(Q35119665)

6 August 2017

1 reference

title

Apoptosis in heart: basic mechanisms and implications in cardiovascular diseases (English)

1 reference

6 August 2017

cardiovascular disease

1 reference

1 reference

1 reference

https://api.crossref.org/works/10.1016/S1471-4914(03)00025-X

29 December 2023

author name string

Seigo Izumo

2

1 reference

6 August 2017

Peter M. Kang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12727144

29 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12727144

29 December 2023

publication date

1 April 2003

1 reference

full work available at URL

6 August 2017

https://api.elsevier.com/content/article/PII:S147149140300025X?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S1471-4914(03)00025-X

https://api.elsevier.com/content/article/PII:S147149140300025X?httpAccept=text/plain

29 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1471-4914(03)00025-X

Trends in Molecular Medicine

29 December 2023

published in

1 reference

6 August 2017

9

1 reference

6 August 2017

177-182

1 reference

6 August 2017

4

1 reference

"Apoptotic" myocytes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation: analysis by immunogold electron microscopy combined with In situ nick end-labeling

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Apoptotic versus autophagic cell death in heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Autophagy as a regulated pathway of cellular degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Apoptosis and heart failure: A critical review of the literature

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Reperfusion injury induces apoptosis in rabbit cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Caspase knockouts: matters of life and death.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Characterization of XIAP-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived H9c2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Phosphorylation by protein kinase CK2: a signaling switch for the caspase-inhibiting protein ARC

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Blocking caspase-activated apoptosis improves contractility in failing myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

From bench to clinic with apoptosis-based therapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Toward antiapoptosis as a new treatment modality

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Upregulation of the Bcl-2 family of proteins in end stage heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Apoptosis by death factor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Proinflammatory consequences of transgenic fas ligand expression in the heart

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Apoptosis of cardiac myocytes in Gsalpha transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Insulin prevents cardiomyocytes from oxidative stress-induced apoptosis through activation of PI3 kinase/Akt

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Novel role for JNK as a stress-activated Bcl2 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

beta-Adrenergic pathway induces apoptosis through calcineurin activation in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Suppression or induction of apoptosis by opposing pathways downstream from calcium-activated calcineurin

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Calcineurin is activated in rat hearts with physiological left ventricular hypertrophy induced by voluntary exercise training

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900025-X

7 January 2021

Ischemic preconditioning reduces apoptosis by upregulating anti-death gene Bcl-2

23

1 reference

https://api.crossref.org/works/10.1016/S1471-4914(03)00025-X

Myocardial gene expression of regulators of myocyte apoptosis and myocyte calcium homeostasis during hemodynamic unloading by ventricular assist devices in patients with end-stage heart failure

29 December 2023

24

1 reference

https://api.crossref.org/works/10.1016/S1471-4914(03)00025-X

29 December 2023

Identifiers

1 reference

6 August 2017

1 reference