(Q35123227)

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IL-2R common gamma-chain is epigenetically silenced by nucleophosphin-anaplastic lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK.

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

IL-2R common gamma-chain is epigenetically silenced by nucleophosphin-anaplastic lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK. (English)

1 reference

Europe PubMed Central

6 August 2017

Mariusz A Wasik

6

object named as

Mariusz Wasik

1 reference

Europe PubMed Central

6 August 2017

author name string

Qian Zhang

1

1 reference

Europe PubMed Central

6 August 2017

Hong Yi Wang

2

1 reference

Europe PubMed Central

6 August 2017

Xiaobin Liu

3

1 reference

Europe PubMed Central

6 August 2017

Gauri Bhutani

4

1 reference

Europe PubMed Central

6 August 2017

Kanchan Kantekure

5

1 reference

Europe PubMed Central

6 August 2017

language of work or name

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publication date

29 June 2011

1 reference

Europe PubMed Central

6 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

6 August 2017

108

1 reference

Europe PubMed Central

6 August 2017

11977-11982

1 reference

Europe PubMed Central

6 August 2017

29

1 reference

Europe PubMed Central

6 August 2017

Epigenetic opportunities and challenges in cancer

1 reference

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NPM-ALK oncogenic tyrosine kinase controls T-cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells

1 reference

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ALK mutants in the kinase domain exhibit altered kinase activity and differential sensitivity to small molecule ALK inhibitors

1 reference

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Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1).

1 reference

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STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression

1 reference

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MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

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Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy

1 reference

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The epigenomics of cancer

1 reference

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Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.

1 reference

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28 July 2018

STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141982

28 July 2018

Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3

1 reference

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Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells

1 reference

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Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3.

1 reference

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Chronic myeloid leukemia: a model for oncology

1 reference

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28 July 2018

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes

1 reference

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DNA methylation and the expanding epigenetics of T cell lineage commitment

1 reference

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Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

1 reference

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Retrovirus-mediated gene transfer of NPM-ALK causes lymphoid malignancy in mice.

1 reference

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ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

1 reference

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1 reference

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Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

1 reference

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Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

1 reference

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Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches.

1 reference

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21 January 2018

Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

1 reference

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21 January 2018

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1 reference

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21 January 2018

SHP1 tyrosine phosphatase negatively regulates NPM-ALK tyrosine kinase signaling

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1100319108

21 January 2018

Regulation of transcription of the Dnmt1 gene by Sp1 and Sp3 zinc finger proteins

1 reference

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21 January 2018

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

1 reference

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21 January 2018

Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells

1 reference

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21 January 2018

Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3

1 reference

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27 September 2018

Identifiers

10.1073/PNAS.1100319108

1 reference

Europe PubMed Central

6 August 2017

2011PNAS..10811977Z

0 references

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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