(Q35128117)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Inhibition of RNase L and RNA-dependent protein kinase (PKR) by sunitinib impairs antiviral innate immunity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

7

Robert H Silverman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Irina Polyakova

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Patricia Kessler

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Beihua Dong

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Benjamin Dickerman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Ganes C Sen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

language of work or name

English

0 references

publication date

2 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

2 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

page(s)

26319-26326

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

2 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3143594/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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New insights into the role of RNase L in innate immunity

28 July 2018

1 reference

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RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP.

28 July 2018

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Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1

28 July 2018

1 reference

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Sunitinib-induced cardiotoxicity is mediated by off-target inhibition of AMP-activated protein kinase

28 July 2018

1 reference

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Interferon-inducible antiviral effectors

28 July 2018

1 reference

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Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

28 July 2018

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A quantitative analysis of kinase inhibitor selectivity

28 July 2018

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Viral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral response

28 July 2018

1 reference

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Small self-RNA generated by RNase L amplifies antiviral innate immunity

28 July 2018

1 reference

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Small-molecule activators of RNase L with broad-spectrum antiviral activity

28 July 2018

1 reference

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Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells

28 July 2018

1 reference

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Intracellular signaling by the unfolded protein response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

A convenient and sensitive fluorescence resonance energy transfer assay for RNase L and 2',5' oligoadenylates

28 July 2018

1 reference

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Structural basis for recognition of 2',5'-linked oligoadenylates by human ribonuclease L.

28 July 2018

1 reference

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Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase

28 July 2018

1 reference

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Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

The protein kinase complement of the human genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Antiviral actions of interferons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Basis for regulated RNA cleavage by functional analysis of RNase L and Ire1p

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Selective RNA cleavage by isolated RNase L activated with 2-5A antisense chimeric oligonucleotides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Alternative function of a protein kinase homology domain in 2', 5'-oligoadenylate dependent RNase L

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Activation of RNase L by 2',5'-oligoadenylates. Kinetic characterization.

28 July 2018

1 reference

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Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Affinity Labelling and Characterization of the ppp(A2′p)nA-Dependent Endoribonuclease from Different Mammalian Sources

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)nA) in interferon-treated cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Use of Dimethyl Suberimidate, a Cross-Linking Reagent, in Studying the Subunit Structure of Oligomeric Proteins

28 July 2018

1 reference

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The unfolded protein response signals through high-order assembly of Ire1

28 July 2018

1 reference

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Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

21 January 2018

1 reference

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2-5A-dependent RNase molecules dimerize during activation by 2-5A.

21 January 2018

1 reference

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HPC1/RNASEL mediates apoptosis of prostate cancer cells treated with 2',5'-oligoadenylates, topoisomerase I inhibitors, and tumor necrosis factor-related apoptosis-inducing ligand.

21 January 2018

1 reference

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2-5A induces a conformational change in the ankyrin-repeat domain of RNase L.

21 January 2018

1 reference

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Activation of IFN-β expression by a viral mRNA through RNase L and MDA5

21 January 2018

1 reference

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Intrinsic molecular activities of the interferon-induced 2-5A-dependent RNase

21 January 2018

1 reference

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Monoclonal antibodies to an epithelial ovarian adenocarcinoma: distinctive reactivity with xenografts of the original tumor and a cultured cell line

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143594

Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensors

27 September 2018

1 reference

12 December 2020

Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor

1 reference

12 December 2020

Antiangiogenic therapy: a universal chemosensitization strategy for cancer?

1 reference

12 December 2020

A bipartite model of 2-5A-dependent RNase L

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.253443

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21636578%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference