(Q34600755)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

main subject

frontotemporal dementia

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Anne Gauthier-Kemper

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Carina Weissmann

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Nataliya Golovyashkina

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Zsofia Sebö-Lemke

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Volker Gerke

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Jürgen J Heinisch

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Roland Brandt

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

0 references

publication date

1 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

number of pages

15

1 reference

based on heuristic

inferred from page(s)

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

647-661

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

Tau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding.

23 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Animal models of Alzheimer's disease and frontotemporal dementia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

The GSK3 hypothesis of Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Annexins: linking Ca2+ signalling to membrane dynamics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Tau phosphorylation: physiological and pathological consequences

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Cdk5 deregulation in the pathogenesis of Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Analysis of binding reactions by fluorescence recovery after photobleaching

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Annexins--unique membrane binding proteins with diverse functions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Mutant (R406W) human tau is hyperphosphorylated and does not efficiently bind microtubules in a neuronal cortical cell model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Tau assembly in inducible transfectants expressing wild-type or FTDP-17 tau.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

A photoactivatable GFP for selective photolabeling of proteins and cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Annexins: from structure to function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Frontotemporal dementia and tauopathy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Comparative genetic and physiological studies of the MAP kinase Mpk1p from Kluyveromyces lactis and Saccharomyces cerevisiae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Missense tau mutations identified in FTDP-17 have a small effect on tau-microtubule interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Stable expression in Chinese hamster ovary cells of mutated tau genes causing frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Annexin gene structures and molecular evolutionary genetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Annexins and membrane dynamics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Frontotemporal dementia and parkinsonism linked to chromosome 17: a consensus conference. Conference Participants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Alterations of annexin expression in pathological neuronal and glial reactions. Immunohistochemical localization of annexins I, II (p36 and p11 subunits), IV, and VI in the human hippocampus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Regulation of microtubule protein levels during cellular morphogenesis in nerve growth factor-treated PC12 cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Microtubules containing acetylated alpha-tubulin in mammalian cells in culture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Expression of annexins as a function of cellular growth state

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Increases in p11 and annexin II proteins correlate with differentiation in the PC12 pheochromocytoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

The tight association of the tyrosine kinase substrate annexin II with the submembranous cytoskeleton depends on intact p11- and Ca(2+)-binding sites

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044115

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

7 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

FTDP-17 mutations compromise the ability of tau to regulate microtubule dynamics in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Effects of FTDP-17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3beta identified by mass spectrometry demonstrate certain mutations exert long-range conformational changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Mutational analysis in early-onset familial dementia in the Japanese population. The role of PSEN1 and MAPT R406W mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Neuritogenesis and the nerve growth factor-induced differentiation of PC-12 cells requires annexin II-mediated plasmin generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Global hairpin folding of tau in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Inverse and distinct modulation of tau-dependent neurodegeneration by presenilin 1 and amyloid-beta in cultured cortical neurons: evidence that tau phosphorylation is the limiting factor in amyloid-beta-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Alzheimer disease-like clinical phenotype in a family with FTDP-17 caused by a MAPT R406W mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Molecular analysis of mutant and wild-type tau deposited in the brain affected by the FTDP-17 R406W mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

The tau R406W mutation causes progressive presenile dementia with bitemporal atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Divergent pathways mediate spine alterations and cell death induced by amyloid-beta, wild-type tau, and R406W tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Microtubule binding and trapping at the tip of neurites regulate tau motion in living neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201007161

Fibrillogenic nuclei composed of P301L mutant tau induce elongation of P301L tau but not wild-type tau

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21339331

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21339331

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201007161

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21339331%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference