(Q35102064)

6 August 2017

title

MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosis (English)

1 reference

BH3 interacting domain death agonist

6 August 2017

main subject

1 reference

Serine/threonine/tyrosine interacting like 1

1 reference

BCL2 associated X, apoptosis regulator

1 reference

positive regulation of intrinsic apoptotic signaling pathway

1 reference

Jeffrey P MacKeigan

12

0 references

Stephen Tait

object named as

Stephen W Tait

4

0 references

Douglas R. Green

object named as

Douglas R Green

11

0 references

author name string

Natalie M Niemi

1

1 reference

6 August 2017

Nathan J Lanning

2

1 reference

6 August 2017

Jeff A Klomp

3

1 reference

6 August 2017

Yong Xu

5

1 reference

6 August 2017

Karl J Dykema

6

1 reference

6 August 2017

Leon O Murphy

7

1 reference

6 August 2017

L Alex Gaither

8

1 reference

6 August 2017

H Eric Xu

9

1 reference

6 August 2017

Kyle A Furge

10

1 reference

6 August 2017

language of work or name

English

0 references

publication date

24 January 2011

1 reference

Molecular and Cellular Biology

6 August 2017

published in

1 reference

6 August 2017

volume

31

1 reference

6 August 2017

issue

7

1 reference

6 August 2017

page(s)

1357-1368

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6 August 2017

cites work

The BCL-2 family reunion

1 reference

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Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax

9 July 2018

1 reference

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Caspase-independent cell death: leaving the set without the final cut.

9 July 2018

1 reference

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BAX activation is initiated at a novel interaction site

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

ER stress triggers apoptosis by activating BH3-only protein Bim

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

9 July 2018

1 reference

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Mitochondrial membrane permeabilization in cell death

9 July 2018

1 reference

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Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

9 July 2018

1 reference

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9 July 2018

1 reference

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Cellular processing of platinum anticancer drugs

9 July 2018

1 reference

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The pathophysiology of mitochondrial cell death

9 July 2018

1 reference

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Microtubule-targeted anticancer agents and apoptosis

9 July 2018

1 reference

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FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

9 July 2018

1 reference

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

9 July 2018

1 reference

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

9 July 2018

1 reference

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9 July 2018

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Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells

9 July 2018

1 reference

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

The Mitochondrial F0F1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

9 July 2018

1 reference

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Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

Abrogation of mitochondrial cytochrome c release and caspase-3 activation in acquired multidrug resistance

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135289

MEK inhibition enhances paclitaxel-induced tumor apoptosis

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21262771

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An in vitro assay to study regulated mRNA stability

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21262771

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.00788-10

1 reference

6 August 2017

1 reference

6 August 2017

1 reference