(Q35078443)

6 August 2017

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title

Cancer pharmacogenomics: current and future applications (English)

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6 August 2017

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James W Watters

1

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6 August 2017

Howard L McLeod

series ordinal

2

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6 August 2017

language of work or name

English

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publication date

1 March 2003

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Biochimica et Biophysica Acta

6 August 2017

published in

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6 August 2017

volume

1603

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6 August 2017

issue

2

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6 August 2017

page(s)

99-111

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Pharmacogenomics: translating functional genomics into rational therapeutics

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Recommendation for caution with irinotecan, fluorouracil, and leucovorin for colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: summary findings of an independent panel

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Pharmacogenomics: the inherited basis for interindividual differences in drug response

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Pharmacogenomics: unlocking the human genome for better drug therapy

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https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Pharmacogenetics of cancer therapy: getting personal

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Polymorphism of the thiopurine S-methyltransferase gene in African-Americans

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Analysis of thiopurine methyltransferase variant alleles in childhood acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Population study of dihydropyrimidine dehydrogenase in cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Update on pharmacogenetics in cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Nomenclature for human DPYD alleles.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Diagnostic analysis, clinical importance and molecular basis of dihydropyrimidine dehydrogenase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Known variant DPYD alleles do not explain DPD deficiency in cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Role in translation of a triple tandemly repeated sequence in the 5'-untranslated region of human thymidylate synthase mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Functional Analysis and DNA Polymorphism of the Tandemly Repeated Sequences in the 5'-terminal Regulatory Region of the Human Gene for Thymidylate Synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Novel thymidylate synthase enhancer region alleles in African populations

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Length polymorphism of thymidylate synthase regulatory region in Chinese populations and evolution of the novel alleles

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Kinetic analysis of the in vitro binding of radioactive cis- and trans-dichlorodiammineplatinum(II) to DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

XPD polymorphisms: effects on DNA repair proficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Zeta, a novel class of glutathione transferases in a range of species from plants to humans

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

1 reference

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7 January 2021

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Gene expression profiling predicts clinical outcome of breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

The molecular outlook

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Bleomycin hydrolase and a genetic locus within the MHC affect risk for pulmonary fibrosis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

A genome-wide screen for asthma-associated quantitative trait loci in a mouse model of allergic asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Linkage analysis of susceptibility to ozone-induced lung inflammation in inbred mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Genetic linkage analysis of susceptibility to particle exposure in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Molecular monitoring of bleomycin-induced pulmonary fibrosis by cDNA microarray-based gene expression profiling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Experimental strategies for the genetic dissection of complex traits in animal models

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Protection from pulmonary fibrosis in leukotriene-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Impairment of bleomycin-induced lung fibrosis in CD28-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

Attenuation of lung inflammation and fibrosis in interferon-gamma-deficient mice after intratracheal bleomycin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900003-9

7 January 2021

10.1016/S0304-419X(03)00003-9

Identifiers

DOI

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6 August 2017

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