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Pharmacogenomics of ABC transporters and its role in cancer chemotherapy.
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scholarly article
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stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Pharmacogenomics of ABC transporters and its role in cancer chemotherapy
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
chemotherapy
1 reference
based on heuristic
inferred from title
pharmacogenomics
1 reference
based on heuristic
inferred from title
author
Romano Danesi
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
Juliana Chan
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
William D Figg
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
Alex Sparreboom
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
Yukio Ando
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
publication date
1 April 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Drug Resistance Updates
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
6
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
71-84
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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7 January 2021
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Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy
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Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
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7 January 2021
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1 reference
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Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients
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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
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Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution.
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A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance
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Pharmacogenetic determinants of anti-cancer drug activity and toxicity.
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7 January 2021
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Pharmacogenetics of anticancer drug sensitivity in non-small cell lung cancer
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7 January 2021
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Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR.
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7 January 2021
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A multidrug resistance transporter from human MCF-7 breast cancer cells
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7 January 2021
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MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine
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7 January 2021
based on heuristic
inferred from DOI database lookup
St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4
1 reference
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
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Pharmacogenomics--drug disposition, drug targets, and side effects
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
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inferred from DOI database lookup
Dosing strategies for anticancer drugs: the good, the bad and body-surface area
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
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Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study
1 reference
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
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The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans
1 reference
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7 January 2021
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The effect of rifampin treatment on intestinal expression of human MRP transporters
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7 January 2021
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Evaluation of accelerator mass spectrometry in a human mass balance and pharmacokinetic study-experience with 14C-labeled (R)-6-[amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a far
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7 January 2021
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inferred from DOI database lookup
MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males
1 reference
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Crossref
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7 January 2021
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Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies
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7 January 2021
based on heuristic
inferred from DOI database lookup
C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation
1 reference
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Multidrug resistance in cancer: role of ATP-dependent transporters
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7 January 2021
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The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
1 reference
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Crossref
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7 January 2021
based on heuristic
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The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
1 reference
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7 January 2021
based on heuristic
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Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
1 reference
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7 January 2021
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Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan
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7 January 2021
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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.
1 reference
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7 January 2021
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Modulation of irinotecan metabolism by ketoconazole
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7 January 2021
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Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
A common Dubin-Johnson syndrome mutation impairs protein maturation and transport activity of MRP2 (ABCC2).
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes
1 reference
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7 January 2021
based on heuristic
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Identification of functionally variant MDR1 alleles among European Americans and African Americans
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.
1 reference
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of P-glycoprotein in pharmacokinetics: clinical implications
1 reference
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.
1 reference
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement
1 reference
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Oral delivery of taxanes
1 reference
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacology of topoisomerase I inhibitors irinotecan (CPT-11) and topotecan
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
C3435T mutation in exon 26 of the human MDR1 gene and cyclosporine pharmacokinetics in healthy subjects.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Complementary and alternative medicine: opportunities and challenges for cancer management and research
1 reference
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https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2).
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency of C3435T polymorphism of MDR1 gene in African people
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of oral bioavailability of anticancer drugs: from mouse to man.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic polymorphisms of the human MDR1 drug transporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptibility to renal epithelial tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Does P-glycoprotein play a role in anticancer drug pharmacokinetics?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dipyridamole enhances digoxin bioavailability via P-glycoprotein inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inheritance and drug response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Case-control association studies in pharmacogenetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900005-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1368-7646(03)00005-0
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
Fatcat ID
release_6f5wdsw32vdelep7wng4oukk6a
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/6f5wdsw32vdelep7wng4oukk6a
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PubMed ID
12729805
1 reference
stated in
Europe PubMed Central
PubMed ID
12729805
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729805%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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