(Q35180349)

7 August 2017

title

Lysophosphatidic Acid Stimulates the Proliferation of Ovarian Cancer Cells via the gep Proto-Oncogene Gα(12). (English)

1 reference

7 August 2017

1 reference

Zachariah G Goldsmith

1

1 reference

7 August 2017

Ji Hee Ha

2

1 reference

7 August 2017

Muralidharan Jayaraman

3

1 reference

7 August 2017

Danny N Dhanasekaran

4

1 reference

7 August 2017

publication date

1 May 2011

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7 August 2017

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7 August 2017

volume

2

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7 August 2017

issue

5

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7 August 2017

page(s)

563-575

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describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3161422/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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LPA(3), a unique G protein-coupled receptor for lysophosphatidic acid

13 July 2018

1 reference

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Endothelial cells isolated from caveolin-2 knockout mice display higher proliferation rate and cell cycle progression relative to their wild-type counterparts

13 July 2018

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Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells

13 July 2018

1 reference

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G protein regulation of MAPK networks

13 July 2018

1 reference

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The G protein G alpha(13) is required for growth factor-induced cell migration

13 July 2018

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13 July 2018

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Mitogenic signaling by lysophosphatidic acid (LPA) involves Galpha12.

13 July 2018

1 reference

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Galpha13 stimulates cell migration through cortactin-interacting protein Hax-1.

13 July 2018

1 reference

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Cytogenetic and molecular genetic characterization of immortalized human ovarian surface epithelial cell lines: consistent loss of chromosome 13 and amplification of chromosome 20.

13 July 2018

1 reference

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Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer

13 July 2018

1 reference

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Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells

13 July 2018

1 reference

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N-terminal short sequences of alpha subunits of the G12 family determine selective coupling to receptors.

13 July 2018

1 reference

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Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity

13 July 2018

1 reference

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Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

13 July 2018

1 reference

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13 July 2018

1 reference

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Determining cellular role of G alpha 12.

13 July 2018

1 reference

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Advances in the management of epithelial ovarian cancer

13 July 2018

1 reference

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Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells

13 July 2018

1 reference

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13 July 2018

Transforming G proteins

1 reference

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G alpha minigenes expressing C-terminal peptides serve as specific inhibitors of thrombin-mediated endothelial activation

13 July 2018

1 reference

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Constitutive and lysophosphatidic acid (LPA)-induced LPA production: role of phospholipase D and phospholipase A2.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Antagonists of the receptor-G protein interface block Gi-coupled signal transduction.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Cooperative transformation of NIH3T3 cells by G alpha12 and Rac1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Lysophosphatidic acid: G-protein signalling and cellular responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Mutant alpha subunits of G12 and G13 proteins induce neoplastic transformation of Rat-1 fibroblasts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

A putative new growth factor in ascitic fluid from ovarian cancer patients: identification, characterization, and mechanism of action

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Lysophospholipids are potential biomarkers of ovarian cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Alendronate inhibits lysophosphatidic acid-induced migration of human ovarian cancer cells by attenuating the activation of rho.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Direct quantitative analysis of lysophosphatidic acid molecular species by stable isotope dilution electrospray ionization liquid chromatography-mass spectrometry

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Lysophosphatidic acid promotes matrix metalloproteinase (MMP) activation and MMP-dependent invasion in ovarian cancer cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Lysophospholipids activate ovarian and breast cancer cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161422

Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21901169

12 December 2020

inferred from PubMed ID database lookup

Electrospray ionization mass spectrometry analysis of lysophospholipids in human ascitic fluids: comparison of the lysophospholipid contents in malignant vs nonmalignant ascitic fluids

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21901169

12 December 2020

inferred from PubMed ID database lookup

Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21901169

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1177/1947601911419362

1 reference

7 August 2017

1 reference

7 August 2017

1 reference