(Q35115047)

English

Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages

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Europe PubMed Central

PubMed publication ID

6 August 2017

Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Richard M Ransohoff

7

object named as

Richard M Ransohoff

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Dustin J Donnelly

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Erin E Longbrake

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Todd M Shawler

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Kristina A Kigerl

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Wenmin Lai

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

C Amy Tovar

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Phillip G Popovich

8

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

0 references

publication date

1 July 2011

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

31

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

27

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

9910-9922

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway.

1 reference

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9 July 2018

Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury

1 reference

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9 July 2018

The neuro-immune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines

1 reference

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9 July 2018

The multiple roles of monocyte subsets in steady state and inflammation

1 reference

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9 July 2018

Crucial involvement of the CX3CR1-CX3CL1 axis in dextran sulfate sodium-mediated acute colitis in mice

1 reference

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9 July 2018

The LTB4-BLT1 axis mediates neutrophil infiltration and secondary injury in experimental spinal cord injury

1 reference

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9 July 2018

Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord

1 reference

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9 July 2018

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

1 reference

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9 July 2018

Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice

1 reference

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9 July 2018

Genetic diversity of CX3CR1 gene and coronary artery disease: new insights through a meta-analysis.

1 reference

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9 July 2018

An efficient and reproducible method for quantifying macrophages in different experimental models of central nervous system pathology

1 reference

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9 July 2018

Microglial physiology: unique stimuli, specialized responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Blood monocytes: development, heterogeneity, and relationship with dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Characterization and modeling of monocyte-derived macrophages after spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Control of microglial neurotoxicity by the fractalkine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

The many roles of chemokines and chemokine receptors in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Role of fractalkine (CX3CL1) in regulating neuron-microglia interactions: development of viral-based CX3CR1 antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Antagonist of fractalkine (CX3CL1) delays the initiation and ameliorates the progression of lupus nephritis in MRL/lpr mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Viral macrophage inflammatory protein-II and fractalkine (CX3CL1) chimeras identify molecular determinants of affinity, efficacy, and selectivity at CX3CR1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Blood monocytes consist of two principal subsets with distinct migratory properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Experimental autoimmune encephalomyelitis (EAE) in CCR2(-/-) mice: susceptibility in multiple strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Expression of fractalkine and its receptor, CX3CR1, in response to ischaemia-reperfusion brain injury in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

The extra domain A of fibronectin activates Toll-like receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Functional expression of the fractalkine (CX3C) receptor and its regulation by lipopolysaccharide in rat microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Phylogenetic perspectives in innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

9 July 2018

Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Damage control in the nervous system: beware the immune system in spinal cord injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

An engineered CX3CR1 antagonist endowed with anti-inflammatory activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Monocyte subtypes predict clinical course and prognosis in human stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Gene expression profiling in anti-CD11d mAb-treated spinal cord-injured rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Polymorphism in the microglial cell-mobilizing CX3CR1 gene is associated with survival in patients with glioblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Nicotine attenuates iNOS expression and contributes to neuroprotection in a compressive model of spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Upregulated expression of toll-like receptor 4 in monocytes correlates with severity of acute cerebral infarction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Decreased expression of the fractalkine receptor CX3CR1 on circulating monocytes as new feature of sepsis-induced immunosuppression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Modulation of nitric oxide homeostasis in a mouse model of spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Inhibition of fractalkine ameliorates murine collagen-induced arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Production and neuroprotective functions of fractalkine in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Bone marrow chimeric rats reveal the unique distribution of resident and recruited macrophages in the contused rat spinal cord.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

27 September 2018

Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C hi and Ly6C lo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139517

16 November 2018

Traumatic spinal cord injury produced by controlled contusion in mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/21734283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/21734283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved functional outcome after spinal cord injury in iNOS-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21734283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD16+ monocytes produce IL-6, CCL2, and matrix metalloproteinase-9 upon interaction with CX3CL1-expressing endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21734283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21734283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fractalkine receptor (CX3CR1) inhibition is protective against ischemic acute renal failure in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21734283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21734283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential involvement of CX3CR1-mediated signals in the bactericidal host defense during septic peritonitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21734283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different role of serum components and cytokines on alveolar macrophage activation by soluble fungal (1-->3)-beta-D-glucan

1 reference

https://pubmed.ncbi.nlm.nih.gov/21734283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2114-11.2011

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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