(Q35083817)

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Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool

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Europe PubMed Central

PubMed publication ID

6 August 2017

Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Reginald Davies

1

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6 August 2017

Arenda Schuurman

2

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6 August 2017

Colin R Barker

3

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6 August 2017

Bruce Clothier

4

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6 August 2017

Tatyana Chernova

5

1 reference

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6 August 2017

Fiona M Higginson

6

1 reference

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6 August 2017

David J Judah

7

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

David Dinsdale

8

1 reference

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6 August 2017

Richard E Edwards

9

1 reference

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6 August 2017

Peter Greaves

10

1 reference

Europe PubMed Central

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6 August 2017

Timothy W Gant

11

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6 August 2017

Andrew G Smith

12

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6 August 2017

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publication date

1 April 2005

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6 August 2017

The American Journal of Pathology

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6 August 2017

166

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6 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1041-1053

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

A statistical framework for the design of microarray experiments and effective detection of differential gene expression

1 reference

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Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

1 reference

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THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES

1 reference

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Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse

1 reference

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Bile salt transporters: molecular characterization, function, and regulation

1 reference

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Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal

1 reference

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Phenobarbital induction of drug/steroid-metabolizing enzymes and nuclear receptor CAR.

1 reference

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Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

1 reference

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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

1 reference

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Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis

1 reference

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Mammalian ABC transporters in health and disease

1 reference

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8 July 2018

Regulation of heme metabolism in rat hepatocytes and hepatocyte cell lines: delta-aminolevulinic acid synthase and heme oxygenase are regulated by different heme-dependent mechanisms

1 reference

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Gene expression and amplification in breast carcinoma cells with intrinsic and acquired doxorubicin resistance

1 reference

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8 July 2018

Erythropoietic protoporphyria. An overview with emphasis on the liver.

1 reference

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Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice

1 reference

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8 July 2018

Limited heme synthesis in porphobilinogen deaminase-deficient mice impairs transcriptional activation of specific cytochrome P450 genes by phenobarbital.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

8 July 2018

Theodore Woodward Award. Pathogenesis of biochemical abnormalities in protoporphyria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

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Reversion of hepatobiliary alterations By bone marrow transplantation in a murine model of erythropoietic protoporphyria

1 reference

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Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

1 reference

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8 July 2018

Erythropoietic protoporphyria with fatal liver failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

8 July 2018

Regulation of gene expression by reactive oxygen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

8 July 2018

Alteration of mRNA levels of delta-aminolevulinic acid synthase, ferrochelatase and heme oxygenase-1 in griseofulvin induced protoporphyria mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

8 July 2018

Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

8 July 2018

Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

8 July 2018

Cytochrome P450 and its interactions with the heme biosynthetic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

8 July 2018

The role of heme in gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

8 July 2018

Relationship between biliary lipid and protoporphyrin secretion; potential role of mdr2 P-glycoprotein in hepatobiliary organic anion transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

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Ferrochelatase structural mutant (Fechm1Pas) in the house mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

8 July 2018

Up-regulation of CYP2A5 expression by porphyrinogenic agents in mouse liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602388

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Induction of liver apolipoprotein A-IV mRNA in porphyric mice

1 reference

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Strain and sex differences in the response of mice to drugs that induce protoporphyria: role of porphyrin biosynthesis and removal

1 reference

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Characterization and accumulation of ferritin in hepatocyte nuclei of mice with iron overload

1 reference

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8 July 2018

Erythropoietic protoporphyria in the house mouse. A recessive inherited ferrochelatase deficiency with anemia, photosensitivity, and liver disease

1 reference

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Stimulation of the pathway of porphyrin synthesis in the liver of rats and mice by griseofulvin, 3,5-Diethoxycarbonyl-1,4-dihydrocollidine and related drugs: evidence for two basically different mechanisms

1 reference

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Is porphobilinogen deaminase activity a secondary control mechanism in haem biosynthesis in humans? [proceedings]

1 reference

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Feed-forward regulation of bile acid detoxification by CYP3A4: studies in humanized transgenic mice

1 reference

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Nuclear receptors constitutive androstane receptor and pregnane X receptor activate a drug-responsive enhancer of the murine 5-aminolevulinic acid synthase gene

1 reference

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Gene expression profiles associated with inflammation, fibrosis, and cholestasis in mouse liver after griseofulvin

1 reference

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Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression

1 reference

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Protection of the Cyp1a2(-/-) null mouse against uroporphyria and hepatic injury following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

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Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

1 reference

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Long-term cure of the photosensitivity of murine erythropoietic protoporphyria by preselective gene therapy

1 reference

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1 reference

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1 reference

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Long-term follow-up after liver transplantation for erythropoietic protoporphyria

1 reference

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Biliary fibrosis associated with altered bile composition in a mouse model of erythropoietic protoporphyria

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7 January 2021

Liver pathology and hepatocarcinogenesis in a long-term mouse model of erythropoietic protoporphyria

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7 January 2021

Gene Expression Profiles Associated with Inflammation Fibrosis and Cholestasis in Mouse Liver after Griseofulvin

1 reference

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7 January 2021

Studies of porphyrin synthesis in fibroblasts of patients with congenital erythropoietic porphyria and one patient with homozygous coproporphyria

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2962325-5

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Intrinsic Hepatic Phenotype Associated with the Cyp1a2 Gene as Shown by cDNA Expression Microarray Analysis of the Knockout Mouse

1 reference

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7 January 2021

Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription

1 reference

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7 January 2021

Liver injury and expression of cytochromes P450: evidence that regulation of CYP2A5 is different from that of other major xenobiotic metabolizing CYP enzymes

1 reference

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7 January 2021

Interaction of hemopexin, albumin and liver fatty acid-binding protein with protoporphyrin

1 reference

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7 January 2021

Modulation of hepatic heme-binding Z protein in mice by the porphyrogenic carcinogens griseofulvin and hexachlorobenzene

1 reference

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1 reference

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Turnover of cytochrome P-450 and cytochrome b5 hemes in griseofulvin-induced murine porphyria

1 reference

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7 January 2021

Identifiers

10.1016/S0002-9440(10)62325-5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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