(Q35170050)

6 August 2017

title

Neonatal Fc receptor blockade by Fc engineering ameliorates arthritis in a murine model (English)

1 reference

6 August 2017

1 reference

5

Raimund J Ober

1 reference

6 August 2017

6

E Sally Ward

1 reference

6 August 2017

Dipesh A Patel

1

1 reference

6 August 2017

Alberto Puig-Canto

series ordinal

2

1 reference

6 August 2017

Dilip Kumar Challa

series ordinal

3

1 reference

6 August 2017

Héctor Perez Montoyo

series ordinal

4

1 reference

6 August 2017

language of work or name

English

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publication date

20 June 2011

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6 August 2017

published in

Journal of Immunology

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6 August 2017

volume

187

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6 August 2017

issue

2

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6 August 2017

page(s)

1015-1022

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B cells as therapeutic targets in SLE.

6 August 2017

cites work

1 reference

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Rituximab specifically depletes short-lived autoreactive plasma cells in a mouse model of inflammatory arthritis

13 July 2018

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CD19: a promising B cell target for rheumatoid arthritis

13 July 2018

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Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.

13 July 2018

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Analyses of the recycling receptor, FcRn, in live cells reveal novel pathways for lysosomal delivery.

13 July 2018

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Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

13 July 2018

1 reference

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High accuracy 3D quantum dot tracking with multifocal plane microscopy for the study of fast intracellular dynamics in live cells

13 July 2018

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Steroids and immunosuppressant drugs in myasthenia gravis

13 July 2018

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Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.

13 July 2018

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Novel therapies of lupus nephritis

13 July 2018

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Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn

13 July 2018

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Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies

13 July 2018

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Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor

13 July 2018

1 reference

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Basic principles of intravenous immunoglobulin (IVIg) treatment

13 July 2018

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Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases

13 July 2018

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The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease

13 July 2018

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The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan

13 July 2018

1 reference

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Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.

13 July 2018

1 reference

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Effects of intravenous immunoglobulin on platelet count and antiplatelet antibody disposition in a rat model of immune thrombocytopenia.

13 July 2018

1 reference

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Arthritogenic monoclonal antibodies from K/BxN mice

13 July 2018

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Immunomodulation of autoimmune and inflammatory diseases with intravenous immune globulin

13 July 2018

1 reference

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Genetic influences on the end-stage effector phase of arthritis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Sedimentation equilibrium analysis of recombinant mouse FcRn with murine IgG1.

13 July 2018

1 reference

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Characterization of the 2:1 complex between the class I MHC-related Fc receptor and its Fc ligand in solution

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

In vivo administration of intravenous immunoglobulin (IVIg) can lead to enhanced erythrocyte sequestration.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Stoichiometry of the interaction between the major histocompatibility complex-related Fc receptor and its Fc ligand

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

The elderberry (Sambucus nigra L.) bark lectin recognizes the Neu5Ac(alpha 2-6)Gal/GalNAc sequence.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Mechanisms of action of intravenous immunoglobulin therapy and potential use in autoimmune connective tissue diseases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Antibodies in the breakdown lane.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Dynamic visualization of a joint-specific autoimmune response through positron emission tomography

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Arthritis critically dependent on innate immune system players

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157913

Antibody framework residues affecting the conformation of the hypervariable loops

27 September 2018

1 reference

12 December 2020

Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice

1 reference

12 December 2020

Organ-specific disease provoked by systemic autoimmunity

1 reference

12 December 2020

Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesis

1 reference

12 December 2020

Pharmacokinetic effects of 4C9, an anti-FcRn antibody, in rats: implications for the use of FcRn inhibitors for the treatment of humoral autoimmune and alloimmune conditions

1 reference

12 December 2020

Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

1 reference

12 December 2020

Shortage of human intravenous immunoglobulin—reasons and possible solutions

1 reference

12 December 2020

Amelioration of experimental autoimmune myasthenia gravis in rats by neonatal FcR blockade

1 reference

12 December 2020

Catabolism of the murine IgG1 molecule: evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice

1 reference

12 December 2020

Accelerated autoantibody clearance by intravenous immunoglobulin therapy: studies in experimental models to determine the magnitude and time course of the effect

1 reference

12 December 2020

The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs

1 reference

12 December 2020

Three-dimensional structure of an antigen-antibody complex at 2.8 A resolution

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1003780

1 reference

6 August 2017

1 reference

6 August 2017

1 reference