(Q35183997)

7 August 2017

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title

Drug development for asthma (English)

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7 August 2017

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1

Michael J Holtzman

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7 August 2017

1 August 2003

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American Journal of Respiratory Cell and Molecular Biology

7 August 2017

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7 August 2017

29

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7 August 2017

163-171

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7 August 2017

2

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Immunity, inflammation, and remodeling in the airway epithelial barrier: epithelial-viral-allergic paradigm

7 August 2017

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Modulation of vasodilator-stimulated phosphoprotein in vivo in human epithelial cells by segmental allergen challenge and beta2-agonist therapy

21 January 2018

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Effect of combining salmeterol and fluticasone on the progression of airway remodeling

21 January 2018

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Modulation of T-cell function by (R)- and (S)-isomers of albuterol: anti-inflammatory influences of (R)-isomers are negated in the presence of the (S)-isomer

21 January 2018

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Bronchial hyperresponsiveness induced by chronic treatment with albuterol: Role of sensory nerves.

21 January 2018

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Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

21 January 2018

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Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1: potential use of hypoallergenic isoforms for immunotherapy

21 January 2018

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Four recombinant isoforms of Cor a I, the major allergen of hazel pollen, show different IgE-binding properties

21 January 2018

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Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions

21 January 2018

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Gene vaccination: plasmid DNA is more than just a blueprint

21 January 2018

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Nucleic acid immunization: concepts and techniques associated with third generation vaccines

21 January 2018

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Comparison of numerous delivery systems for the induction of cytotoxic T lymphocytes by immunization.

21 January 2018

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Oral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergy.

21 January 2018

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Ragweed immunotherapy in adult asthma

21 January 2018

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The effect of infections on susceptibility to autoimmune and allergic diseases

21 January 2018

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Environmental exposure to endotoxin and its relation to asthma in school-age children

21 January 2018

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Immunostimulatory DNA for asthma: better than eating dirt

21 January 2018

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Oligonucleotide adjuvants for T helper 1 (Th1)-specific vaccination

21 January 2018

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CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity

21 January 2018

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The one-two of T helper cells: does interferon-gamma knock out the Th2 hypothesis for asthma?

21 January 2018

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Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma

21 January 2018

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Interleukin 12 p40 production by barrier epithelial cells during airway inflammation

21 January 2018

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Antigen-nonspecific recruitment of Th2 cells to the lung as a mechanism for viral infection-induced allergic asthma

21 January 2018

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Treatment of allergic asthma with monoclonal anti-IgE antibody. rhuMAb-E25 Study Group.

21 January 2018

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Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma

21 January 2018

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Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma

21 January 2018

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Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial.

21 January 2018

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Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

21 January 2018

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Activated, cytotoxic CD8(+) T lymphocytes contribute to the pathology of asthma death

21 January 2018

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Allergen-specific CD8(+) T cells and atopic disease

21 January 2018

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Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

21 January 2018

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Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway.

21 January 2018

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Decoy receptors in the regulation of T helper cell type 2 responses

21 January 2018

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Interleukin-13: central mediator of allergic asthma

21 January 2018

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Interleukin-9 induces mucous cell metaplasia independent of inflammation

21 January 2018

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Viral induction of a chronic asthma phenotype and genetic segregation from the acute response

21 January 2018

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Cytokine traps: multi-component, high-affinity blockers of cytokine action

21 January 2018

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CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation

21 January 2018

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The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness

21 January 2018

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The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics

21 January 2018

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CCR3: a key to mast cell phenotypic and functional diversity?

21 January 2018

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A controlled trial of natalizumab for relapsing multiple sclerosis.

21 January 2018

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Cutting edge: agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2

21 January 2018

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Mast-cell infiltration of airway smooth muscle in asthma.

21 January 2018

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Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

21 January 2018

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Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

21 January 2018

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Patterns for RANTES secretion and intercellular adhesion molecule 1 expression mediate transepithelial T cell traffic based on analyses in vitro and in vivo

21 January 2018

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CD28 and CTLA4 coordinately regulate airway inflammatory cell recruitment and T-helper cell differentiation after inhaled allergen

21 January 2018

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A role for the C3a anaphylatoxin receptor in the effector phase of asthma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1165/RCMB.F276

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7 August 2017

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PubMed ID

12878583