(Q35148751)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Lessons from hepatocyte-specific Cyp51 knockout mice: impaired cholesterol synthesis leads to oval cell-driven liver injury (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

0 references

Francisco M Gutierrez-Mariscal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Monika Lewinska

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Ingemar Björkhem

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

7

Rolf Gebhardt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Gregor Lorbek

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Martina Perše

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Jera Jeruc

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Peter Juvan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Rok Keber

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Simon Horvat

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Damjana Rozman

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

5 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

8777

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

2 March 2020

copyright license

start time

5 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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13 July 2018

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13 July 2018

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Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)

13 July 2018

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13 July 2018

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Cholesterol biosynthesis and homeostasis in regulation of the cell cycle

13 July 2018

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Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

13 July 2018

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Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis

13 July 2018

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Tetradian oscillation of estrogen receptor α is necessary to prevent liver lipid deposition.

13 July 2018

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Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease

13 July 2018

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Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood

13 July 2018

1 reference

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C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia

13 July 2018

1 reference

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Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases

13 July 2018

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Spontaneous repopulation of β-catenin null livers with β-catenin-positive hepatocytes after chronic murine liver injury

13 July 2018

1 reference

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Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome

13 July 2018

1 reference

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Liver X Receptor: an oxysterol sensor and a major player in the control of lipogenesis.

13 July 2018

1 reference

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Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments.

13 July 2018

1 reference

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Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis

13 July 2018

1 reference

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The senescence-associated secretory phenotype: the dark side of tumor suppression

13 July 2018

1 reference

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Pathogenesis of non-alcoholic fatty liver disease.

13 July 2018

1 reference

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Signaling networks in hepatic oval cell activation.

13 July 2018

1 reference

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Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha.

13 July 2018

1 reference

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Cellular cholesterol trafficking and compartmentalization

13 July 2018

1 reference

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Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Dual roles for cholesterol in mammalian cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Cholesterogenic lanosterol 14alpha-demethylase (CYP51) is an immediate early response gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol

13 July 2018

1 reference

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Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.

13 July 2018

1 reference

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Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Generation of viable cholesterol-free mice

13 July 2018

1 reference

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13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Sex differences in the hepatic cholesterol sensing mechanisms in mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Liver-specific deletion of 3-hydroxy-3-methylglutaryl coenzyme A reductase causes hepatic steatosis and death.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Vacuolation in hepatocyte nuclei is a marker of senescence.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

A lipidomic analysis of nonalcoholic fatty liver disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Baseline and stress-induced plasma corticosterone concentrations of mice selectively bred for high voluntary wheel running

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Adiponectin plays an important role in efficient energy usage under energy shortage.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Liver inflammation and cytokine production, but not acute phase protein synthesis, accompany the adult liver progenitor (oval) cell response to chronic liver injury

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Characterization of liver involvement in defects of cholesterol biosynthesis: long-term follow-up and review.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350092

Sex- or gender-specific medicine in hepatology

27 September 2018

1 reference

12 December 2020

Cholesterol synthesis is increased and absorption decreased in non-alcoholic fatty liver disease independent of obesity

1 reference

12 December 2020

Beyond lipids, pharmacological PPARalpha activation has important effects on amino acid metabolism as studied in the rat

1 reference

12 December 2020

The not-so-simple HDL story: Is it time to revise the HDL cholesterol hypothesis?

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP08777

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

25739789

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739789%20AND%20SRC:MED&resulttype=core&format=json