(Q35080440)

6 August 2017

title

Longevity effect of IGF-1R(+/-) mutation depends on genetic background-specific receptor activation (English)

1 reference

6 August 2017

Jie Xu

1

1 reference

6 August 2017

Géraldine Gontier

2

1 reference

6 August 2017

Zayna Chaker

3

1 reference

6 August 2017

Philippe Lacube

4

1 reference

6 August 2017

Joëlle Dupont

5

1 reference

6 August 2017

Martin Holzenberger

6

1 reference

6 August 2017

publication date

11 September 2013

1 reference

6 August 2017

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6 August 2017

volume

13

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6 August 2017

issue

1

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6 August 2017

page(s)

19-28

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Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation

6 August 2017

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8 July 2018

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Does reduced IGF-1R signaling in Igf1r+/- mice alter aging?

8 July 2018

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High fat diet induced insulin resistance and glucose intolerance are gender-specific in IGF-1R heterozygous mice

8 July 2018

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Liver-derived IGF-I regulates mean life span in mice

8 July 2018

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8 July 2018

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Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

8 July 2018

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Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains

8 July 2018

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8 July 2018

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Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

8 July 2018

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8 July 2018

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Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels

8 July 2018

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Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

8 July 2018

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Lifespan extension in genetically modified mice

8 July 2018

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Sex differences in the expression of hepatic drug metabolizing enzymes

8 July 2018

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Association of FOXO3A variation with human longevity confirmed in German centenarians

8 July 2018

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Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism

8 July 2018

1 reference

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FOXO3A genotype is strongly associated with human longevity

8 July 2018

1 reference

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Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models.

8 July 2018

1 reference

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Functionally significant insulin-like growth factor I receptor mutations in centenarians

8 July 2018

1 reference

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Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

8 July 2018

1 reference

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Brain IRS2 signaling coordinates life span and nutrient homeostasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Mechanisms of disease: metabolic effects of growth hormone and insulin-like growth factor 1.

8 July 2018

1 reference

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Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Deficiency in type 1 insulin-like growth factor receptor in mice protects against oxygen-induced lung injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

The plasticity of aging: insights from long-lived mutants

8 July 2018

1 reference

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An efficient SNP system for mouse genome scanning and elucidating strain relationships.

8 July 2018

1 reference

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Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice

8 July 2018

1 reference

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Genetic mouse models of extended lifespan

8 July 2018

1 reference

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Extended longevity in mice lacking the insulin receptor in adipose tissue

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans

8 July 2018

1 reference

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Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Normal growth and development in the absence of hepatic insulin-like growth factor I

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Early postnatal nutrition determines somatotropic function in mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Neuronal death by oxidative stress involves activation of FOXO3 through a two-arm pathway that activates stress kinases and attenuates insulin-like growth factor I signaling.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Sexual dimorphism of rat liver gene expression: regulatory role of growth hormone revealed by deoxyribonucleic Acid microarray analysis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Responses of insulin-like growth factor (IGF)-I and IGF-binding proteins to nutritional status in peroxisome proliferator-activated receptor-alpha knockout mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Assessment of growth parameters and life span of GHR/BP gene-disrupted mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

A targeted partial invalidation of the insulin-like growth factor I receptor gene in mice causes a postnatal growth deficit

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326867

The potentiation of estrogen on insulin-like growth factor I action in MCF-7 human breast cancer cells includes cell cycle components

27 September 2018

1 reference

12 December 2020

The Snell dwarf mutation Pit1(dw) can increase life span in mice

1 reference

12 December 2020

Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain

1 reference

12 December 2020

Comment on "Brain IRS2 signaling coordinates life span and nutrient homeostasis"

1 reference

12 December 2020

Identifiers

DOI

10.1111/ACEL.12145

1 reference

release_4ennvmdxnncwbatt54gmsr6aya

6 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4ennvmdxnncwbatt54gmsr6aya

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4326867

1 reference

6 August 2017

1 reference