(Q35196538)

7 August 2017

1 reference

title

NF-kappaB in pancreatic cancer (English)

1 reference

7 August 2017

0 references

1 reference

Guido M Sclabas

1

1 reference

7 August 2017

Shuichi Fujioka

2

1 reference

7 August 2017

Christian Schmidt

3

1 reference

7 August 2017

Douglas B Evans

4

1 reference

7 August 2017

Paul J Chiao

5

1 reference

7 August 2017

publication date

1 January 2003

1 reference

International Journal of Gastrointestinal Cancer

7 August 2017

published in

1 reference

7 August 2017

volume

33

1 reference

7 August 2017

issue

1

1 reference

7 August 2017

page(s)

15-26

1 reference

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

7 August 2017

cites work

1 reference

12 December 2020

Structure of an IkappaBalpha/NF-kappaB complex

1 reference

12 December 2020

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas

1 reference

12 December 2020

NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control

1 reference

12 December 2020

Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas : a new marker of DPC4 inactivation

1 reference

12 December 2020

Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced NF kappa B activation

1 reference

12 December 2020

[Transcription factor NF-kappa B/RelA are constitutively activated and localized in the cell nuclei of E1A + cHa-Ras transformants]

1 reference

12 December 2020

The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells

1 reference

12 December 2020

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

12 December 2020

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

12 December 2020

The EGF receptor family as targets for cancer therapy

1 reference

12 December 2020

An essential role for nuclear factor kappa B in preventing TNF-alpha-induced cell death in prostate cancer cells

1 reference

12 December 2020

Control of apoptosis by Rel/NF-kappaB transcription factors

1 reference

12 December 2020

The essential role of MEKK3 in TNF-induced NF-kappaB activation

1 reference

12 December 2020

Activation of oncogenicity of the c-rel proto-oncogene

1 reference

12 December 2020

The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis

1 reference

12 December 2020

Induction of apoptosis of cytokine-producing bladder cancer cells by adenovirus-mediated IkappaBalpha overexpression

1 reference

12 December 2020

Identification and characterization of an IkappaB kinase

1 reference

12 December 2020

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

1 reference

12 December 2020

Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

1 reference

12 December 2020

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

1 reference

12 December 2020

Genetic progression in the pancreatic ducts

1 reference

12 December 2020

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

1 reference

12 December 2020

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

12 December 2020

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

1 reference

12 December 2020

Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells.

1 reference

12 December 2020

The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes

1 reference

12 December 2020

Mapping of a serine-rich domain essential for the transcriptional, antiapoptotic, and transforming activities of the v-Rel oncoprotein

1 reference

12 December 2020

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

12 December 2020

Constitutive IkappaB kinase activity correlates with nuclear factor-kappaB activation in human melanoma cells

1 reference

12 December 2020

Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses

1 reference

12 December 2020

Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines

1 reference

12 December 2020

Redox-sensitive transactivation of epidermal growth factor receptor by tumor necrosis factor confers the NF-kappa B activation.

1 reference

12 December 2020

Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness

1 reference

12 December 2020

Biphasic regulation of NF-kappa B activity underlies the pro- and anti-inflammatory actions of nitric oxide.

1 reference

12 December 2020

Regulation of NF-kappaB activity by I kappaB-related proteins in adenocarcinoma cells

1 reference

12 December 2020

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

12 December 2020

Transcriptional regulation of the bcl-x gene encoding the anti-apoptotic Bcl-xL protein by Ets, Rel/NFkappaB, STAT and AP1 transcription factor families

1 reference

12 December 2020

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

1 reference

12 December 2020

Gene transfer for angiogenesis in coronary artery disease.

1 reference

12 December 2020

Structure, regulation and function of NF-kappa B

1 reference

12 December 2020

The Hallmarks of Cancer

1 reference

12 December 2020

Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation

1 reference

12 December 2020

Inhibition of NF kappa B activation by pyrrolidine dithiocarbamate prevents in vivo hypoxia/reoxygenation-mediated myocardial angiogenesis.

1 reference

12 December 2020

Defective IkappaBalpha in Hodgkin cell lines with constitutively active NF-kappaB.

1 reference

12 December 2020

Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells

1 reference

12 December 2020

Epidermal growth factor activation of NF-kappaB is mediated through IkappaBalpha degradation and intracellular free calcium

1 reference

12 December 2020

Autoregulation of I kappa B alpha activity

1 reference

12 December 2020

Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization

1 reference

12 December 2020

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1 reference

12 December 2020

Pathways of apoptosis in lymphocyte development, homeostasis, and disease

1 reference

12 December 2020

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

12 December 2020

Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

1 reference

12 December 2020

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

1 reference

12 December 2020

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1 reference

12 December 2020

In vivo control of NF-kappa B activation by I kappa B alpha.

1 reference

12 December 2020

Altered expression of the p50 subunit of the NF-kappa B transcription factor complex in non-small cell lung carcinoma

1 reference

12 December 2020

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

1 reference

12 December 2020

Focus on pancreas cancer

1 reference

12 December 2020

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1 reference

12 December 2020

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

12 December 2020

Molecular pathology of pancreatic cancer

1 reference

12 December 2020

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

1 reference

12 December 2020

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

1 reference

12 December 2020

Constitutive nuclear NF kappa B/rel DNA-binding activity of rat thymocytes is increased by stimuli that promote apoptosis, but not inhibited by pyrrolidine dithiocarbamate

1 reference

12 December 2020

Bryostatin 1 induces differentiation and potentiates the antitumor effect of Auristatin PE in a human pancreatic tumor (PANC-1) xenograft model

1 reference

12 December 2020

Activation of NF-kappaB/Rel occurs early during neoplastic transformation of mammary cells

1 reference

12 December 2020

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

12 December 2020

The expanding role of mitochondria in apoptosis

1 reference

12 December 2020

Reactive oxygen and NF-kappaB in VEGF-induced migration of human vascular smooth muscle cells.

1 reference

12 December 2020

Bcl-2 suppresses apoptosis resulting from disruption of the NF-kappa B survival pathway

1 reference

12 December 2020

Function of nuclear factor kappaB in pancreatic cancer metastasis

1 reference

12 December 2020

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

1 reference

12 December 2020

NF-kappa B: ten years after

1 reference

12 December 2020

Multiple hemopoietic defects and lymphoid hyperplasia in mice lacking the transcriptional activation domain of the c-Rel protein

1 reference

12 December 2020

Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice

1 reference

12 December 2020

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

1 reference

12 December 2020

Progression model for pancreatic cancer.

1 reference

12 December 2020

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

12 December 2020

ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein

1 reference

12 December 2020

Alteration of integrins by interleukin-1alpha in human pancreatic cancer cells

1 reference

12 December 2020

Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFkappaB p65 protein expression.

1 reference

12 December 2020

Phorbol ester reduces constitutive nuclear NF kappa B and inhibits HIV-1 production in mature human monocytic cells

1 reference

12 December 2020

NF-kappaB regulation in the immune system

1 reference

12 December 2020

Mechanism for biphasic rel A. NF-kappaB1 nuclear translocation in tumor necrosis factor alpha-stimulated hepatocytes

1 reference

12 December 2020

Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines

1 reference

12 December 2020

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

12 December 2020

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

12 December 2020

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

1 reference

12 December 2020

Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations

1 reference

12 December 2020

Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA

1 reference

12 December 2020

Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

1 reference

12 December 2020

Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate

1 reference

12 December 2020

Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappaB signal pathways.

1 reference

12 December 2020

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

12 December 2020

Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis.

1 reference

12 December 2020

Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells

1 reference

12 December 2020

Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.

1 reference

12 December 2020

Hypoxia/reoxygenation promotes myocardial angiogenesis via an NF kappa B-dependent mechanism in a rat model of chronic myocardial infarction

1 reference

12 December 2020

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1 reference

12 December 2020

The epidermal growth factor receptor associates with and recruits phosphatidylinositol 3-kinase to the platelet-derived growth factor beta receptor

1 reference

12 December 2020

Raf-induced transformation requires an interleukin 1 autocrine loop.

1 reference

12 December 2020

Elevated constitutive IkappaB kinase activity and IkappaB-alpha phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-alpha transcription

1 reference

12 December 2020

Specificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and intercellular adhesion molecule-1 up-regulation

1 reference

12 December 2020

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

1 reference

12 December 2020

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

12 December 2020

Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.

1 reference

12 December 2020

The IKK-2/Ikappa Balpha /NF-kappa B pathway plays a key role in the regulation of CCR3 and eotaxin-1 in fibroblasts. A critical link to dermatitis in Ikappa Balpha -deficient mice

1 reference

12 December 2020

Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer

1 reference

12 December 2020

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

12 December 2020

The Rel/NF-kappaB signal transduction pathway: introduction

1 reference

12 December 2020

v-Rel prevents apoptosis in transformed lymphoid cells and blocks TNFalpha-induced cell death

1 reference

12 December 2020

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

1 reference

12 December 2020

Angiogenesis and tumor metastasis

1 reference

12 December 2020

PRAD1/cyclin D1 proto-oncogene: genomic organization, 5' DNA sequence, and sequence of a tumor-specific rearrangement breakpoint

1 reference

12 December 2020

The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

1 reference

12 December 2020

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

1 reference

12 December 2020

The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines

1 reference

12 December 2020

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

1 reference

12 December 2020

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

12 December 2020

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

1 reference

12 December 2020

Antioxidants inhibit cytokine production and suppress NF-kappaB activation in CAPAN-1 and CAPAN-2 cell lines

1 reference

12 December 2020

Effect of antisense oligodeoxynucleotide directed to NF-kappa B-RelA on Bcl-XL mRNA in extended drug resistance leukemia cell line HL-60/E6.

1 reference

12 December 2020

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

12 December 2020

Adenovirus type 5 E1A gene products act as transformation suppressors of the neu oncogene

1 reference

12 December 2020

Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis

1 reference

12 December 2020

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

1 reference

12 December 2020

Destabilizing influences in apoptosis: sowing the seeds of IAP destruction

1 reference

12 December 2020

Mechanisms of constitutive NF-kappaB activation in human prostate cancer cells

1 reference

12 December 2020

Enhanced VEGF production and decreased immunogenicity induced by TGF-beta 1 promote liver metastasis of pancreatic cancer

1 reference

12 December 2020

Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

1 reference

12 December 2020

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

1 reference

12 December 2020

1 reference

12 December 2020

Transformation of avian lymphoid cells by reticuloendotheliosis virus

1 reference

12 December 2020

VEGF as a mediator of tumor-associated immunodeficiency

1 reference

12 December 2020

The v-Rel oncoprotein blocks apoptosis and proteolysis of I kappa B-alpha in transformed chicken spleen cells

1 reference

12 December 2020

Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements

1 reference

12 December 2020

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

1 reference

12 December 2020

Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin

1 reference

12 December 2020

A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells

1 reference

12 December 2020

Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha

1 reference

12 December 2020

Negative regulation of transactivation function but not DNA binding of NF-kappaB and AP-1 by IkappaBbeta1 in breast cancer cells

1 reference

12 December 2020

Epidermal growth factor-related peptides and their receptors in human malignancies

1 reference

12 December 2020

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

1 reference

12 December 2020

The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome

1 reference

12 December 2020

Missing pieces in the NF-kappaB puzzle

1 reference

12 December 2020

Oxidative stress due to hypoxia/reoxygenation induces angiogenic factor VEGF in adult rat myocardium: possible role of NFkappaB.

1 reference

12 December 2020

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

12 December 2020

Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase

1 reference

12 December 2020

Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis

1 reference

12 December 2020

NF-kappa B is induced in the nuclei of cultured rat aortic smooth muscle cells by stimulation of various growth factors

1 reference

12 December 2020

The c-erb B-2 proto-oncogene in human pancreatic cancer

1 reference

12 December 2020

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

1 reference

12 December 2020

Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts.

1 reference

12 December 2020

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

12 December 2020

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

1 reference

12 December 2020

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

1 reference

12 December 2020

Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface:impact on human pancreatic carcinoma cell growth by autocrine regulation

1 reference

12 December 2020

Clinicopathological significance of epidermal growth factor and its receptor in human pancreatic cancer

1 reference

12 December 2020

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

1 reference

12 December 2020

Apoptosis: a link between cancer genetics and chemotherapy

1 reference

12 December 2020

Identifiers

DOI

10.1385/IJGC:33:1:15

1 reference

release_ia2scnhi6reenkmsfohilna5iu

7 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ia2scnhi6reenkmsfohilna5iu

24 November 2022

mapped directly with Wikidata item

1 reference