(Q35109329)

6 August 2017

title

Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin (English)

1 reference

6 August 2017

Daniel Ricklin

3

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Wilfred van der Donk

object named as

Wilfred A van der Donk

6

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John D. Lambris

object named as

John D Lambris

7

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author name string

Patrick J Knerr

1

1 reference

6 August 2017

Apostolia Tzekou

2

1 reference

6 August 2017

Hongchang Qu

4

1 reference

6 August 2017

Hui Chen

5

1 reference

6 August 2017

publication date

23 May 2011

1 reference

6 August 2017

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6 August 2017

volume

6

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6 August 2017

issue

7

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6 August 2017

page(s)

753-760

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Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency

6 August 2017

cites work

1 reference

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9 July 2018

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9 July 2018

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9 July 2018

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Structure-kinetic relationship analysis of the therapeutic complement inhibitor compstatin

9 July 2018

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9 July 2018

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Organization of the genes encoding the biosynthesis of actagardine and engineering of a variant generation system

9 July 2018

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9 July 2018

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Oxidation of lanthionines renders the lantibiotic nisin inactive.

9 July 2018

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Compstatin: a complement inhibitor on its way to clinical application

9 July 2018

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9 July 2018

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Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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The oxidative environment and protein damage.

9 July 2018

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Conus venoms: a rich source of novel ion channel-targeted peptides

9 July 2018

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Defensins: antimicrobial peptides of innate immunity

9 July 2018

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Chemical syntheses and biological activities of lactam analogues of alpha-conotoxin SI.

9 July 2018

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Native disulfide bond formation in proteins

9 July 2018

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Binding kinetics, structure-activity relationship, and biotransformation of the complement inhibitor compstatin

9 July 2018

1 reference

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Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability

9 July 2018

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Lanthionine-somatostatin analogs: synthesis, characterization, biological activity, and enzymatic stability studies.

9 July 2018

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Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

The essential function of protein-disulfide isomerase is to unscramble non-native disulfide bonds.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Design and synthesis of a specific endothelin 1 antagonist: effects on pulmonary vasoconstriction

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

To protect peptide pharmaceuticals against peptidases

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.

27 September 2018

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Synthesis of the lantibiotic lactocin S using peptide cyclizations on solid phase

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Solid-supported synthesis and biological evaluation of the lantibiotic peptide bis(desmethyl) lacticin 3147 A2.

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Compstatin inhibits complement activation by binding to the beta-chain of complement factor 3.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Analyzing a kinetic titration series using affinity biosensors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Synthesis of oxytocin analogues with replacement of sulfur by carbon gives potent antagonists with increased stability

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Orthogonally protected lanthionines: synthesis and use for the solid-phase synthesis of an analogue of nisin ring C.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Design and NMR characterization of active analogues of compstatin containing non-natural amino acids

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Interference of plasmatic reduced glutathione and hemolysis on glutathione disulfide levels in human blood.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Synthesis and biological activities of cyclic lanthionine enkephalin analogues: delta-opioid receptor selective ligands

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Kinetics and Equilibria of the Thiol/Disulfide Exchange Reactions of Somatostatin with Glutathione

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Kinetic analysis of the interactions of complement receptor 2 (CR2, CD21) with its ligands C3d, iC3b, and the EBV glycoprotein gp350/220.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Quantification of reduced and oxidized glutathione in whole blood samples by capillary electrophoresis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137721

Hydrophobic Effect and Hydrogen Bonds Account for the Improved Activity of a Complement Inhibitor, Compstatin

27 September 2018

1 reference

12 December 2020

Biomimetic stereoselective formation of methyllanthionine

1 reference

12 December 2020

Biomimetic synthesis of lantibiotics

1 reference

12 December 2020

Controlled synthesis of (S,S)-2,7-diaminosuberic acid: a method for regioselective construction of dicarba analogues of multicystine-containing peptides

1 reference

12 December 2020

Antimicrobial Leucocin Analogues with a Disulfide Bridge Replaced by a Carbocycle or by Noncovalent Interactions of Allyl Glycine Residues

1 reference

12 December 2020

Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog

1 reference

12 December 2020

Deal watch: Alcon licenses complement pathway inhibitor for macular degeneration

1 reference

12 December 2020

Cyclic thioether peptide mimetics as VCAM-VLA-4 antagonists

1 reference

12 December 2020

Identifiers

DOI

10.1021/CB2000378

1 reference

6 August 2017

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6 August 2017

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