(Q35166600)

6 August 2017

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title

Biosynthesis of endocannabinoids and their modes of action in neurodegenerative diseases (English)

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6 August 2017

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Harald S Hansen

8

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Klaas Nicolay

object named as

Klaas Nicolay

5

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author name string

Mario van der Stelt

1

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6 August 2017

Henrik H Hansen

2

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6 August 2017

Wouter B Veldhuis

3

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6 August 2017

Peter R Bär

4

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6 August 2017

Gerrit A Veldink

6

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6 August 2017

Johannes F G Vliegenthart

7

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6 August 2017

publication date

1 January 2003

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6 August 2017

published in

Neurotoxicity Research

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6 August 2017

volume

5

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6 August 2017

issue

3

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6 August 2017

page(s)

183-200

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https://scigraph.springernature.com/pub.10.1007/bf03033139

6 August 2017

exact match

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cites work

Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1007%2FBF03033139

Safety, tolerability, and efficacy of orally administered cannabinoids in MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033139

N-acylethanolamine phospholipid metabolism in normal and ischemic rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033139

Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033139

CB1 cannabinoid receptor induction in experimental stroke

21 January 2018

1 reference

12 December 2020

Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration

1 reference

12 December 2020

Acute neuronal injury, excitotoxicity, and the endocannabinoid system

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12 December 2020

Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission

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12 December 2020

Cannabinoids control spasticity and tremor in a multiple sclerosis model

1 reference

12 December 2020

Effects of delta-9-tetrahydrocannabinol on sensory evoked hippocampal activity in the rat: principal components analysis and sequential dependency.

1 reference

12 December 2020

Stress-induced generation of N-acylethanolamines in mouse epidermal JB6 P+ cells

1 reference

12 December 2020

Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity

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12 December 2020

Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity.

1 reference

12 December 2020

Identification of molecular species of glycerophospholipids and sphingomyelin using electrospray mass spectrometry

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12 December 2020

An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

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12 December 2020

Effects of systemic 3-nitropropionic acid-induced lesions of the dorsal striatum on cannabinoid and mu-opioid receptor binding in the basal ganglia.

1 reference

12 December 2020

Characterization of glutamate-induced formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons.

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12 December 2020

Postsynaptic endocannabinoid release is critical to long-term depression in the striatum

1 reference

12 December 2020

Neurotoxicity of glutamate in chick telencephalon neurons: reduction of toxicity by preincubation with carbachol, but not by the endogenous fatty acid amides anandamide and palmitoylethanolamide

1 reference

12 December 2020

Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates.

1 reference

12 December 2020

Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor

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12 December 2020

Neurodegenerative disorders and ischemic brain diseases.

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12 December 2020

The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism

1 reference

12 December 2020

Brain monoglyceride lipase participating in endocannabinoid inactivation

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12 December 2020

Control of the cell survival/death decision by cannabinoids

1 reference

12 December 2020

Adjuncts to dopamine replacement: a pragmatic approach to reducing the problem of dyskinesia in Parkinson's disease

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12 December 2020

Pharmacology of cannabinoid CB1 and CB2 receptors.

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12 December 2020

The effect of delta-9-tetrahydrocannabinol on forebrain ischemia in rat

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12 December 2020

The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons

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12 December 2020

The anandamide transport inhibitor AM404 activates vanilloid receptors.

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12 December 2020

The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine.

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12 December 2020

Accumulation of the anandamide precursor and other N-acylethanolamine phospholipids in infant rat models of in vivo necrotic and apoptotic neuronal death

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12 December 2020

Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP.

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12 December 2020

Multiple sclerosis: more than inflammation and demyelination

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12 December 2020

Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine.

1 reference

12 December 2020

Striatal cannabinoid CB1 receptor mRNA expression is decreased in the reserpine-treated rat model of Parkinson's disease.

1 reference

12 December 2020

D(2), but not D(1) dopamine receptor agonists potentiate cannabinoid-induced sedation in nonhuman primates.

1 reference

12 December 2020

Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission.

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12 December 2020

Modulation of transmitter release via presynaptic cannabinoid receptors

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12 December 2020

Blockade of cannabinoid CB(1) receptor function protects against in vivo disseminating brain damage following NMDA-induced excitotoxicity.

1 reference

12 December 2020

The cannabinoid receptor agonist WIN 55,212-2 reduces D2, but not D1, dopamine receptor-mediated alleviation of akinesia in the reserpine-treated rat model of Parkinson's disease

1 reference

12 December 2020

Dopamine activation of endogenous cannabinoid signaling in dorsal striatum

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12 December 2020

Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants

1 reference

12 December 2020

Cannabinoid CB1 receptors are localized primarily on cholecystokinin-containing GABAergic interneurons in the rat hippocampal formation

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12 December 2020

Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system

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12 December 2020

2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-alpha production in murine macrophages, and in mice

1 reference

12 December 2020

Relation between free fatty acid and acyl-CoA concentrations in rat brain following decapitation.

1 reference

12 December 2020

Pathobiology of ischaemic stroke: an integrated view

1 reference

12 December 2020

Phosphatidic acid as the biosynthetic precursor of the endocannabinoid 2-arachidonoylglycerol in intact mouse neuroblastoma cells stimulated with ionomycin.

1 reference

12 December 2020

Changes in cannabinoid CB(1) receptors in striatal and cortical regions of rats with experimental allergic encephalomyelitis, an animal model of multiple sclerosis

1 reference

12 December 2020

Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease

1 reference

12 December 2020

Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens

1 reference

12 December 2020

2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor

1 reference

12 December 2020

Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat.

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12 December 2020

Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors

1 reference

12 December 2020

Loss of cannabinoid CB(1) receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington's disease

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12 December 2020

Loss of mRNA levels, binding and activation of GTP-binding proteins for cannabinoid CB1 receptors in the basal ganglia of a transgenic model of Huntington's disease

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12 December 2020

Cannabinoid receptor activation and elevated cyclic AMP reduce glutamate neurotoxicity.

1 reference

12 December 2020

Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function.

1 reference

12 December 2020

Endocannabinoids control spasticity in a multiple sclerosis model

1 reference

12 December 2020

Accumulation of N-acyl-ethanolamine phospholipids in rat brains during post-decapitative ischemia: a 31p NMR study.

1 reference

12 December 2020

Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells.

1 reference

12 December 2020

Neuroprotection by Delta9-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity.

1 reference

12 December 2020

Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation

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12 December 2020

Role of the endogenous cannabinoid system as a modulator of dopamine transmission: implications for Parkinson's disease and schizophrenia

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12 December 2020

Receptor-dependent formation of endogenous cannabinoids in cortical neurons

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12 December 2020

N-Acylethanolamines and precursor phospholipids - relation to cell injury

1 reference

12 December 2020

Glutamate excitotoxicity in a model of multiple sclerosis

1 reference

12 December 2020

The role of cannabinoids in neurodegenerative diseases

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12 December 2020

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1 reference

12 December 2020

Cannabinoids enhance NMDA-elicited Ca2+ signals in cerebellar granule neurons in culture.

1 reference

12 December 2020

Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain

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12 December 2020

Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors

1 reference

12 December 2020

Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity

1 reference

12 December 2020

A new concept in neurodegeneration: TNFalpha is a silencer of survival signals

1 reference

12 December 2020

Simultaneous intracellular calcium and sodium flux imaging in human vanilloid receptor 1 (VR1)-transfected human embryonic kidney cells: a method to resolve ionic dependence of VR1-mediated cell death

1 reference

12 December 2020

Pain modulation by release of the endogenous cannabinoid anandamide

1 reference

12 December 2020

Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model

1 reference

12 December 2020

Functional changes of the basal ganglia circuitry in Parkinson's disease.

1 reference

12 December 2020

Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes

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12 December 2020

Functional expression of cell surface cannabinoid CB1 receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons

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12 December 2020

Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain.

1 reference

12 December 2020

Glycerophospholipids in brain: their metabolism, incorporation into membranes, functions, and involvement in neurological disorders

1 reference

12 December 2020

Chronic L-DOPA treatment increases striatal cannabinoid CB1 receptor mRNA expression in 6-hydroxydopamine-lesioned rats

1 reference

12 December 2020

Functions of cannabinoid receptors in the hippocampus

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12 December 2020

Endogenous cannabinoid as a retrograde messenger from depolarized postsynaptic neurons to presynaptic terminals

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12 December 2020

A novel pathway for lipid biosynthesis: the direct acylation of glycerol

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12 December 2020

Cannabinoids and neuroprotection

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12 December 2020

Membrane localization of N-acylphosphatidylethanolamine in central neurons: studies with exogenous phospholipases.

1 reference

12 December 2020

Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus.

1 reference

12 December 2020

Substantial species differences in relation to formation and degradation of N-acyl-ethanolamine phospholipids in heart tissue: an enzyme activity study

1 reference

12 December 2020

The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase

1 reference

12 December 2020

Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease.

1 reference

12 December 2020

Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide

1 reference

12 December 2020

Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures.

1 reference

12 December 2020

Biosynthesis of N-acylethanolamine phospholipids by dog brain preparations.

1 reference

12 December 2020

Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human

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12 December 2020

Metabotropic glutamate receptors drive the endocannabinoid system in hippocampus.

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12 December 2020

Short-term retrograde inhibition of GABAergic synaptic currents in rat Purkinje cells is mediated by endogenous cannabinoids.

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12 December 2020

The role of excitotoxicity in neurodegenerative disease: implications for therapy

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12 December 2020

A second endogenous cannabinoid that modulates long-term potentiation

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12 December 2020

Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington's disease mice

1 reference

12 December 2020

Cellular transport of anandamide, 2-arachidonoylglycerol and palmitoylethanolamide--targets for drug development?

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12 December 2020

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

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12 December 2020

The palmitoylethanolamide and oleamide enigmas : are these two fatty acid amides cannabimimetic?

1 reference

12 December 2020

Cannabinoid effects in basal ganglia in a rat model of Parkinson's disease.

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12 December 2020

A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain

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12 December 2020

Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats

1 reference

12 December 2020

The cannabinoid agonist Win55,212-2 inhibits calcium channels by receptor-mediated and direct pathways in cultured rat hippocampal neurons.

1 reference

12 December 2020

Changes in endocannabinoid transmission in the basal ganglia in a rat model of Huntington's disease

1 reference

12 December 2020

Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1.

1 reference

12 December 2020

Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel

1 reference

12 December 2020

Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol.

1 reference

12 December 2020

Suppression of experimental autoimmune encephalomyelitis by cannabinoids

1 reference

12 December 2020

Age dependent accumulation of N-acyl-ethanolamine phospholipids in ischemic rat brain. A (31)P NMR and enzyme activity study

1 reference

12 December 2020

Characterization of the diarylether sulfonylester (-)-(R)-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a potent cannabinoid receptor agonist with neuroprotective properties

1 reference

12 December 2020

Exogenous anandamide protects rat brain against acute neuronal injury in vivo.

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12 December 2020

Neuronal cell death: a demise with different shapes.

1 reference

12 December 2020

Increased cannabinoid CB1 receptor binding and activation of GTP-binding proteins in the basal ganglia of patients with Parkinson's syndrome and of MPTP-treated marmosets

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12 December 2020

Delta 9-tetrahydrocannabinol induces the apoptotic pathway in cultured cortical neurones via activation of the CB1 receptor.

1 reference

12 December 2020

Delta 9-tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis

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12 December 2020

N-acylphosphatidylethanolamine-hydrolysing phospholipase D lacks the ability to transphosphatidylate

1 reference

12 December 2020

Modulation of GABAergic transmission in the globus pallidus by the synthetic cannabinoid WIN 55,212-2.

1 reference

12 December 2020

The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease

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12 December 2020

Endocannabinoids and basal ganglia functionality.

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12 December 2020

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

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12 December 2020

Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide

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12 December 2020

A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus

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12 December 2020

Metabolism of N-acylethanolamine phospholipids by a mammalian phosphodiesterase of the phospholipase D type

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12 December 2020

Dopaminergic regulation of cannabinoid receptor mRNA levels in the rat caudate-putamen: an in situ hybridization study

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12 December 2020

Effects of cannabinoid receptor stimulation and blockade on catalepsy produced by dopamine receptor antagonists

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12 December 2020

Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action.

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12 December 2020

Control of pain initiation by endogenous cannabinoids.

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12 December 2020

Recent advances in Huntington's disease: implications for experimental therapeutics

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12 December 2020

Cannabinoids and brain injury: therapeutic implications

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12 December 2020

2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist: identification as one of the major species of monoacylglycerols in various rat tissues, and evidence for its generation through CA2+-dependent and -independent mechanisms

1 reference

12 December 2020

Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells

1 reference

12 December 2020

Evidence for a new G protein-coupled cannabinoid receptor in mouse brain.

1 reference

12 December 2020

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

1 reference

12 December 2020

Activation of the cannabinoid receptor by delta 9-tetrahydrocannabinol reduces gamma-aminobutyric acid uptake in the globus pallidus.

1 reference

12 December 2020

Unilateral 6-hydroxydopamine lesions of nigrostriatal dopaminergic neurons increased CB1 receptor mRNA levels in the caudate-putamen

1 reference

12 December 2020

The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1.

1 reference

12 December 2020

Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance

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12 December 2020

The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice

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12 December 2020

Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells

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12 December 2020

Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor

1 reference

12 December 2020

CP 55,940 protects against ischemia-induced electroencephalographic flattening and hyperlocomotion in Mongolian gerbils

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12 December 2020

Identifiers

DOI

10.1007/BF03033139

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6 August 2017

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