(Q35192146)

7 August 2017

title

Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging (English)

1 reference

7 August 2017

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9

Ana Maria Cuervo

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Laura Santambrogio

8

object named as

Laura Santambrogio

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Joan Villarroya

object named as

Joan Villarroya

2

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Francesc Villarroya

object named as

Francesc Villarroya

7

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author name string

Jaime L Schneider

1

1 reference

7 August 2017

Antonio Diaz-Carretero

3

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7 August 2017

Bindi Patel

4

1 reference

7 August 2017

Aleksandra M Urbanska

5

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7 August 2017

Mia M Thi

6

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7 August 2017

publication date

23 January 2015

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7 August 2017

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7 August 2017

volume

14

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7 August 2017

issue

2

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7 August 2017

page(s)

249-264

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Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation

7 August 2017

cites work

1 reference

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13 July 2018

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13 July 2018

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Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation

13 July 2018

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13 July 2018

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Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver

13 July 2018

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Aging modulates susceptibility to mouse liver Mallory-Denk body formation

13 July 2018

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Inhibitory effect of dietary lipids on chaperone-mediated autophagy

13 July 2018

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Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease

13 July 2018

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Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose

13 July 2018

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A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

13 July 2018

1 reference

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TFEB links autophagy to lysosomal biogenesis

13 July 2018

1 reference

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Autophagy-deficient mice develop multiple liver tumors

13 July 2018

1 reference

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Altered lipid content inhibits autophagic vesicular fusion

13 July 2018

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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

13 July 2018

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Mammalian autophagy: core molecular machinery and signaling regulation

13 July 2018

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Chaperone-mediated autophagy: selectivity pays off.

13 July 2018

1 reference

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Autophagy regulates lipid metabolism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

13 July 2018

1 reference

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Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

13 July 2018

1 reference

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The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane

13 July 2018

1 reference

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Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy

13 July 2018

1 reference

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Alterations in xenobiotic metabolism in the long-lived Little mice

13 July 2018

1 reference

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Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Consequences of the selective blockage of chaperone-mediated autophagy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

FGF-21 as a novel metabolic regulator

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Activation of chaperone-mediated autophagy during oxidative stress

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Selective uptake and degradation of c-Fos and v-Fos by rat liver lysosomes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

A receptor for the selective uptake and degradation of proteins by lysosomes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Degradation of proteasomes by lysosomes in rat liver.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Peptide sequences that target cytosolic proteins for lysosomal proteolysis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Isolation of subcellular organelles

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

Altered dynamics of the lysosomal receptor for chaperone-mediated autophagy with age.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364837

27 September 2018

Identifiers

DOI

10.1111/ACEL.12310

1 reference

7 August 2017

1 reference

7 August 2017

1 reference