(Q35084389)

English

Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion.

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scholarly article

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Europe PubMed Central

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26 February 2020

Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion (English)

1 reference

Europe PubMed Central

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26 February 2020

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Mycobacterium tuberculosis

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Stephen A. Renshaw

15

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26 February 2020

Angeleen Fleming

16

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26 February 2020

17

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26 February 2020

Randall J Basaraba

11

object named as

Randall Basaraba

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26 February 2020

author name string

Mark Schiebler

1

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26 February 2020

Karen Brown

2

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26 February 2020

Krisztina Hegyi

3

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26 February 2020

Sandra M Newton

4

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26 February 2020

Maurizio Renna

5

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26 February 2020

Lucy Hepburn

6

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26 February 2020

Catherine Klapholz

7

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26 February 2020

Sarah Coulter

8

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26 February 2020

Andres Obregón-Henao

9

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26 February 2020

Marcela Henao Tamayo

10

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26 February 2020

Beate Kampmann

12

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26 February 2020

Katherine M Henry

13

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26 February 2020

Joseph Burgon

14

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26 February 2020

Karen E Anderson

18

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26 February 2020

Phillip T Hawkins

19

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26 February 2020

Diane J Ordway

20

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26 February 2020

David C Rubinsztein

21

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26 February 2020

Rodrigo Andres Floto

22

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26 February 2020

publication date

1 February 2015

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26 February 2020

EMBO Molecular Medicine

1 reference

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26 February 2020

7

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26 February 2020

2

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26 February 2020

127-139

1 reference

Europe PubMed Central

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26 February 2020

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

1 reference

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8 July 2018

Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway

1 reference

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8 July 2018

Global tuberculosis control: lessons learnt and future prospects

1 reference

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8 July 2018

Infection of zebrafish embryos with intracellular bacterial pathogens

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8 July 2018

Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks

1 reference

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8 July 2018

Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection.

1 reference

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8 July 2018

The evolving role of mTOR inhibition in transplantation tolerance

1 reference

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Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry.

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Glutamine triggers and potentiates glucagon-like peptide-1 secretion by raising cytosolic Ca2+ and cAMP.

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8 July 2018

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

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8 July 2018

MDR tuberculosis--critical steps for prevention and control

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8 July 2018

Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.

1 reference

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8 July 2018

Molecular model of anticonvulsant drug binding to the voltage-gated sodium channel inner pore

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8 July 2018

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8 July 2018

Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hosts

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8 July 2018

Insights into early mycobacterial pathogenesis from the zebrafish

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8 July 2018

Animal model of Mycobacterium abscessus lung infection

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8 July 2018

Phospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxis

1 reference

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8 July 2018

Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5.

1 reference

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8 July 2018

Lithium induces autophagy by inhibiting inositol monophosphatase

1 reference

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8 July 2018

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

1 reference

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8 July 2018

Lithium and bipolar mood disorder: the inositol-depletion hypothesis revisited

1 reference

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8 July 2018

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

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Ca(2+) signalling is not required for chemotaxis in Dictyostelium

1 reference

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8 July 2018

Loss of a prolyl oligopeptidase confers resistance to lithium by elevation of inositol (1,4,5) trisphosphate.

1 reference

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8 July 2018

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Regulation of presynaptic neurotransmission by macroautophagy

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27 September 2018

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components.

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27 September 2018

Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions

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Neuroprotective role of Na+/myo-inositol cotransporter against veratridine cytotoxicity

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of Human Antimycobacterial Immunity Using Recombinant Reporter Mycobacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/25535254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced macrophage activity in granulomatous lesions of immune mice challenged with Mycobacterium tuberculosis

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

The human macrophage sodium channel NaV1.5 regulates mycobacteria processing through organelle polarization and localized calcium oscillations

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.15252/EMMM.201404137

1 reference

Europe PubMed Central

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26 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25535254%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25535254%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

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