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Regulation of thymocyte development: only the meek survive
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Regulation of thymocyte development: only the meek survive
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
main subject
thymocyte
0 references
author name string
Paul E Love
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
Andrew C Chan
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
publication date
1 April 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
volume
15
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
issue
2
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stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
page(s)
199-203
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
cites work
Different initiation of pre-TCR and gammadeltaTCR signalling
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The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte.
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Activated Ras signals differentiation and expansion of CD4+8+ thymocytes
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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Extracellular signal-regulated kinase (ERK) activation by the pre-T cell receptor in developing thymocytes in vivo.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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A nonredundant role for the adapter protein Shc in thymic T cell development
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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A LAT mutation that inhibits T cell development yet induces lymphoproliferation
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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Induction of T helper type 2 immunity by a point mutation in the LAT adaptor
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Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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Constitutive endocytosis and degradation of the pre-T cell receptor.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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Distinct structure and signaling potential of the gamma delta TCR complex
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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ITAM multiplicity and thymocyte selection: how low can you go?
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection.
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Positive and negative selection invoke distinct signaling pathways.
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Raf regulates positive selection
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
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7 January 2021
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Cytokines, virokines and the evolution of immunity
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7 January 2021
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The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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JNK is required for effector T-cell function but not for T-cell activation
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Disruption of T cell signaling networks and development by Grb2 haploid insufficiency.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Murine Schnurri-2 is required for positive selection of thymocytes
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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MEK activity regulates negative selection of immature CD4+CD8+ thymocytes.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection
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7 January 2021
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The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase
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Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
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Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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inferred from DOI database lookup
Altered thymic positive selection and intracellular signals in Cbl-deficient mice
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Cbl-b regulates the CD28 dependence of T-cell activation.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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CD4+ CD25+ suppressor T cells: more questions than answers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Policing the regulators
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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CD4+CD25+ T-cell development is regulated by at least 2 distinct mechanisms
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Blocked Ras activation in anergic CD4+ T cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
based on heuristic
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Transcriptional mechanisms underlying lymphocyte tolerance.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Protein kinase A RI beta subunit deficiency in lupus T lymphocytes: bypassing a block in RI beta translation reconstitutes protein kinase A activity and augments IL-2 production
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Abnormal T cell signal transduction in systemic lupus erythematosus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900002-5
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7 January 2021
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Identifiers
DOI
10.1016/S0952-7915(03)00002-5
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
PubMed ID
12633670
1 reference
stated in
Europe PubMed Central
PubMed ID
12633670
retrieved
6 August 2017
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