(Q44526074)

English

Nuclear receptors constitutive androstane receptor and pregnane X receptor activate a drug-responsive enhancer of the murine 5-aminolevulinic acid synthase gene

scientific article published on 24 July 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Nuclear receptors constitutive androstane receptor and pregnane X receptor activate a drug-responsive enhancer of the murine 5-aminolevulinic acid synthase gene (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

aminolevulinic acid

1 reference

based on heuristic

inferred from title

author name string

David J Fraser

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Adrian Zumsteg

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Urs A Meyer

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

language of work or name

0 references

publication date

24 July 2003

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

number of pages

10

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

278

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Europe PubMed Central

PubMed publication ID

3 December 2017

41

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

39392-39401

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Drugs mediate the transcriptional activation of the 5-aminolevulinic acid synthase (ALAS1) gene via the chicken xenobiotic-sensing nuclear receptor (CXR).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

The RXR heterodimers and orphan receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Binding of ligands and activation of transcription by nuclear receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

PXR, CAR and drug metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Phenobarbital response elements of cytochrome P450 genes and nuclear receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

A conserved nuclear receptor consensus sequence (DR-4) mediates transcriptional activation of the chicken CYP2H1 gene by phenobarbital in a hepatoma cell line.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Transcriptional activation of cytochrome P450 CYP2C45 by drugs is mediated by the chicken xenobiotic receptor (CXR) interacting with a phenobarbital response enhancer unit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Mutational analysis of the CYP2B2 phenobarbital response unit and inhibitory effect of the constitutive androstane receptor on phenobarbital responsiveness

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Effects of modulators of protein phosphorylation on heme metabolism in human hepatic cells: induction of delta-aminolevulinic synthase mRNA and protein by okadaic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Regulation by heme of mitochondrial protein transport through a conserved amino acid motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Regulation of heme metabolism in rat hepatocytes and hepatocyte cell lines: delta-aminolevulinic acid synthase and heme oxygenase are regulated by different heme-dependent mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

NUBIScan, an in silico approach for prediction of nuclear receptor response elements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Use of in vitro pregnane X receptor assays to assess CYP3A4 induction potential of drug candidates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Three amino acid substitutions selectively disrupt the activation but not the repression function of the glucocorticoid receptor N terminus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Regulation of cyp3a gene transcription by the pregnane x receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Phenobarbital induction of drug/steroid-metabolizing enzymes and nuclear receptor CAR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Induction of 5-aminolevulinate synthase by drugs is independent of increased apocytochrome P450 synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306148200

21 January 2018

Identifiers

10.1074/JBC.M306148200

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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