(Q35131789)

6 August 2017

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title

Human epithelial cell immortalization as a step in carcinogenesis (English)

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6 August 2017

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Martha R Stampfer

1

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6 August 2017

Paul Yaswen

series ordinal

2

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6 August 2017

language of work or name

English

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publication date

1 May 2003

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6 August 2017

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6 August 2017

volume

194

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6 August 2017

issue

2

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6 August 2017

page(s)

199-208

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Regulation of the human telomerase reverse transcriptase gene

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7 January 2021

Telomerase in the human organism

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Loss of p53 protein during radiation transformation of primary human mammary epithelial cells

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Cellular senescence: mitotic clock or culture shock?

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Putting the stress on senescence

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Developmental and tissue-specific regulation of mouse telomerase and telomere length

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7 January 2021

Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Insulin receptor overexpression in 184B5 human mammary epithelial cells induces a ligand-dependent transformed phenotype

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https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion

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7 January 2021

Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts

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7 January 2021

Toward a molecular understanding of human breast cancer: a hypothesis

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7 January 2021

Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism?

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7 January 2021

Oxidative stress shortens telomeres

1 reference

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7 January 2021

Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Tumor suppressors and oncogenes in cellular senescence.

1 reference

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7 January 2021

Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Structural rearrangement of the retinoblastoma gene in human breast carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Inactivation of p16 in human mammary epithelial cells by CpG island methylation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Cyclin D1 protein expression and function in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Gene amplification and overexpression of CDK4 in sporadic breast carcinomas is associated with high tumor cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Id proteins in cell cycle control and cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Immortalisation and transformation revisited

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Historical claims and current interpretations of replicative aging

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Immortalization of human mammary epithelial cells by SV40 large T-antigen involves a two step mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Telomerase activation by the E6 gene product of human papillomavirus type 16.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Telomerase activity in the human breast

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Viral oncogenes accelerate conversion to immortality of cultured conditionally immortal human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

New link in a web of human genes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

p53 mutations in human immortalized epithelial cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Chromosome analyses of human mammary epithelial cells at stages of chemical-induced transformation progression to immortality

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

The p53 gene in breast cancer: prognostic value of complementary DNA sequencing versus immunohistochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

Telomerase activity in relation to p53 status and clinico-pathological parameters in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900707-3

7 January 2021

10.1016/S0304-3835(02)00707-3

Identifiers

DOI

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6 August 2017

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