12 December 2020

Membrane fatty acid modifications of PC12 cells by arachidonate or docosahexaenoate affect neurite outgrowth but not norepinephrine release

1 reference

12 December 2020

Dietary n-3 fatty acid deficiency decreases nerve growth factor content in rat hippocampus.

1 reference

12 December 2020

Effects of dietary alpha-linolenic acid on the conversion and oxidation of 13C-alpha-linolenic acid

1 reference

12 December 2020

Antisense-mediated depletion of potato leaf omega3 fatty acid desaturase lowers linolenic acid content and reduces gene activation in response to wounding

1 reference

12 December 2020

Prostatic levels of fatty acids and the histopathology of localized prostate cancer

1 reference

12 December 2020

Fatty acid transport and utilization for the developing brain

1 reference

12 December 2020

Breast-fed infants achieve a higher rate of brain and whole body docosahexaenoate accumulation than formula-fed infants not consuming dietary docosahexaenoate

1 reference

12 December 2020

The control of blepharospasm by essential fatty acids

1 reference

12 December 2020

Incorporation of radioactive polyunsaturated fatty acids into liver and brain of developing rat

1 reference

12 December 2020

Can adults adequately convert alpha-linolenic acid (18:3n-3) to eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3)?

1 reference

12 December 2020

Long chain polyunsaturated fatty acid formation in neonates: effect of gestational age and intrauterine growth

1 reference

12 December 2020

Comparative bioavailability of dietary alpha-linolenic and docosahexaenoic acids in the growing rat.

1 reference

12 December 2020

Optimizing DHA levels in piglets by lowering the linoleic acid to alpha-linolenic acid ratio.

1 reference

12 December 2020

Effect of an alpha-linolenic acid-rich diet on rat mammary tumor growth depends on the dietary oxidative status

1 reference

12 December 2020

Visual acuity and retinal function in infant monkeys fed long-chain PUFA.

1 reference

12 December 2020

Trienoic fatty acids and plant tolerance of high temperature

1 reference

12 December 2020

n-3 fatty acids in eggs from range-fed Greek chickens

1 reference

12 December 2020

Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study

1 reference

12 December 2020

Prediagnostic level of fatty acids in serum phospholipids: omega-3 and omega-6 fatty acids and the risk of prostate cancer

1 reference

12 December 2020

Long-term n-3 FA deficiency modifies peroxisome proliferator-activated receptor beta mRNA abundance in rat ocular tissues

1 reference

12 December 2020

Prevention of ischemia-induced cardiac sudden death by n-3 polyunsaturated fatty acids in dogs

1 reference

12 December 2020

Short communication: unsaturated fatty acids inhibit MP2C, a protein phosphatase 2C involved in the wound-induced MAP kinase pathway regulation

1 reference

12 December 2020

The role of docosahexaenoic acid containing phospholipids in modulating G protein-coupled signaling pathways: visual transduction

1 reference

12 December 2020

Dietary lipid profile is a determinant of tissue phospholipid fatty acid composition and rate of weight gain in rats

1 reference

12 December 2020

Prevention of fatal cardiac arrhythmias by polyunsaturated fatty acids

1 reference

12 December 2020

The influence of linseed oil diet on fatty acid pattern in phospholipids and thromboxane formation in platelets in man

1 reference

12 December 2020

Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study

1 reference

12 December 2020

Effect of alpha-linolenic acid in the human diet on linoleic acid metabolism and prostaglandin biosynthesis

1 reference

12 December 2020

Protective effects of docosahexaenoic acid in staurosporine-induced apoptosis: involvement of phosphatidylinositol-3 kinase pathway

1 reference

12 December 2020

Biomarkers of essential fatty acid consumption and risk of prostatic carcinoma

1 reference

12 December 2020

Does supplementation of diet with 'fish oil' reduce blood pressure? A meta-analysis of controlled clinical trials.

1 reference

12 December 2020

The Limitations of Whole Tissue Analysis to Define Linolenic Acid Deficiency

1 reference

12 December 2020

Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase

1 reference

12 December 2020

A prospective study of dietary fat and risk of prostate cancer

1 reference

12 December 2020

A case of human linolenic acid deficiency involving neurological abnormalities

1 reference

12 December 2020

Stress-induced factor involved in flower formation of Lemna is an alpha-ketol derivative of linolenic acid

1 reference

12 December 2020

Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients (Indo-Mediterranean Diet Heart Study): a randomised single-blind trial

1 reference

12 December 2020

Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin

1 reference

12 December 2020

Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans

1 reference

12 December 2020

THE EFFECT OF DOSE LEVEL OF ESSENTIAL FATTY ACIDS UPON FATTY ACID COMPOSITION OF THE RAT LIVER

1 reference

12 December 2020

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

1 reference

12 December 2020

Regulation of diacylglycerol kinase in rat brain membranes by docosahexaenoic acid

1 reference

12 December 2020

Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n-3 polyunsaturated fatty acids

1 reference

12 December 2020

Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay.

1 reference

12 December 2020

Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants

1 reference

12 December 2020

Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion

1 reference

12 December 2020

Essential fatty acid studies in primates linolenic acid requirements of capuchins

1 reference

12 December 2020

Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women.

1 reference

12 December 2020

Are omega 3 fatty acids essential nutrients for mammals?

1 reference

12 December 2020

Essential function of linoleic acid esterified in acylglucosylceramide and acylceramide in maintaining the epidermal water permeability barrier. Evidence from feeding studies with oleate, linoleate, arachidonate, columbinate and alpha-linolenate

1 reference

12 December 2020

Formation of isoprostane F(2)-like compounds (phytoprostanes F(1)) from alpha-linolenic acid in plants

1 reference

12 December 2020

Low alpha-linolenic acid content of adipose breast tissue is associated with an increased risk of breast cancer

1 reference

12 December 2020

Differential induction of plant volatile biosynthesis in the lima bean by early and late intermediates of the octadecanoid-signaling pathway

1 reference

12 December 2020

Dietary fat intake and prostate cancer risk: a case-control study in Spain

1 reference

12 December 2020

Visual Membranes: Specificity of Fatty Acid Precursors for the Electrical Response to Illumination

1 reference

12 December 2020

Workshop statement on the essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids.

1 reference

12 December 2020

The effect of docosahexaenoic acid on the electroretinogram of the guinea pig.

1 reference

12 December 2020

Butter-enriched diets reduce arterial prostacyclin production in rats

1 reference

12 December 2020

The role of n-3 polyunsaturated fatty acids in brain: modulation of rat brain gene expression by dietary n-3 fatty acids

1 reference

12 December 2020

n-3 fatty acid deficiency alters recovery of the rod photoresponse in rhesus monkeys

1 reference

12 December 2020

Energy, nutrient intake and prostate cancer risk: a population-based case-control study in Sweden

1 reference

12 December 2020

Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids

1 reference

12 December 2020

Dietary n‐3 (ω‐3) polyunsaturated fatty acid effects on animal tumorigenesis

1 reference

12 December 2020

Recycling of carbon into lipids synthesized de novo is a quantitatively important pathway of alpha-[U-13C]linolenate utilization in the developing rat brain.

1 reference

12 December 2020

Arterial compliance in obese subjects is improved with dietary plant n-3 fatty acid from flaxseed oil despite increased LDL oxidizability

1 reference

12 December 2020

Dietary 18:3n-3 and 22:6n-3 as sources of 22:6n-3 accretion in neonatal baboon brain and associated organs

1 reference

12 December 2020

Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid

1 reference

12 December 2020

Rats with low levels of brain docosahexaenoic acid show impaired performance in olfactory-based and spatial learning tasks

1 reference

12 December 2020

Dietary substitution with an alpha-linolenic acid-rich vegetable oil increases eicosapentaenoic acid concentrations in tissues

1 reference

12 December 2020

The essentiality of long chain n-3 fatty acids in relation to development and function of the brain and retina.

1 reference

12 December 2020

Changes in transepidermal water loss and the composition of epidermal lecithin after applications of pure fatty acid triglycerides to skin of essential fatty acid-deficient rats

1 reference

12 December 2020

Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival--4

1 reference

12 December 2020

High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice

1 reference

12 December 2020

Long-term effects of dietary alpha-linolenic acid from perilla oil on serum fatty acids composition and on the risk factors of coronary heart disease in Japanese elderly subjects.

1 reference

12 December 2020

Dietary linoleic acid influences desaturation and acylation of deuterium-labeled linoleic and linolenic acids in young adult males

1 reference

12 December 2020

Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain

1 reference

12 December 2020

Prevention of Sudden Cardiac Death by Dietary Pure ω-3 Polyunsaturated Fatty Acids in Dogs

1 reference

12 December 2020

Docosahexaenoic acid decreases phospholipase A2 activity in the neurites/nerve growth cones of PC12 cells

1 reference

12 December 2020

Polyunsaturated fatty acids in lipid bilayers: intrinsic and environmental contributions to their unique physical properties.

1 reference

12 December 2020

Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat.

1 reference

12 December 2020

Postnatal deficiency of omega-3 fatty acids in monkeys: fluid intake and urine concentration

1 reference

12 December 2020

Chemistry and metabolism of lipids in the vertebrate retina

1 reference

12 December 2020

Dietary low linolenic acid compared with docosahexaenoic acid alter synaptic plasma membrane phospholipid fatty acid composition and sodium-potassium ATPase kinetics in developing rats

1 reference

12 December 2020

Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men*.

1 reference

12 December 2020

High dietary 18:3n-3 increases the 18:3n-3 but not the 22:6n-3 content in the whole body, brain, skin, epididymal fat pads, and muscles of suckling rat pups

1 reference

12 December 2020

The alpha-linolenic acid content of green vegetables commonly available in Australia

1 reference

12 December 2020