(Q35093604)

6 August 2017

1 reference

title

T cell costimulatory pathways: blockade for autoimmunity (English)

1 reference

6 August 2017

Samia J Khoury

2

0 references

author name string

Nader Najafian

series ordinal

1

1 reference

PubMed ID

12662138

6 August 2017

language of work or name

English

0 references

publication date

1 April 2003

1 reference

Expert Opinion on Biological Therapy

6 August 2017

1 reference

6 August 2017

3

1 reference

6 August 2017

2

1 reference

6 August 2017

227-236

1 reference

Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases

6 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

The role of T-cell costimulatory activation pathways in transplant rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

The role of the CD28 receptor during T cell responses to antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

The B7 and CD28 receptor families

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

CTLA4-Ig: a novel immunosuppressive agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

CTLA-4: a negative regulator of autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor alpha leads to autoimmunity in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Keratinocyte expression of B7-1 in transgenic mice amplifies the primary immune response to cutaneous antigens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Elevated expression of CD80 (B7/BB1) and other accessory molecules on synovial fluid mononuclear cell subsets in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Expression of the B7/BB1 activation antigen and its ligand CD28 in T-cell-mediated skin diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Organ injury associated with extrathymic induction of immune tolerance in doubly transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

The role of CD40 in the regulation of humoral and cell-mediated immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Identification of a costimulatory molecule rapidly induced by CD40L as CD44H.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Functional responses and costimulator dependence of memory CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

ICOS co-stimulatory receptor is essential for T-cell activation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

ICOS is critical for CD40-mediated antibody class switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

ICOS is essential for effective T-helper-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Fingerprints of anergic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Potential roles of the B7 and CD28 receptor families in autoimmunity and immune evasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Treatment of murine lupus with CTLA4Ig

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Blockade of CD40-CD40 ligand pathway induces tolerance in murine contact hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Finally, CTLA4Ig graduates to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

Costimulatory blockade in patients with rheumatoid arthritis: a pilot, dose-finding, double-blind, placebo-controlled clinical trial evaluating CTLA-4Ig and LEA29Y eighty-five days after the first infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.3.2.227

21 January 2018

Identifiers

DOI

10.1517/14712598.3.2.227

1 reference

release_yglab5vlwrbbvngpwefphiljbm

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yglab5vlwrbbvngpwefphiljbm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

12662138

1 reference

PubMed ID

12662138