(Q35126873)

6 August 2017

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title

Gene-targeting reveals physiological roles and complex regulation of the phosphoinositide 3-kinases (English)

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6 August 2017

Klaus Okkenhaug

2

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ORCID Public Data File 2021

author name string

Lazaros C Foukas

series ordinal

1

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6 August 2017

language of work or name

English

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publication date

1 June 2003

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Archives of Biochemistry and Biophysics

6 August 2017

published in

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6 August 2017

volume

414

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6 August 2017

issue

1

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6 August 2017

page(s)

13-18

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Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide

6 August 2017

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A function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction

7 January 2021

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DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

7 January 2021

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A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid.

7 January 2021

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7 January 2021

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PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

7 January 2021

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Autophosphorylation of p110δ phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo

7 January 2021

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Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

7 January 2021

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Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

7 January 2021

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A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

7 January 2021

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Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit

7 January 2021

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Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.

7 January 2021

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Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

7 January 2021

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The lipid phosphatase SHIP2 controls insulin sensitivity

7 January 2021

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Growth factors and insulin stimulate tyrosine phosphorylation of the 51C/SHIP2 protein

7 January 2021

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10.1016/S0003-9861(03)00177-2

7 January 2021

Identifiers

DOI

1 reference

6 August 2017

1 reference