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Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
title
Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
main subject
lung cancer
1 reference
based on heuristic
inferred from title
author
Artur Zajkowicz
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
Dorota Butkiewicz
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
Rafal Suwinski
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
Marek Rusin
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
author name string
A Drosik
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
M Giglok
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
language of work or name
English
0 references
publication date
17 March 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
published in
British Journal of Cancer
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
volume
112
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
issue
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
page(s)
1114-1120
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
copyright license
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International
start time
1 March 2015
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Li-Fraumeni syndrome: cancer risk assessment and clinical management
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Nutlin-3a, an MDM2 antagonist and p53 activator, helps to preserve the replicative potential of cancer cells treated with a genotoxic dose of resveratrol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Modes of p53 regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Mechanisms of therapy-related carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
ATM and related protein kinases: safeguarding genome integrity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
p53 protein accumulation in addition to the transactivation activity is required for p53-dependent cell cycle arrest after treatment of cells with camptothecin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Enhanced phosphorylation of p53 by ATM in response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
A functional p53-responsive intronic promoter is contained within the humanmdm2gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
Suppression of human colorectal carcinoma cell growth by wild-type p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
13 July 2018
PPM1D mutations in circulating white blood cells and the risk for ovarian cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366904
retrieved
26 September 2018
A novel form of Epstein-Barr virus latency in normal B cells in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FBJC.2015.79
retrieved
21 January 2018
Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25742468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25742468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
p53 phosphorylation mutants retain transcription activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25742468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/BJC.2015.79
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PMC publication ID
4366904
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PubMed publication ID
25742468
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25742468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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