(Q35091473)

6 August 2017

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title

Apoptosis in hepatitis C virus infection (English)

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6 August 2017

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Bantel H

1

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PubMed ID

12655346

6 August 2017

Schulze-Osthoff K

series ordinal

2

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6 August 2017

1 January 2003

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Cell Death & Differentiation

6 August 2017

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6 August 2017

10 Suppl 1

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6 August 2017

S48-58

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401119

6 August 2017

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cites work

Epidemiology of hepatitis C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Differences in hypervariable region 1 quasispecies of hepatitis C virus in human serum, peripheral blood mononuclear cells, and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Detection of widespread hepatocyte infection in chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Shrinkage necrosis: a distinct mode of cellular death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Lethal effect of the anti-Fas antibody in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C viral quasispecies and liver damage in patients with chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatic Fas antigen expression before and after interferon therapy in patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Role of Fas ligand in apoptosis induced by hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Fas-mediated hepatocyte apoptosis is increased by hepatitis C virus infection and alcohol consumption, and may be associated with hepatic fibrosis: mechanisms of liver cell injury in chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Analysis of successful immune responses in persons infected with hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Determinants of viral clearance and persistence during acute hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Intrahepatic hepatitis C RNA levels do not correlate with degree of liver injury in patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Histological Damage in Chronic Hepatitis C Is Not Related to the Extent of Infection in the Liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Liver cell apoptosis in chronic hepatitis C correlates with histological but not biochemical activity or serum HCV-RNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Dynamics of intra-hepatic lymphocytes in chronic hepatitis C: enrichment for Valpha24+ T cells and rapid elimination of effector cells by apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Induction of tumor necrosis factor alpha production by human hepatocytes in chronic viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

IFN-gamma induces cell death in human hepatoma cells through a TRAIL/death receptor-mediated apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Cell nucleus and DNA fragmentation are not required for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C virus dynamics in vivo: effect of ribavirin and interferon alfa on viral turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Apoptosis signaling by death receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Fas-mediated apoptosis in mouse hepatocytes involves the processing and activation of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Opening of the mitochondrial permeability transition pore causes matrix expansion and outer membrane rupture in Fas-mediated hepatic apoptosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Host defense, viruses and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Molecular virology of the hepatitis C virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Suppression of apoptotic cell death by hepatitis C virus core protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Inhibition of tumor necrosis factor (TNF-alpha)-mediated apoptosis by hepatitis C virus core protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C virus core protein does not inhibit apoptosis in human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Sensitization to Fas-mediated apoptosis by hepatitis C virus core protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

The HCV core protein acts as a positive regulator of fas-mediated apoptosis in a human lymphoblastoid T cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C virus core protein enhances FADD-mediated apoptosis and suppresses TRADD signaling of tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Activation of p53 tumor suppressor by hepatitis C virus core protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C virus core protein represses p21WAF1/Cip1/Sid1 promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Suppression of actinomycin D-induced apoptosis by the NS3 protein of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C virus NS5A protein protects against TNF-alpha mediated apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

HCV-core protein accelerates recovery from the insensitivity of liver cells to Fas-mediated apoptosis induced by an injection of anti-Fas antibody in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Inhibition of cytochrome c release in Fas-mediated signaling pathway in transgenic mice induced to express hepatitis C viral proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Cytotoxic T cells and viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Cytotoxic T lymphocyte response and viral load in hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C virus core protein inhibits human T lymphocyte responses by a complement-dependent regulatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Binding of the Hepatitis C Virus Envelope Protein E2 to CD81 Inhibits Natural Killer Cell Functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Magnitude of activity in chronic hepatitis C is influenced by apoptosis of T cells responsible for hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Monocyte-dependent cell death of T lymphocyte subsets in chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Enhanced peripheral T-cell apoptosis in chronic hepatitis C virus infection: association with liver disease severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Fas-mediated apoptosis of peripheral blood mononuclear cells in patients with hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Induction of apoptosis in mature T cells by tumour necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Activation of intracellular signaling by hepatitis B and C viruses: C-viral core is the most potent signal inducer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Activation of nuclear factor kappaB in hepatitis C virus infection: implications for pathogenesis and hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

NF-kappaB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Nuclear factor-kappa B in the liver of patients with chronic hepatitis C: decreased RelA expression is associated with enhanced fibrosis progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Hepatitis C virus replication in mice with chimeric human livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

Alteration in mRNA levels of Fas splice variants in hepatitis C-infected liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Serum levels of soluble Fas antigen in chronic hepatitis C patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Involvement of CD95 (Apo-1/Fas) ligand expressed by rat Kupffer cells in hepatic immunoregulation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Significance of soluble TNF receptor-I in acute-type fulminant hepatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Targeting the function of mature dendritic cells by human cytomegalovirus: a multilayered viral defense strategy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

ICE inhibitor YVADcmk is a potent therapeutic agent against in vivo liver apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Detection of elevated caspase activation and early apoptosis in liver diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

In situ monitoring of caspase activation in hepatobiliary diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Parenchymal cell apoptosis as a signal for sinusoidal sequestration and transendothelial migration of neutrophils in murine models of endotoxin and Fas-antibody-induced liver injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Role of reactive oxygen intermediates in activation-induced CD95 (APO-1/Fas) ligand expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Immunoresponsiveness in chronic hepatitis C patients: correlation between tissue and serum findings

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Ectopic expression of hepatitis C virus core protein differentially regulates nuclear transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401119

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401119

1 reference

6 August 2017

1 reference

PubMed ID

12655346