(Q35170203)

6 August 2017

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title

Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury (English)

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6 August 2017

J Gordon Boyd

1

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6 August 2017

Tessa Gordon

series ordinal

2

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6 August 2017

publication date

1 June 2003

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6 August 2017

published in

Molecular Neurobiology

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6 August 2017

volume

27

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6 August 2017

issue

3

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6 August 2017

page(s)

277-324

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https://scigraph.springernature.com/pub.10.1385/mn:27:3:277

6 August 2017

exact match

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cites work

Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain.

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12 December 2020

Effects of neurotrophic factors on motoneuron survival following axonal injury in newborn rats

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12 December 2020

Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS.

1 reference

12 December 2020

Activation of a novel human transforming gene, ret, by DNA rearrangement

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12 December 2020

Changes in cytoskeletal protein synthesis following axon injury and during axon regeneration

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12 December 2020

Signal transduction through lipid second messengers

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12 December 2020

Nerve injury and regeneration: basic insights and therapeutic interventions

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12 December 2020

c-Jun is a downstream target for ceramide-activated protein phosphatase in A431 cells.

1 reference

12 December 2020

Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons.

1 reference

12 December 2020

Spatiotemporal increases in epidermal growth factor receptors following peripheral nerve injury

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12 December 2020

Peripheral but not central axotomy induces changes in Janus kinases (JAK) and signal transducers and activators of transcription (STAT).

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12 December 2020

Reciprocal modulation of TrkA and p75NTR affinity states is mediated by direct receptor interactions

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12 December 2020

Axotomy induces a different modulation of both low-affinity nerve growth factor receptor and choline acetyltransferase between adult rat spinal and brainstem motoneurons

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12 December 2020

Coupling of the p75 neurotrophin receptor to sphingolipid signaling.

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12 December 2020

p75 and Trk: a two-receptor system

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12 December 2020

From visual experience to visual function: roles of neurotrophins

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12 December 2020

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

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12 December 2020

Discordant expression of c-Ret and glial cell line-derived neurotrophic factor receptor alpha-1 mRNAs in response to motor nerve injury in neonate rats

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12 December 2020

Ceramide inhibits cell proliferation through Akt/PKB inactivation and decreases melanin synthesis in Mel-Ab cells

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12 December 2020

The neurotrophin receptors, trkB and p75, differentially regulate motor axonal regeneration

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12 December 2020

The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons.

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12 December 2020

RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2

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12 December 2020

Expression of nerve growth factor receptors by Schwann cells of axotomized peripheral nerves: ultrastructural location, suppression by axonal contact, and binding properties.

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12 December 2020

Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse.

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12 December 2020

An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin.

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12 December 2020

GDNF family neurotrophic factor signaling: four masters, one servant?

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12 December 2020

Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma

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12 December 2020

Shc Binding to Nerve Growth Factor Receptor Is Mediated by the Phosphotyrosine Interaction Domain

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12 December 2020

Kinase suppressor of Ras is ceramide-activated protein kinase

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12 December 2020

Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance.

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12 December 2020

An immunohistochemical study of the nerve growth factor receptor in developing rats

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12 December 2020

The p75 neurotrophin receptor and neuronal apoptosis

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12 December 2020

Receptor recognition by gp130 cytokines

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12 December 2020

Self-reinnervated cat medial gastrocnemius muscles. I. comparisons of the capacity for regenerating nerves to form enlarged motor units after extensive peripheral nerve injuries

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12 December 2020

BDNF and NT-4/5 exert neurotrophic influences on injured adult spinal motor neurons

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12 December 2020

Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor

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12 December 2020

Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo.

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12 December 2020

Motifs of cadherin- and fibronectin type III-related sequences and evolution of the receptor-type-protein tyrosine kinases: sequence similarity between proto-oncogene ret and cadherin family

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12 December 2020

Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons

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12 December 2020

Crystallization and characterization of the high molecular weight form of nerve growth factor (7 S NGF).

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12 December 2020

Alternative expression of Shc family members in nerve-injured motoneurons.

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12 December 2020

Phosphorylation of Raf by ceramide-activated protein kinase

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12 December 2020

Quantitative comparison of the transient rescue effects of neurotrophic factors on axotomized motoneurons in vivo

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12 December 2020

Acetylcholinesterase gene expression in axotomized rat facial motoneurons is differentially regulated by neurotrophins: correlation with trkB and trkC mRNA levels and isoforms.

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12 December 2020

Characterization of a multicomponent receptor for GDNF.

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12 December 2020

Neurotrophin receptor structure and interactions

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12 December 2020

Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons.

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12 December 2020

Dorsal root ganglion neurons require functional neurotrophin receptors for survival during development

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12 December 2020

Truncated trkB receptors on nonneuronal cells inhibit BDNF-induced neurite outgrowth in vitro

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12 December 2020

Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase

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12 December 2020

A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor.

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12 December 2020

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

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12 December 2020

Interleukin-6: structure-function relationships.

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12 December 2020

Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis

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12 December 2020

Synergistic but transient rescue effects of BDNF and GDNF on axotomized neonatal motoneurons

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12 December 2020

The cellular and molecular basis of peripheral nerve regeneration

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12 December 2020

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages

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12 December 2020

Role of neurotrophins in synapse development and plasticity

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12 December 2020

Expression of CNTF/LIF-receptor components and activation of STAT3 signaling in axotomized facial motoneurons: evidence for a sequential postlesional function of the cytokines

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12 December 2020

Decreased synthesis of ciliary neurotrophic factor in degenerating peripheral nerves.

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12 December 2020

A decline in glial cell-line-derived neurotrophic factor expression is associated with impaired regeneration after long-term Schwann cell denervation.

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12 December 2020

Function of PTB domains

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12 December 2020

Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro

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12 December 2020

Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells

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12 December 2020

Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus.

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12 December 2020

Functional receptor for GDNF encoded by the c-ret proto-oncogene

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12 December 2020

Delayed repair of transected nerves: effect of brain-derived neurotrophic factor

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12 December 2020

Influences of neurotrophins on mammalian motoneurons in vivo

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12 December 2020

Repair with collagen tubules linked with brain-derived neurotrophic factor and ciliary neurotrophic factor in a rat sciatic nerve injury model

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12 December 2020

Endogenous BDNF is required for myelination and regeneration of injured sciatic nerve in rodents.

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12 December 2020

Development of the vertebrate neuromuscular junction

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12 December 2020

Enhanced gene expression for phosphatidylinositol 3-kinase in the hypoglossal motoneurons following axonal crush.

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12 December 2020

A Trk nerve growth factor (NGF) receptor point mutation affecting interaction with phospholipase C-gamma 1 abolishes NGF-promoted peripherin induction but not neurite outgrowth

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12 December 2020

Ceramide can induce cell death in sensory neurons, whereas ceramide analogues and sphingosine promote survival

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12 December 2020

Trophic interactions between sensory nerves and their targets

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12 December 2020

Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines.

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12 December 2020

The expression of the low affinity nerve growth factor receptor in long-term denervated Schwann cells

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12 December 2020

Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor

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12 December 2020

Nerve growth factor mediates signal transduction through trk homodimer receptors

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12 December 2020

Peripheral nerve regeneration in interleukin 6-deficient mice

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12 December 2020

Neurotrophins, neurones and peripheral nerve regeneration

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12 December 2020

Association of the p75 neurotrophin receptor with TRAF6

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12 December 2020

Response of facial and rubrospinal neurons to axotomy: changes in mRNA expression for cytoskeletal proteins and GAP-43.

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12 December 2020

GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival

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12 December 2020

Neurotrophin signal transduction in the nervous system

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12 December 2020

p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins

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12 December 2020

Adult mammalian sensory and motor neurons: roles of endogenous neurotrophins and rescue by exogenous neurotrophins after axotomy

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12 December 2020

Neurotrophins and neuronal plasticity

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12 December 2020

Potential roles of gene expression change in adult rat spinal motoneurons following axonal injury: a comparison among c-jun, off-affinity nerve growth factor receptor (LNGFR), and nitric oxide synthase (NOS).

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12 December 2020

Trks: signal transduction and intracellular pathways

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12 December 2020

Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons

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12 December 2020

GDNF triggers a novel ret-independent Src kinase family-coupled signaling via a GPI-linked GDNF receptor alpha1.

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12 December 2020

Neurotrophins and nerve injury in the adult

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12 December 2020

Neurotrophin-6 is a new member of the nerve growth factor family

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12 December 2020

Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons

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12 December 2020

Brain-derived neurotrophic factor and peripheral nerve regeneration: a functional evaluation.

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12 December 2020

Intrinsic programmes of growth and survival in developing vertebrate neurons

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12 December 2020

Glial cell line-derived neurotrophic factor administration in postnatal life results in motor unit enlargement and continuous synaptic remodeling at the neuromuscular junction.

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12 December 2020

The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

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12 December 2020

Sensory impairments and delayed regeneration of sensory axons in interleukin-6-deficient mice

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12 December 2020

Sphingosine 1-phosphate: a ligand for the EDG-1 family of G-protein-coupled receptors

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12 December 2020

The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation

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12 December 2020

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family

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12 December 2020

GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF

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12 December 2020

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

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12 December 2020

Axonal Atrophy from Permanent Peripheral Axotomy in Adult Cat

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12 December 2020

GDNF signalling through the Ret receptor tyrosine kinase

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12 December 2020

Signal transduction by the neurotrophin receptors

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12 December 2020

Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKS): evidence for a divergence of the ERKs and JNKs pathways induced by Ret.

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12 December 2020

Purification and initial characterization of rat B49 glial cell line-derived neurotrophic factor.

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12 December 2020

Intracellular signaling pathways activated by neurotrophic factors

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12 December 2020

The Stat family in cytokine signaling

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12 December 2020

Increased expression of BDNF and trkB mRNA in rat facial motoneurons after axotomy

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12 December 2020

Signal transduction underlying growth cone guidance by diffusible factors

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12 December 2020

BDNF and NT-3 induce intracellular Ca2+ elevation in hippocampal neurones

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12 December 2020

Non-redundant signal transduction of interleukin-6-type cytokines. The adapter protein Shc is specifically recruited to rhe oncostatin M receptor

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12 December 2020

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

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12 December 2020

Nerve growth factor: two receptors, multiple functions

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12 December 2020

p75 neurotrophin receptor as a modulator of survival and death decisions

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12 December 2020

Effects of the neurotrophins nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor (BDNF) on neurite growth from adult sensory neurons in compartmented cultures.

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12 December 2020

Neurotrophins are required for nerve growth during development.

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12 December 2020

Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth

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12 December 2020

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

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12 December 2020

Up-regulation of GDNFR-alpha and c-ret mRNA in facial motor neurons following facial nerve injury in the rat.

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12 December 2020

Synergistic effects of schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1).

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12 December 2020

Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells

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12 December 2020

Signal transduction pathways activated by RET oncoproteins in PC12 pheochromocytoma cells

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12 December 2020

cAMP-induced switching in turning direction of nerve growth cones.

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12 December 2020

Regulation of mRNA expression involved in Ras and PKA signal pathways during rat hypoglossal nerve regeneration

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12 December 2020

Regulation of neurotrophin receptor expression during embryonic and postnatal development.

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12 December 2020

A novel modular mosaic of cell adhesion motifs in the extracellular domains of the neurogenic trk and trkB tyrosine kinase receptors

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12 December 2020

Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations

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12 December 2020

Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo.

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12 December 2020

Interleukin 6 in intact and injured mouse peripheral nerves

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12 December 2020

Role of peripheral nerve extracellular matrix in Schwann cell function and in neurite regeneration

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12 December 2020

The role of ceramide in cell signaling

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12 December 2020

Differential effects of NT-3 on reinnervation of the fast extensor digitorum longus (EDL) and the slow soleus muscle of rat

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12 December 2020

Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival.

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12 December 2020

Central infusions of brain-derived neurotrophic factor and neurotrophin-4/5, but not nerve growth factor and neurotrophin-3, prevent loss of the cholinergic phenotype in injured adult motor neurons.

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12 December 2020

Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130

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12 December 2020

VAMP-1 and VAMP-2 gene expression in rat spinal motoneurones: differential regulation after neuronal injury

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12 December 2020

Life and death decisions: a biological role for the p75 neurotrophin receptor

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12 December 2020

Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

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12 December 2020

Members of several gene families influence survival of rat motoneurons in vitro and in vivo.

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12 December 2020

Functionally antagonistic interactions between the TrkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation.

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12 December 2020

A mathematical model for regeneration rate and initial delay following surgical repair of peripheral nerves.

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12 December 2020

Nerve growth factor-induced process formation by cultured rat pheochromocytoma cells

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12 December 2020

Neurotrophin regulation of the developing nervous system: analyses of knockout mice

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12 December 2020

Critical periods during sensory development

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12 December 2020

Naturally occurring tyrosine kinase inserts block high affinity binding of phospholipase C gamma and Shc to TrkC and neurotrophin-3 signaling

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12 December 2020

A new twist in an old story: the role for crosstalk of neuronal and trophic activity

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12 December 2020

Induction of nerve growth factor receptor in Schwann cells after axotomy

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12 December 2020

The Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cells

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12 December 2020

Interleukin-6 as a neurotrophic factor for promoting the survival of cultured basal forebrain cholinergic neurons from postnatal rats

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12 December 2020

An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathway

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12 December 2020

Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor

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12 December 2020

Neurotrophins: the biological paradox of survival factors eliciting apoptosis

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12 December 2020

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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12 December 2020

Choline acetyltransferase and calcitonin gene-related peptide immunoreactivity in motoneurons after different types of nerve injury

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12 December 2020

Phosphotyrosine residues in the nerve-growth-factor receptor (Trk-A). Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells

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12 December 2020

Neurotrophin signaling via Trks and p75.

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12 December 2020

Rescue of motoneuron and muscle afferent function in cats by regeneration into skin. II. Ia-motoneuron synapse

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12 December 2020

The response of motoneurons to neurotrophins

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12 December 2020

Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFR alpha after sciatic nerve lesion in the mouse

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12 December 2020

Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons

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12 December 2020

Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain

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12 December 2020

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF

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12 December 2020

Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve

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12 December 2020

Neurotrophin-3 delivered locally via fibronectin mats enhances peripheral nerve regeneration.

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12 December 2020

NGF-induced motoneuron cell death depends on the genetic background and motoneuron sub-type

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12 December 2020

Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

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12 December 2020

Developmental changes in the neurotransmitter properties of dissociated sympathetic neurons: a cytochemical study of the effects of medium.

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12 December 2020

High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors.

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12 December 2020

Brain-derived neurotrophic factor and collagen tubulization enhance functional recovery after peripheral nerve transection and repair.

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12 December 2020

Expression of neurotrophins in skeletal muscle: Quantitative comparison and significance for motoneuron survival and maintenance of function

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12 December 2020

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

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12 December 2020

Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration

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12 December 2020

Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.

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12 December 2020

Axotomy induces nerve growth factor receptor immunoreactivity in spinal motor neurons

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12 December 2020

Interleukin-6 and transforming growth factor-beta 1 mRNAs are induced in rat facial nucleus following motoneuron axotomy.

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12 December 2020

Nerve growth factor signaling through p75 induces apoptosis in Schwann cells via a Bcl-2-independent pathway.

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12 December 2020

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells

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12 December 2020

The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma

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12 December 2020

Cardiotrophin-1 requires LIFRbeta to promote survival of mouse motoneurons purified by a novel technique

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12 December 2020

BDNF/NT4-5 receptor TrkB and cadherin participate in cell-cell adhesion

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12 December 2020

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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12 December 2020

Self-reinnervated cat medial gastrocnemius muscles. II. analysis of the mechanisms and significance of fiber type grouping in reinnervated muscles.

1 reference

12 December 2020

Rho GTPases in growth cone guidance

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12 December 2020

Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons

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12 December 2020

Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration

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12 December 2020

Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection

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12 December 2020

Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.

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12 December 2020

Cloning and expression of a novel neurotrophin, NT-7, from carp

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12 December 2020

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy.

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12 December 2020

Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve

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12 December 2020

Increased expression of the alpha subunit of the ciliary neurotrophic factor (CNTF) receptor by rat facial motoneurons after neonatal axotomy and CNTF treatment

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12 December 2020

Hyperinnervation of neuromuscular junctions caused by GDNF overexpression in muscle

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12 December 2020

Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

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12 December 2020

Nerve growth factor and its low-affinity receptor promote Schwann cell migration

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12 December 2020

Neurotrophins: new roles for a seasoned cast

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12 December 2020

Identification of a signaling pathway involved in calcium regulation of BDNF expression.

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12 December 2020

Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor

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12 December 2020

Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation

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12 December 2020

Effect of ciliary neurotrophic factor (CNTF) on motoneuron survival.

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12 December 2020

Nerve growth factor receptor immunoreactivity in neurons of the normal adult rat spinal cord and its modulation after peripheral nerve lesions

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12 December 2020

Neurotrophins and their receptors in nerve injury and repair.

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12 December 2020

Looking at lipid rafts?

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12 December 2020

Identification of Shc docking site on Ret tyrosine kinase

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12 December 2020

Modulation of hippocampal synaptic transmission and plasticity by neurotrophins

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12 December 2020

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

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12 December 2020

Neurotrophins and activity-dependent plasticity

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12 December 2020

Naturally occurring truncated trkB receptors have dominant inhibitory effects on brain-derived neurotrophic factor signaling

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12 December 2020

Improved survival of injured sciatic nerve Schwann cells in mice lacking the p75 receptor

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12 December 2020

Neurotrophin regulation of synaptic transmission

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12 December 2020

Roles of neurotrophins on synaptic development and functions in the central nervous system.

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12 December 2020

Structural determinants of neurotrophin action.

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12 December 2020

Other neurotrophic factors: glial cell line-derived neurotrophic factor (GDNF).

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12 December 2020

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

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12 December 2020

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

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12 December 2020

Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice

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12 December 2020

Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex

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12 December 2020

Reciprocal actions of interleukin-6 and brain-derived neurotrophic factor on rat and mouse primary sensory neurons.

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12 December 2020

Ciliary neurotrophic factor is required for motoneuron sprouting

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12 December 2020

c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.

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12 December 2020

Differential temporal expression of mRNAs for ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), and their receptors (CNTFR alpha, LIFR beta, IL-6R alpha and gp130) in injured peripheral nerves

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12 December 2020

Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro.

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12 December 2020

Expression of growth factor receptors in injured nervous tissue. I. Axotomy leads to a shift in the cellular distribution of specific beta-nerve growth factor binding in the injured and regenerating PNS.

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12 December 2020

Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo

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12 December 2020

Growth factor signaling: where is the specificity?

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12 December 2020

Transducers of life and death: TNF receptor superfamily and associated proteins

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12 December 2020

Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section

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12 December 2020

p75NTR and apoptosis: Trk-dependent and Trk-independent effects

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12 December 2020

The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death

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12 December 2020

Ceramide signaling downstream of the p75 neurotrophin receptor mediates the effects of nerve growth factor on outgrowth of cultured hippocampal neurons.

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12 December 2020

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

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12 December 2020

An immunoglobulin-like domain determines the specificity of neurotrophin receptors.

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12 December 2020

BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth.

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12 December 2020

Peripheral nerve regeneration and neurotrophic factors

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12 December 2020

Minimal effect of CNTF on the ultrastructure of axotomised motoneurones in the adult rat.

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12 December 2020

The intermolecular disulfide bridge of human glial cell line-derived neurotrophic factor: its selective reduction and biological activity of the modified protein

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12 December 2020

Interleukin-6 (IL-6) and its soluble receptor support survival of sensory neurons

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12 December 2020

Differential regulation of trophic factor receptor mRNAs in spinal motoneurons after sciatic nerve transection and ventral root avulsion in the rat.

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12 December 2020

Grb2 binding to the different isoforms of Ret tyrosine kinase.

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12 December 2020

Characterization of the human melanoma nerve growth factor receptor

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12 December 2020

NGF Binding to the trk Tyrosine Kinase Receptor Requires the Extracellular Immunoglobulin-like Domains

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12 December 2020

GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney

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12 December 2020

Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS.

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12 December 2020

Rapid induction of the major embryonic alpha-tubulin mRNA, T alpha 1, during nerve regeneration in adult rats

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12 December 2020

Purification of a new neurotrophic factor from mammalian brain

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12 December 2020

Leukemia inhibitory factor null mice: unhampered in vitro outgrowth of sensory axons but reduced stimulatory potential by nerve segments

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12 December 2020

Rescue of lesioned adult rat spinal motoneurons by adenoviral gene transfer of glial cell line-derived neurotrophic factor

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12 December 2020

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

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12 December 2020

Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures.

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12 December 2020

Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival.

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12 December 2020

Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons

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12 December 2020

Electrical stimulation accelerates and increases expression of BDNF and trkB mRNA in regenerating rat femoral motoneurons.

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12 December 2020

Ciliary neurotrophic factor prevents retrograde neuronal death in the adult central nervous system

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12 December 2020

Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors

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12 December 2020

p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

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12 December 2020

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway

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12 December 2020

The Trk family of neurotrophin receptors

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12 December 2020

Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells

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12 December 2020

Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA

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12 December 2020

Neurotrophin-3-enhanced nerve regeneration selectively improves recovery of muscle fibers expressing myosin heavy chains 2b.

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12 December 2020

Cytokines that signal through the leukemia inhibitory factor receptor-beta complex in the nervous system

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12 December 2020

Neurotrophin receptors: mediators of life and death

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12 December 2020

Permanent rescue of lesioned neonatal motoneurons and enhanced axonal regeneration by adenovirus-mediated expression of glial cell-line-derived neurotrophic factor

1 reference

12 December 2020

Effects of neurotransplants and BDNF on the survival and regeneration of injured adult spinal motoneurons.

1 reference

12 December 2020

TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death.

1 reference

12 December 2020

Proportional enlargement of motor units after partial denervation of cat triceps surae muscles

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12 December 2020

Effects of ciliary neurotrophic factor on retrograde cell reaction after facial nerve crush in young adult rats

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12 December 2020

NGFR-mRNA expression in sciatic nerve: a sensitive indicator of early stages of axonopathy

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12 December 2020

Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling.

1 reference

12 December 2020

Peripheral nerve regeneration in CNTF knockout mice

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12 December 2020

Expression of mRNA for Akt, serine-threonine protein kinase, in the brain during development and its transient enhancement following axotomy of hypoglossal nerve.

1 reference

12 December 2020

Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor.

1 reference

12 December 2020

Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve

1 reference

12 December 2020

Neurotrophins and activity-dependent plasticity of cortical interneurons

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12 December 2020

Persephin, a novel neurotrophic factor related to GDNF and neurturin

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12 December 2020

A function-structure model for NGF-activated TRK

1 reference

12 December 2020

The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase

1 reference

12 December 2020

Biological actions of nerve growth factor in the peripheral nervous system

1 reference

12 December 2020

Role of neurotrophins and trk receptors in the development and maintenance of sensory neurons: an overview

1 reference

12 December 2020

Effects of nerve growth factor on the survival and synaptic function of Ia sensory neurons axotomized in neonatal rats

1 reference

12 December 2020

Inositol trisphosphate and calcium signalling

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12 December 2020

Activation of gp 130 by IL-6/soluble IL-6 receptor induces neuronal differentiation

1 reference

12 December 2020

Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis

1 reference

12 December 2020

The neurotrophin hypothesis for synaptic plasticity.

1 reference

12 December 2020

Brief electrical stimulation promotes the speed and accuracy of motor axonal regeneration

1 reference

12 December 2020

Mechanism of Ret activation by a mutation at aspartic acid 631 identified in sporadic pheochromocytoma

1 reference

12 December 2020

Neuroprotection of spinal motoneurons following targeted transduction with an adenoviral vector carrying the gene for glial cell line-derived neurotrophic factor

1 reference

12 December 2020

Activation loop tyrosines contribute varying roles to TrkB autophosphorylation and signal transduction

1 reference

12 December 2020

Glial cell line-derived neurotrophic factor induces Ret-mediated lamellipodia formation

1 reference

12 December 2020

Guidance of regenerating motor axons in vivo by gradients of diffusible peripheral nerve-derived factors

1 reference

12 December 2020

Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways

1 reference

12 December 2020

Long-term effects of a single dose of brain-derived neurotrophic factor on motoneuron survival following spinal root avulsion in the adult rat

1 reference

12 December 2020

Phosphoinositide 3-kinase regulates crosstalk between Trk A tyrosine kinase and p75(NTR)-dependent sphingolipid signaling pathways

1 reference

12 December 2020

Contributing factors to poor functional recovery after delayed nerve repair: prolonged axotomy

1 reference

12 December 2020

p75NTR: A study in contrasts

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12 December 2020

Axotomy-induced changes in rabbit hindlimb nerves and the effects of chronic electrical stimulation

1 reference

12 December 2020

In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons

1 reference

12 December 2020

Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

1 reference

12 December 2020

Adenoviral vector-mediated GDNF gene transfer prevents death of adult facial motoneurons

1 reference

12 December 2020

GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys.

1 reference

12 December 2020

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

1 reference

12 December 2020

Adult spinal motoneurons remain viable despite prolonged absence of functional synaptic contact with muscle

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12 December 2020

Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

1 reference

12 December 2020

Neurotrophins promote motor neuron survival and are present in embryonic limb bud.

1 reference

12 December 2020

Elevation of ceramide within distal neurites inhibits neurite growth in cultured rat sympathetic neurons

1 reference

12 December 2020

Leukaemia inhibitory factor rescues motoneurones from axotomy-induced cell death

1 reference

12 December 2020

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.

1 reference

12 December 2020

Characterization of glial trkB receptors: differential response to injury in the central and peripheral nervous systems

1 reference

12 December 2020

Identification of Trk binding sites for SHC and phosphatidylinositol 3'-kinase and formation of a multimeric signaling complex

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12 December 2020

Simultaneous treatment with BDNF and CNTF after peripheral nerve transection and repair enhances rate of functional recovery compared with BDNF treatment alone

1 reference

12 December 2020

The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor

1 reference

12 December 2020

p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF

1 reference

12 December 2020

Extended ceramide exposure activates the trkA receptor by increasing receptor homodimer formation

1 reference

12 December 2020

Identifiers

DOI

10.1385/MN:27:3:277

1 reference

Dimensions Publication ID

6 August 2017

1036637537

0 references

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