(Q35167110)

6 August 2017

1 reference

title

Applications of NMR to structure-based drug design in structural genomics (English)

1 reference

6 August 2017

1 reference

Robert Powers

1

1 reference

6 August 2017

publication date

1 January 2002

1 reference

Journal of Structural and Functional Genomics

6 August 2017

published in

1 reference

6 August 2017

volume

2

1 reference

6 August 2017

issue

2

1 reference

6 August 2017

page(s)

113-123

1 reference

https://scigraph.springernature.com/pub.10.1023/a:1020445506369

6 August 2017

exact match

0 references

cites work

NMR techniques for characterization of ligand binding: utility for lead generation and optimization in drug discovery

1 reference

12 December 2020

The application of size exclusion chromatography and computer simulation to study the thermodynamic and kinetic parameters for short-lived dissociable protein aggregates

1 reference

12 December 2020

Large-scale protein structure modeling of the Saccharomyces cerevisiae genome

1 reference

12 December 2020

Determination of three-dimensional structures of proteins and nucleic acids in solution by nuclear magnetic resonance spectroscopy

1 reference

12 December 2020

An overview of structural genomics.

1 reference

12 December 2020

Study of conformational rearrangement and refinement of structural homology models by the use of heteronuclear dipolar couplings

1 reference

12 December 2020

Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy

1 reference

12 December 2020

Automated assignment of ambiguous nuclear overhauser effects with ARIA

1 reference

12 December 2020

Automated analysis of NMR assignments and structures for proteins.

1 reference

12 December 2020

MS/NMR: a structure-based approach for discovering protein ligands and for drug design by coupling size exclusion chromatography, mass spectrometry, and nuclear magnetic resonance spectroscopy

1 reference

12 December 2020

Structure-based design of a new class of anti-inflammatory drugs: secretory phospholipase A(2) inhibitors, SPI.

1 reference

12 December 2020

The structure of inosine 5'-monophosphate dehydrogenase and the design of novel inhibitors

1 reference

12 December 2020

Protein structural motif recognition via NMR residual dipolar couplings.

1 reference

12 December 2020

Determining affinity-selected ligands and estimating binding affinities by online size exclusion chromatography/liquid chromatography-mass spectrometry

1 reference

12 December 2020

Macromolecular crystallography as a tool for investigating drug, enzyme and receptor interactions.

1 reference

12 December 2020

Solution structure of human IL-13 and implication for receptor binding

1 reference

12 December 2020

Two-, three-, and four-dimensional NMR methods for obtaining larger and more precise three-dimensional structures of proteins in solution.

1 reference

12 December 2020

Automatic assignment of NOESY cross peaks and determination of the protein structure of a new world scorpion neurotoxin using NOAH/DIAMOD

1 reference

12 December 2020

Intracellular detection assays for high-throughput screening

1 reference

12 December 2020

New assay technologies for high-throughput screening

1 reference

12 December 2020

The use of 3D structural data in the design of specific factor Xa inhibitors

1 reference

12 December 2020

De novo determination of protein backbone structure from residual dipolar couplings using Rosetta

1 reference

12 December 2020

Impact of transverse relaxation optimized spectroscopy (TROSY) on NMR as a technique in structural biology

1 reference

12 December 2020

Rapid methods for screening low molecular mass compounds non-covalently bound to proteins using size exclusion and mass spectrometry applied to inhibitors of human cytomegalovirus protease

1 reference

12 December 2020

Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design

1 reference

12 December 2020

Chemical shifts as a tool for structure determination

1 reference

12 December 2020

Automation of X-ray crystallography

1 reference

12 December 2020

High-resolution solution structure of the catalytic fragment of human collagenase-3 (MMP-13) complexed with a hydroxamic acid inhibitor

1 reference

12 December 2020

Approaches and strategies for the treatment of influenza virus infections

1 reference

12 December 2020

The art and practice of structure-based drug design: A molecular modeling perspective

1 reference

12 December 2020

Homology model for oncostatin M based on NMR structural data.

1 reference

12 December 2020

Early discovery drug screening using mass spectrometry

1 reference

12 December 2020

The SHAPES strategy: an NMR-based approach for lead generation in drug discovery.

1 reference

12 December 2020

Protein NMR spectroscopy in structural genomics

1 reference

12 December 2020

From genes to protein structure and function: novel applications of computational approaches in the genomic era.

1 reference

12 December 2020

Automated 2D NOESY assignment and structure calculation of Crambin(S22/I25) with the self-correcting distance geometry based NOAH/DIAMOD programs

1 reference

12 December 2020

Signalling the fat controller

1 reference

12 December 2020

Applications of NMR in drug discovery

1 reference

12 December 2020

The application of high-throughput screening to novel lead discovery

1 reference

12 December 2020

Discovering high-affinity ligands for proteins: SAR by NMR

1 reference

12 December 2020

Global Folds of Highly Deuterated, Methyl-Protonated Proteins by Multidimensional NMR†

1 reference

12 December 2020

Rapid determination of protein folds using residual dipolar couplings

1 reference

12 December 2020

Solution NMR structure and folding dynamics of the N terminus of a rat non-muscle alpha-tropomyosin in an engineered chimeric protein

1 reference

12 December 2020

Current state of automated crystallographic data analysis.

1 reference

12 December 2020

Determination of protein backbone structure using only residual dipolar couplings.

1 reference

12 December 2020

Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis

1 reference

12 December 2020

NMR solution structure of the catalytic fragment of human fibroblast collagenase complexed with a sulfonamide derivative of a hydroxamic acid compound

1 reference

12 December 2020

De novo protein structure determination using sparse NMR data.

1 reference

12 December 2020

DipoCoup: A versatile program for 3D-structure homology comparison based on residual dipolar couplings and pseudocontact shifts.

1 reference

12 December 2020

Technological advances in high-throughput screening

1 reference

12 December 2020

Protein structure modeling for structural genomics.

1 reference

12 December 2020

Evaluation of the utility of NMR structures determined from minimal NOE-based restraints for structure-based drug design, using MMP-1 as an example.

1 reference

12 December 2020

Direct measurement of distances and angles in biomolecules by NMR in a dilute liquid crystalline medium

1 reference

12 December 2020

High resolution NMR for screening ligand/protein binding.

1 reference

12 December 2020

Structure-based design of enzyme inhibitors and receptor ligands.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1020445506369

1 reference

Dimensions Publication ID

6 August 2017

1029590661

0 references

1 reference