(Q35101108)

25255972

6 August 2017

title

Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent (English)

1 reference

6 August 2017

1 reference

0 references

3

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3 June 2020

author name string

Yun-An A Shen

1

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3 June 2020

Yan Chen

2

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3 June 2020

Sonia R Mayoral

4

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3 June 2020

Laiman Wu

5

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3 June 2020

Dies Meijer

6

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3 June 2020

Erik M Ullian

7

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3 June 2020

Jonah R Chan

8

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3 June 2020

Q Richard Lu

9

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3 June 2020

language of work or name

English

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publication date

26 September 2014

1 reference

25255972

6 August 2017

published in

Nature Communications

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3 June 2020

volume

5

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3 June 2020

page(s)

4991

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https://scigraph.springernature.com/pub.10.1038/ncomms5991

3 June 2020

exact match

0 references

cites work

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9 July 2018

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Sustained activation of ERK1/2 MAPK in oligodendrocytes and schwann cells enhances myelin growth and stimulates oligodendrocyte progenitor expansion

9 July 2018

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Arrest of myelination and reduced axon growth when Schwann cells lack mTOR.

9 July 2018

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Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein

9 July 2018

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Schwann cell spectrins modulate peripheral nerve myelination

9 July 2018

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Assessing the role of the cadherin/catenin complex at the Schwann cell-axon interface and in the initiation of myelination

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N-WASP is required for membrane wrapping and myelination by Schwann cells

9 July 2018

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Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

9 July 2018

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Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.

9 July 2018

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Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

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Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves

9 July 2018

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The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

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LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism

9 July 2018

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Constitutively active Akt induces enhanced myelination in the CNS

9 July 2018

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Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype

9 July 2018

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Protein kinase Czeta-dependent LKB1 serine 428 phosphorylation increases LKB1 nucleus export and apoptosis in endothelial cells

9 July 2018

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Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.

9 July 2018

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The PAR proteins: fundamental players in animal cell polarization

9 July 2018

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Nectin-like proteins mediate axon Schwann cell interactions along the internode and are essential for myelination

9 July 2018

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Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

9 July 2018

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Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development

9 July 2018

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A central role for Necl4 (SynCAM4) in Schwann cell-axon interaction and myelination

9 July 2018

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LKB1/STRAD promotes axon initiation during neuronal polarization.

9 July 2018

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9 July 2018

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9 July 2018

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Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization

9 July 2018

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9 July 2018

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9 July 2018

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Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina

9 July 2018

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Neuregulin-1 type III determines the ensheathment fate of axons

9 July 2018

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Polarity proteins in axon specification and synaptogenesis

9 July 2018

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Asymmetric membrane ganglioside sialidase activity specifies axonal fate.

9 July 2018

1 reference

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Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Axonal neuregulin-1 regulates myelin sheath thickness

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Polarized domains of myelinated axons.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

The polarity protein Par-3 directly interacts with p75NTR to regulate myelination

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

LET-99 opposes Galpha/GPR signaling to generate asymmetry for spindle positioning in response to PAR and MES-1/SRC-1 signaling

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Early patterning of the C. elegans embryo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334370

Retroviral inhibition of cAMP-dependent protein kinase inhibits myelination but not Schwann cell mitosis stimulated by interaction with neurons

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25255972

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

cAMP-dependent protein kinase A is required for Schwann cell growth: interactions between the cAMP and neuregulin/tyrosine kinase pathways

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25255972

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS5991

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255972%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255972%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

25255972

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255972%20AND%20SRC:MED&resulttype=core&format=json