(Q35079903)

6 August 2017

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title

Smad4 transcriptional pathways and angiogenesis (English)

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Irmgard Schwarte-Waldhoff

6 August 2017

author

series ordinal

1

object named as

Irmgard Schwarte-Waldhoff

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6 August 2017

2

Wolff Schmiegel

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6 August 2017

publication date

1 January 2002

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International Journal of Gastrointestinal Cancer

6 August 2017

published in

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6 August 2017

volume

31

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6 August 2017

issue

1-3

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6 August 2017

page(s)

47-59

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

6 August 2017

cites work

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Signaling inputs converge on nuclear effectors in TGF-beta signaling

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Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

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Choriocarcinoma. Transfilter stimulation of vasoproliferation in the hamster cheek pouch. Studied by light and electron microscopy

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Loss of Dpc4 expression in colonic adenocarcinomas correlates with the presence of metastatic disease

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Somatic in vivo alterations of the JV18-1 gene at 18q21 in human lung cancers

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Induction of angiogenesis during the transition from hyperplasia to neoplasia

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Mutations of the DPC4/Smad4 gene in biliary tract carcinoma.

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TIEG proteins join the Smads as TGF-beta-regulated transcription factors that control pancreatic cell growth.

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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Genetics of adenocarcinomas of the small intestine: frequent deletions at chromosome 18q and mutations of the SMAD4 gene.

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12 December 2020

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

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12 December 2020

Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signaling

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12 December 2020

TGF-beta 1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence

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12 December 2020

A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA

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12 December 2020

Role of Ras and Mapks in TGFbeta signaling

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12 December 2020

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12 December 2020

Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells

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12 December 2020

Mechanisms of angiogenesis

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12 December 2020

Tumor angiogenesis: therapeutic implications

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12 December 2020

The Hallmarks of Cancer

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Allelotype of pancreatic adenocarcinoma using xenograft enrichment

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12 December 2020

Regulation of Smad signalling by protein associations and signalling crosstalk

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12 December 2020

Controlling TGF-beta signaling

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12 December 2020

Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

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12 December 2020

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

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12 December 2020

Overexpression of the TGFbeta-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells

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12 December 2020

Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression

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12 December 2020

TGF-beta signaling by Smad proteins

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12 December 2020

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

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12 December 2020

Mechanisms of angiogenesis and arteriogenesis

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12 December 2020

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

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12 December 2020

Tumor angiogenesis: transfilter diffusion studies in the hamster by the transparent chamber technique

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12 December 2020

DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression

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12 December 2020

Smads as transcriptional co-modulators

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12 December 2020

How tumors become angiogenic

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12 December 2020

Smad regulation in TGF-beta signal transduction

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12 December 2020

Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

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12 December 2020

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12 December 2020

Allelic loss is often the first hit in the biallelic inactivation of the p53 and DPC4 genes during pancreatic carcinogenesis

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12 December 2020

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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12 December 2020

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin

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12 December 2020

The pivotal role of VEGF in tumor angiogenesis: molecular facts and therapeutic opportunities

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12 December 2020

TGF-beta signaling in tumor suppression and cancer progression

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12 December 2020

Regulation of Smad activity

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12 December 2020

Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis

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12 December 2020

Human Smad3 and Smad4 are sequence-specific transcription activators

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12 December 2020

Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells

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12 December 2020

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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12 December 2020

Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor

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12 December 2020

TGFbeta signaling in growth control, cancer, and heritable disorders

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12 December 2020

Immunohistochemical expression of Smads 1-6 in the 15-day gestation mouse embryo: signaling by BMPs and TGF-betas

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12 December 2020

Suppressor and oncogenic roles of transforming growth factor-beta and its signaling pathways in tumorigenesis

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12 December 2020

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

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12 December 2020

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

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12 December 2020

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

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12 December 2020

c-myc is a downstream target of the Smad pathway

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12 December 2020

Genetic events and the role of TGF beta in epithelial tumour progression

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12 December 2020

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

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12 December 2020

Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis

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12 December 2020

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

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12 December 2020

Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma

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12 December 2020

Identifiers

DOI

10.1385/IJGC:31:1-3:47

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6 August 2017

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