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Extracellular α-synuclein leads to microtubule destabilization via GSK-3β-dependent Tau phosphorylation in PC12 cells
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Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
title
Extracellular α-synuclein leads to microtubule destabilization via GSK-3β-dependent Tau phosphorylation in PC12 cells
(English)
1 reference
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Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
main subject
Synuclein
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author
Magdalena Gąssowska-Dobrowolska
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
3983155
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
Grzegorz A Czapski
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2
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Europe PubMed Central
PMCID
3983155
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
Beata Pająk
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3
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Europe PubMed Central
PMCID
3983155
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
Magdalena Cieślik
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4
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Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
Anna M Lenkiewicz
series ordinal
5
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Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
Agata Adamczyk
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6
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Agata Adamczyk
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Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
language of work or name
English
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publication date
10 April 2014
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Europe PubMed Central
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3983155
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retrieved
13 March 2020
published in
PLOS One
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Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
volume
9
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Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
issue
4
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Europe PubMed Central
PMCID
3983155
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
page(s)
e94259
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Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
copyright license
Creative Commons Attribution 4.0 International
start time
10 April 2014
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April 2022 Public Data File from Crossref
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cites work
Effects of cerium oxide nanoparticles on PC12 neuronal-like cells: proliferation, differentiation, and dopamine secretion
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PubMed Central
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Glycogen synthase kinase-3β activation mediates rotenone-induced cytotoxicity with the involvement of microtubule destabilization
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28 July 2018
Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.
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28 July 2018
Interaction between pathogenic proteins in neurodegenerative disorders
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28 July 2018
Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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28 July 2018
Hyperphosphorylated Tau in an α-synuclein-overexpressing transgenic model of Parkinson's disease
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28 July 2018
Tauopathic changes in the striatum of A53T α-synuclein mutant mouse model of Parkinson's disease
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28 July 2018
The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner.
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28 July 2018
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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28 July 2018
Tau protein: relevance to Parkinson's disease
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PubMed Central
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28 July 2018
Tau in Alzheimer disease and related tauopathies
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28 July 2018
Oligomeric alpha-synuclein and its role in neuronal death
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28 July 2018
Molecular interaction of α-synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells
1 reference
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PubMed Central
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28 July 2018
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers.
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28 July 2018
Alpha-Synuclein contributes to GSK-3beta-catalyzed Tau phosphorylation in Parkinson's disease models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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28 July 2018
Origins and effects of extracellular alpha-synuclein: implications in Parkinson's disease
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PubMed Central
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28 July 2018
Fine ultrastructure and biochemistry of PC12 cells: a comparative approach to understand neurotoxicity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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28 July 2018
Impairment of microtubule-dependent trafficking by overexpression of alpha-synuclein
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PubMed Central
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28 July 2018
Alpha-synuclein induces hyperphosphorylation of Tau in the MPTP model of parkinsonism
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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28 July 2018
Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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28 July 2018
Glycogen synthase kinase 3beta phosphorylates Alzheimer's disease-specific Ser396 of microtubule-associated protein tau by a sequential mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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28 July 2018
Expression of alpha-synuclein in different brain parts of adult and aged rats
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PubMed Central
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28 July 2018
alpha-Synuclein: a potent inducer of tau pathology
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28 July 2018
Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death
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PubMed Central
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28 July 2018
Tau phosphorylation in neuronal cell function and dysfunction
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PubMed Central
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28 July 2018
Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event
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PubMed Central
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28 July 2018
Part II: alpha-synuclein and its molecular pathophysiological role in neurodegenerative disease.
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PubMed Central
reference URL
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28 July 2018
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28 July 2018
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28 July 2018
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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28 July 2018
Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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27 September 2018
Alpha-synuclein promotes early neurite outgrowth in cultured primary neurons.
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PubMed Central
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27 September 2018
alpha-Synuclein enhances secretion and toxicity of amyloid beta peptides in PC12 cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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27 September 2018
Phosphorylation of tau and alpha-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer's disease, and in Parkinson's disease and related alpha-synucleinopathies.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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27 September 2018
Alpha-synuclein decreases arachidonic acid incorporation into rat striatal synaptoneurosomes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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27 September 2018
Oligomeric alpha-synuclein inhibits tubulin polymerization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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27 September 2018
Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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27 September 2018
Alpha-synuclein-positive structures in cases with sporadic Alzheimer's disease: morphology and its relationship to tau aggregation.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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27 September 2018
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983155
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27 September 2018
Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24722055
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1371/JOURNAL.PONE.0094259
1 reference
stated in
Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
ADS bibcode
2014PLoSO...994259G
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Fatcat ID
release_q3jmvg6evvcqpoqszks32mkiba
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Fatcat
reference URL
https://api.fatcat.wiki/v0/release/q3jmvg6evvcqpoqszks32mkiba
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
3983155
1 reference
stated in
Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
PubMed ID
24722055
1 reference
stated in
Europe PubMed Central
PMCID
3983155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722055%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
ResearchGate publication ID
261603491
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