(Q35123882)

6 August 2017

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title

Defective neurofilament transport in mouse models of amyotrophic lateral sclerosis: a review (English)

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amyotrophic lateral sclerosis

6 August 2017

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author name string

Mala V Rao

series ordinal

1

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PubMed ID

12737529

6 August 2017

Ralph A Nixon

series ordinal

2

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6 August 2017

1 July 2003

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6 August 2017

Neurochemical Research

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6 August 2017

28

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6 August 2017

1041-1047

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6 August 2017

7

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https://scigraph.springernature.com/pub.10.1023/a:1023259207015

6 August 2017

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cites work

Regional modulation of neurofilament organization by myelination in normal axons

1 reference

12 December 2020

Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin

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12 December 2020

Subunit composition of neurofilaments specifies axonal diameter.

1 reference

12 December 2020

Identification of Ser-55 as a major protein kinase A phosphorylation site on the 70-kDa subunit of neurofilaments. Early turnover during axonal transport

1 reference

12 December 2020

Rapid movements of vimentin on microtubule tracks: kinesin-dependent assembly of intermediate filament networks

1 reference

12 December 2020

Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease

1 reference

12 December 2020

The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons

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12 December 2020

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

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12 December 2020

Fast transport of neurofilament protein along microtubules in squid axoplasm

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12 December 2020

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12 December 2020

Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits

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12 December 2020

Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation

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12 December 2020

Mechanisms of Fast and Slow Axonal Transport

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12 December 2020

Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation

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12 December 2020

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

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12 December 2020

In vitro evidence that covalent crosslinking of neurofilaments occurs in gamma-diketone neuropathy

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12 December 2020

Neurofilaments consist of distinct populations that can be distinguished by C-terminal phosphorylation, bundling, and axonal transport rate in growing axonal neurites.

1 reference

12 December 2020

Increasing neurofilament subunit NF-M expression reduces axonal NF-H, inhibits radial growth, and results in neurofilamentous accumulation in motor neurons.

1 reference

12 December 2020

Neurofilament phosphorylation: a new look at regulation and function

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12 December 2020

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

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12 December 2020

Axonal transport of neurofilaments in normal and disease states

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12 December 2020

Slow axonal transport: the subunit transport model

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12 December 2020

Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells

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12 December 2020

A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease

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12 December 2020

The polypeptide composition of intra-axonally transported proteins: evidence for four transport velocities

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12 December 2020

Hypophosphorylated neurofilament subunits undergo axonal transport more rapidly than more extensively phosphorylated subunits in situ

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12 December 2020

Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons.

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12 December 2020

The intermediate filament protein peripherin is the specific interaction partner of mouse BPAG1-n (dystonin) in neurons

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12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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12 December 2020

Human synemin gene generates splice variants encoding two distinct intermediate filament proteins

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12 December 2020

Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M.

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12 December 2020

Axonal transport of actin in rabbit retinal ganglion cells

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12 December 2020

Neurofilaments are obligate heteropolymers in vivo

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12 December 2020

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

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12 December 2020

Aluminum alters the electrophoretic properties of neurofilament proteins: role of phosphorylation state.

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12 December 2020

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

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12 December 2020

Slow axonal transport: fast motors in the slow lane.

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12 December 2020

Oligodendroglia regulate the regional expansion of axon caliber and local accumulation of neurofilaments during development independently of myelin formation

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12 December 2020

A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene

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12 December 2020

Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits

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12 December 2020

Neuropathological abnormalities in transgenic mice harbouring a phosphorylation mutant neurofilament transgene.

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12 December 2020

Visualization of slow axonal transport in vivo.

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12 December 2020

Rapid movement of axonal neurofilaments interrupted by prolonged pauses

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12 December 2020

Slow components of axonal transport: two cytoskeletal networks

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12 December 2020

Protein incorporation and axoplasmic flow in motoneuron fibres following intra-cord injection of labelled leucine

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12 December 2020

Selective impairment of fast anterograde axonal transport in the peripheral nerves of asymptomatic transgenic mice with a G93A mutant SOD1 gene.

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12 December 2020

Neurofilaments in health and disease

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12 December 2020

Slow Axonal Transport of Neurofilament Proteins: Impairment of β,β′-Iminodipropionitrile Administration

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12 December 2020

Overexpression of neurofilament subunit M accelerates axonal transport of neurofilaments

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12 December 2020

C-terminal phosphorylation of the high molecular weight neurofilament subunit correlates with decreased neurofilament axonal transport velocity

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12 December 2020

Disruption of the NF-H gene increases axonal microtubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta,beta'-iminodipropionitrile

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12 December 2020

Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis

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12 December 2020

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

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12 December 2020

Molecular and cellular biology of intermediate filaments

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12 December 2020

Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.

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12 December 2020

Extra neurofilament NF-L subunits rescue motor neuron disease caused by overexpression of the human NF-H gene in mice.

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12 December 2020

Neurofilaments run sprints not marathons

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12 December 2020

Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton

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12 December 2020

Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments

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12 December 2020

Neurofilaments are transported rapidly but intermittently in axons: implications for slow axonal transport.

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12 December 2020

Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: characterization and evidence for their differential association with stationary and moving neurofilaments

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12 December 2020

Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis

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12 December 2020

Activation of mitogen-activated protein kinases (Erk1 and Erk2) cascade results in phosphorylation of NF-M tail domains in transfected NIH 3T3 cells

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12 December 2020

Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis

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12 December 2020

Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport

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12 December 2020

Altered slow axonal transport and regeneration in a myelin-deficient mutant mouse: the trembler as an in vivo model for Schwann cell-axon interactions

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12 December 2020

Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber

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12 December 2020

Glutamate slows axonal transport of neurofilaments in transfected neurons

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12 December 2020

Multiple fates of newly synthesized neurofilament proteins: evidence for a stationary neurofilament network distributed nonuniformly along axons of retinal ganglion cell neurons

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12 December 2020

Multiple phosphorylation sites in mammalian neurofilament polypeptides.

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12 December 2020

Expression of NF-L in both neuronal and nonneuronal cells of transgenic mice: increased neurofilament density in axons without affecting caliber

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12 December 2020

Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice.

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12 December 2020

Slow axonal transport of neurofilament protein in cultured neurons.

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12 December 2020

Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis

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12 December 2020

Late onset of motor neurons in mice overexpressing wild-type peripherin

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12 December 2020

Integrators of the cytoskeleton that stabilize microtubules

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12 December 2020

Axonal transport of actin: Slow component b is the principal source of actin for the axon

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12 December 2020

Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content

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12 December 2020

The riddle of slow transport - an introduction.

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12 December 2020

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

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12 December 2020

Local control of neurofilament accumulation during radial growth of myelinating axons in vivo. Selective role of site-specific phosphorylation

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12 December 2020

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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12 December 2020

Nerve-specific enolase and creatine phosphokinase in axonal transport: soluble proteins and the axoplasmic matrix

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12 December 2020

The identification of two intra-axonally transported polypeptides resembling myosin in some respects in the rabbit visual system

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12 December 2020

CDK-5-mediated neurofilament phosphorylation in SHSY5Y human neuroblastoma cells

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12 December 2020

Temporal and spatial variations in slow axonal transport velocity along peripheral motoneuron axons

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12 December 2020

Kinesin-mediated transport of neurofilament protein oligomers in growing axons

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12 December 2020

Clathrin is axonally transported as part of slow component b: the microfilament complex

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12 December 2020

Slow axonal transport: the polymer transport model.

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12 December 2020

Dynamic behavior and organization of cytoskeletal proteins in neurons: reconciling old and new findings

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12 December 2020

Aluminum intoxication: a disorder of neurofilament transport in motor neurons

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12 December 2020

An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1023259207015

1 reference

PubMed ID

12737529

Dimensions Publication ID

6 August 2017

0 references

1 reference

PubMed ID

12737529