(Q35150831)

English

Patients with tuberculosis disease have Mycobacterium tuberculosis-specific CD8 T cells with a pro-apoptotic phenotype and impaired proliferative capacity, which is not restored following treatment

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Patients with tuberculosis disease have Mycobacterium tuberculosis-specific CD8 T cells with a pro-apoptotic phenotype and impaired proliferative capacity, which is not restored following treatment (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Mycobacterium tuberculosis

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apoptotic process

1 reference

based on heuristic

inferred from title

Willem Albert Hanekom

7

object named as

Willem A Hanekom

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

6

object named as

Marwou de Kock

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Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Cheryl L Day

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Noella D Moshi

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Deborah A Abrahams

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Michele van Rooyen

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Terrence O'rie

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

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publication date

16 April 2014

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Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

e94949

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

copyright license

Creative Commons Attribution 4.0 International

16 April 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

1 reference

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Human Mycobacterium tuberculosis CD8 T Cell Antigens/Epitopes Identified by a Proteomic Peptide Library

1 reference

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Shedding light on apoptosis at subcellular membranes

1 reference

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1 reference

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Acute cytomegalovirus infection is associated with increased frequencies of activated and apoptosis-vulnerable T cells in HIV-1-infected infants

1 reference

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Pathogen-induced proapoptotic phenotype and high CD95 (Fas) expression accompany a suboptimal CD8+ T-cell response: reversal by adenoviral vaccine.

1 reference

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The influence of HIV on CD127 expression and its potential implications for IL-7 therapy

1 reference

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CD8(+) T cells: foot soldiers of the immune system

1 reference

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13 July 2018

Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load

1 reference

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13 July 2018

T cell exhaustion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

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1 reference

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13 July 2018

Genome-based in silico identification of new Mycobacterium tuberculosis antigens activating polyfunctional CD8+ T cells in human tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Higher human CD4 T cell response to novel Mycobacterium tuberculosis latency associated antigens Rv2660 and Rv2659 in latent infection compared with tuberculosis disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Generation of effector CD8+ T cells and their conversion to memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Understanding latent tuberculosis: a moving target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

T-cell exhaustion: characteristics, causes and conversion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

High rates of recurrence in HIV-infected and HIV-uninfected patients with tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Retracted: Analysis of Mycobacterium tuberculosis-Specific CD8 T-Cells in Patients with Active Tuberculosis and in Individuals with Latent Infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

A critical role for CD8 T cells in a nonhuman primate model of tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Impaired expression of perforin and granulysin in CD8+ T cells at the site of infection in human chronic pulmonary tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

CD8 T cell dysfunction during chronic viral infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Interleukin-7 receptor expression: intelligent design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Functional signatures of protective antiviral T-cell immunity in human virus infections.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Mycobacterium tuberculosis growth control by lung macrophages and CD8 cells from patient contacts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Expression of killer cell lectin-like receptor G1 on antigen-specific human CD8+ T lymphocytes during active, latent, and resolved infection and its relation with CD57

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

CD8+ T cell-mediated suppression of intracellular Mycobacterium tuberculosis growth in activated human macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

HLA-B*35-restricted CD8 T cell epitopes in the antigen 85 complex of Mycobacterium tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

The relative importance of T cell subsets in immunity and immunopathology of airborne Mycobacterium tuberculosis infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Human CD8(+) T cells specific for Mycobacterium tuberculosis secreted antigens in tuberculosis patients and healthy BCG-vaccinated controls in The Gambia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Antimicrobial activity of MHC class I-restricted CD8+ T cells in human tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Depletion of CD4(+) T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon gamma and nitric oxide synthase 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Ineffective cellular immune response associated with T-cell apoptosis in susceptible Mycobacterium bovis BCG-infected mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Relative contributions of distinct MHC class I-dependent cell populations in protection to tuberculosis infection in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

An antimicrobial activity of cytolytic T cells mediated by granulysin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Identification of nitric oxide synthase as a protective locus against tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Apoptosis associated with ex vivo down-regulation of Bcl-2 and up-regulation of Fas in potential cytotoxic CD8+ T lymphocytes during HIV infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

T-cell-mediated protection of mice against virulent Mycobacterium tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Effects of in vivo T lymphocyte subset depletion on mycobacterial infections in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

13 July 2018

Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

27 September 2018

Phenotypical and functional analysis of memory and effector human CD8 T cells specific for mycobacterial antigens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

27 September 2018

Characterization of a Mycobacterium tuberculosis peptide that is recognized by human CD4+ and CD8+ T cells in the context of multiple HLA alleles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

27 September 2018

Virus-specific CD8 T cells in peripheral tissues are more resistant to apoptosis than those in lymphoid organs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

27 September 2018

Differential sensitivity of naive and memory CD8+ T cells to apoptosis in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

27 September 2018

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989259

27 September 2018

Dominant TNF-α+ Mycobacterium tuberculosis–specific CD4+ T cell responses discriminate between latent infection and active disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0094949

21 January 2018

Mechanisms of Apoptosis of T-Cells in Human Tuberculosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0094949

21 January 2018

Apoptosis and T Cell Hyporesponsiveness in Pulmonary Tuberculosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0094949

21 January 2018

High frequencies of circulating IFN-γ-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restrictedMycobacterium tuberculosis epitope inM. tuberculosis-infected subjects without disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24740417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classically restricted human CD8+ T lymphocytes derived from Mycobacterium tuberculosis-infected cells: definition of antigenic specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24740417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordinate expression of CC chemokine ligand 5, granulysin, and perforin in CD8+ T cells provides a host defense mechanism against Mycobacterium tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24740417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24740417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inverse expression of bcl-2 protein and Fas antigen in lymphoblasts in peripheral lymph nodes and activated peripheral blood T and B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24740417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24740417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mycobacterium tuberculosis-specific CD8+T cells are functionally and phenotypically different between latent infection and active disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24740417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0094949

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

2014PLoSO...994949D

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

0 references

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