(Q35111620)

6 August 2017

title

Identifying Small Molecules which Inhibit Autophagy: a Phenotypic Screen Using Image-Based High-Content Cell Analysis (English)

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6 August 2017

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J V Peppard

1

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6 August 2017

C Rugg

2

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6 August 2017

M Smicker

3

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6 August 2017

C Dureuil

4

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6 August 2017

B Ronan

5

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6 August 2017

O Flamand

6

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6 August 2017

L Durand

7

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6 August 2017

B Pasquier

8

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6 August 2017

publication date

7 February 2014

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Current Chemical Genomics and Translational Medicine

6 August 2017

published in

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6 August 2017

volume

8

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6 August 2017

issue

Suppl 1

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6 August 2017

page(s)

3-15

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ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

6 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

The why and how of phenotypic small-molecule screens

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

Autophagy in human health and disease

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

Autophagy modulation as a potential therapeutic target for diverse diseases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

Identifying mechanism-of-action targets for drugs and probes.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

Canonical and non-canonical autophagy: variations on a common theme of self-eating?

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

How were new medicines discovered?

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

Open innovation for phenotypic drug discovery: The PD2 assay panel

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

Methods in mammalian autophagy research

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

How many drug targets are there?

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941084

10.2174/2213988501408010003

9 July 2018

Identifiers

DOI

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6 August 2017

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6 August 2017

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