(Q35188897)

7 August 2017

title

Deletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic response (English)

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7 August 2017

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8

K E Bachman

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author name string

M B Weiss

1

1 reference

7 August 2017

M I Vitolo

2

1 reference

7 August 2017

M Mohseni

3

1 reference

7 August 2017

D M Rosen

4

1 reference

7 August 2017

S R Denmeade

5

1 reference

7 August 2017

B H Park

6

1 reference

7 August 2017

D J Weber

7

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7 August 2017

language of work or name

English

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publication date

21 June 2010

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7 August 2017

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7 August 2017

volume

29

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7 August 2017

issue

33

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7 August 2017

page(s)

4715-4724

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describes a project that uses

7 August 2017

MCF-10A TP53(-/-)

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cites work

Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells

1 reference

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Knockin of mutant PIK3CA activates multiple oncogenic pathways

28 July 2018

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Transcriptional control of human p53-regulated genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

A comparison of DNA copy number profiling platforms

28 July 2018

1 reference

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Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation

28 July 2018

1 reference

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Coping with stress: multiple ways to activate p53.

28 July 2018

1 reference

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Single nucleotide polymorphism array analysis of cancer.

28 July 2018

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Autocrine and juxtacrine effects of amphiregulin on the proliferative, invasive, and migratory properties of normal and neoplastic human mammary epithelial cells

28 July 2018

1 reference

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Notch3 gene amplification in ovarian cancer

28 July 2018

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Cigarette smoke condensate-induced transformation of normal human breast epithelial cells in vitro

28 July 2018

1 reference

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28 July 2018

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DNA copy number changes in young gastric cancer patients with special reference to chromosome 19.

28 July 2018

1 reference

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H-ras, but not N-ras, induces an invasive phenotype in human breast epithelial cells: a role for MMP-2 in the H-ras-induced invasive phenotype

28 July 2018

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

28 July 2018

1 reference

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Regulation of p53 downstream genes.

28 July 2018

1 reference

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Clinical implications of p53 mutations

28 July 2018

1 reference

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The dual role model for p53 in maintaining genomic integrity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

p53 mutations and DNA ploidy in colorectal adenocarcinomas.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

p53 nuclear immunoreactivity as a predictor of response and outcome following chemotherapy for metastatic bladder cancer

28 July 2018

1 reference

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Original p53 status predicts for pathological response in locally advanced breast cancer patients treated preoperatively with continuous infusion 5-fluorouracil and radiation therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Abnormal centrosome amplification in the absence of p53.

28 July 2018

1 reference

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Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

28 July 2018

1 reference

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Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Astrocytes derived from p53-deficient mice provide a multistep in vitro model for development of malignant gliomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

p53 mutations in human cancers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

KRAS, p53 and BRAF gene mutations and aneuploidy in sporadic colorectal cancer progression.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

p21(WAF1/CIP1) mediates the growth response to TGF-beta in human epithelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Chromosome arm 20q gains and other genomic alterations in colorectal cancer metastatic to liver, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Impact of DNA amplification on gene expression patterns in breast cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Randomized Trial of Dose-Dense Versus Conventionally Scheduled and Sequential Versus Concurrent Combination Chemotherapy as Postoperative Adjuvant Treatment of Node-Positive Primary Breast Cancer: First Report of Intergroup Trial C9741/Cancer and Leu

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164558

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

15 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.220

Assessments of clonal composition of colorectal adenomas by FISH analysis of chromosomes 1, 7, 13 and 20

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.220

Genomic convergence and suppression of centrosome hyperamplification in primary p53-/- cells in prolonged culture

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.220

Genomic instability and apoptosis are frequent in p53 deficient young mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.220

Molecular Genetic Studies of Tumor suppressor Gene Regions on chromosomes 13 and 17 in Colorectal Tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.220

Sporadic amplification of the insulin receptor gene in human breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.220

No significant predictive value of c-erbB-2 or p53 expression regarding sensitivity to primary chemotherapy or radiotherapy in breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.220

Relationship of gene expression and chromosomal abnormalities in colorectal cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.220

Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20562907

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Targeted inactivation of p53 in human cells does not result in aneuploidy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20562907

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Somatic p53 mutations in human breast carcinomas in an Icelandic population: a prognostic factor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20562907

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2010.220

1 reference

7 August 2017

1 reference

7 August 2017

1 reference