(Q35125834)

6 August 2017

title

Virus-like particles activate type I interferon pathways to facilitate post-exposure protection against Ebola virus infection (English)

1 reference

6 August 2017

main subject

Orthoebolavirus zairense

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5

Sina Bavari

1 reference

6 August 2017

Scott M Anthony

3

1 reference

ORCID Public Data File 2021

Steven B Bradfute

series ordinal

2

object named as

Steven B Bradfute

1 reference

6 August 2017

6

Mike Bray

1 reference

6 August 2017

1

Natarajan Ayithan

1 reference

6 August 2017

4

Kelly S Stuthman

1 reference

6 August 2017

Keiko Ozato

7

1 reference

6 August 2017

language of work or name

English

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publication date

26 February 2015

1 reference

6 August 2017

1 reference

6 August 2017

volume

10

1 reference

6 August 2017

issue

2

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6 August 2017

page(s)

e0118345

1 reference

Creative Commons CC0 License

6 August 2017

copyright license

start time

26 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

Mechanisms of immunity in post-exposure vaccination against Ebola virus infection

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Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis

28 July 2018

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Vaccination with recombinant adenoviruses expressing Ebola virus glycoprotein elicits protection in the interferon alpha/beta receptor knock-out mouse

28 July 2018

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mAbs and Ad-vectored IFN-α therapy rescue Ebola-infected nonhuman primates when administered after the detection of viremia and symptoms

28 July 2018

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Ebola virus-like particles stimulate type I interferons and proinflammatory cytokine expression through the toll-like receptor and interferon signaling pathways.

28 July 2018

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Overcoming NS1-mediated immune antagonism involves both interferon-dependent and independent mechanisms

28 July 2018

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28 July 2018

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Interferon-β therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever

28 July 2018

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28 July 2018

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The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation

28 July 2018

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28 July 2018

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Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production

28 July 2018

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Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis

28 July 2018

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Evasion of interferon responses by Ebola and Marburg viruses

28 July 2018

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Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery

28 July 2018

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Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts

28 July 2018

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TRIM family proteins and their emerging roles in innate immunity

28 July 2018

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28 July 2018

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Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation

28 July 2018

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The IRF family transcription factors in immunity and oncogenesis

28 July 2018

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Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus

28 July 2018

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Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc

28 July 2018

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28 July 2018

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Cytokine and chemokine expression in humans infected with Sudan Ebola virus

28 July 2018

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The feedback phase of type I interferon induction in dendritic cells requires interferon regulatory factor 8.

28 July 2018

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SOCS proteins, cytokine signalling and immune regulation

28 July 2018

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Ebola virus-like particle-induced activation of NF-kappaB and Erk signaling in human dendritic cells requires the glycoprotein mucin domain.

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Effective post-exposure treatment of Ebola infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Anti-inflammatory properties of Type I interferons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Negative regulation of toll-like receptor-mediated immune responses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Negative regulation of cytokine signaling influences inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Ebola virus VP40 drives the formation of virus-like filamentous particles along with GP

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Monocyte-derived human macrophages and peripheral blood mononuclear cells infected with ebola virus secrete MIP-1alpha and TNF-alpha and inhibit poly-IC-induced IFN-alpha in vitro.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

The Ebola virus VP35 protein functions as a type I IFN antagonist.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Mouse models for filovirus infections

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Correlates of immunity to filovirus infection

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

IRF8 mutations and human dendritic-cell immunodeficiency

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Protection against filovirus infection: virus-like particle vaccines

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflammatory cytokine production and prevents endotoxemia.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

How Ebola and Marburg viruses battle the immune system

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Molecular determinants of Ebola virus virulence in mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Protection from lethal infection is determined by innate immune responses in a mouse model of Ebola virus infection

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

The role of the Type I interferon response in the resistance of mice to filovirus infection

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Evaluation of immune globulin and recombinant interferon-alpha2b for treatment of experimental Ebola virus infections

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342244

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118345

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25719445

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0118345

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference