(Q35206874)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

review article

1 reference

title

The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

author name string

Klaus Strebel

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

publication date

1 September 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

published in

Microbes and Infection

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

1029-1039

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

Cell-free transmission of Vif mutants of HIV-1

7 November 2019

cites work

1 reference

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7 January 2021

A novel gene of HIV-1, vpu, and its 16-kilodalton product

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

HIV accessory proteins: multifunctional components of a complex system.

1 reference

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7 January 2021

Genetic organization of a chimpanzee lentivirus related to HIV-1.

1 reference

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7 January 2021

Characterization of a novel simian immunodeficiency virus with a vpu gene from greater spot-nosed monkeys (Cercopithecus nictitans) provides new insights into simian/human immunodeficiency virus phylogeny

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Human immunodeficiency virus type 2 glycoprotein enhancement of particle budding: role of the cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The envelope glycoprotein of human immunodeficiency virus type 2 enhances viral particle release: a Vpu-like factor?

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Identification of a protein encoded by the vpu gene of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Solution structure of the cytoplasmic domain of the human immunodeficiency virus type 1 encoded virus protein U (Vpu).

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Solution structure of the hydrophilic region of HIV-1 encoded virus protein U (Vpu) by CD and lH NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Secondary structure and tertiary fold of the human immunodeficiency virus protein U (Vpu) cytoplasmic domain in solution

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Correlation of the structural and functional domains in the membrane protein Vpu from HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Solution structure and orientation of the transmembrane anchor domain of the HIV-1-encoded virus protein U by high-resolution and solid-state NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Membrane interactions and alignment of structures within the HIV-1 Vpu cytoplasmic domain: effect of phosphorylation of serines 52 and 56

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

HIV-1 encoded virus protein U (Vpu) solution structure of the 41-62 hydrophilic region containing the phosphorylated sites Ser52 and Ser56.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Blockade of human immunodeficiency virus type 1 production in CD4+ T cells by an intracellular CD4 expressed under control of the viral long terminal repeat

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Prevention of HIV-1 glycoprotein transport by soluble CD4 retained in the endoplasmic reticulum.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Degradation of CD4 induced by human immunodeficiency virus type 1 Vpu protein: a predicted alpha-helix structure in the proximal cytoplasmic region of CD4 contributes to Vpu sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein are regulated by phosphorylation and occur in different cellular compartments

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Phosphorylation of both phosphoacceptor sites in the HIV-1 Vpu cytoplasmic domain is essential for Vpu-mediated ER degradation of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The ancient regulatory-protein family of WD-repeat proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Rapid degradation of CD4 in cells expressing human immunodeficiency virus type 1 Env and Vpu is blocked by proteasome inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Protein degradation or regulation: Ub the judge

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Control of apoptosis by Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Functional role of human immunodeficiency virus type 1 vpu.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Functional analysis of the phosphorylation sites on the human immunodeficiency virus type 1 Vpu protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Association of Vpu-binding protein with microtubules and Vpu-dependent redistribution of HIV-1 Gag protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Viral protein U (Vpu)-mediated enhancement of human immunodeficiency virus type 1 particle release depends on the rate of cellular proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Effects of Vpu expression on Xenopus oocyte membrane conductance

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Simulation of the HIV-1 Vpu transmembrane domain as a pentameric bundle

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Ion channels formed by HIV-1 Vpu: a modelling and simulation study

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Lack of effect of cytoplasmic tail truncations on human immunodeficiency virus type 2 ROD env particle release activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Molecular cloning and polymorphism of the human immune deficiency virus type 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Naturally occurring amino acid substitutions in the HIV-2 ROD envelope glycoprotein regulate its ability to augment viral particle release.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Comparison of Vpu sequences from diverse geographical isolates of HIV type 1 identifies the presence of highly variable domains, additional invariant amino acids, and a signature sequence motif common to subtype C isolates

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

The Antibody Response to the HIV-1 Specific "Out" (vpu) Protein: Identification of an Immunodominant Epitope and Correlation of Antibody Detectability to Clinical Stages

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

HIV-1 Vpu represents a minor target for cytotoxic T lymphocytes in HIV-1-infection

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Clustering patterns of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1 (HIV-1) proteins reveal imprints of immune evasion on HIV-1 global variation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

A cell-free stock of simian-human immunodeficiency virus that causes AIDS in pig-tailed macaques has a limited number of amino acid substitutions in both SIVmac and HIV-1 regions of the genome and has offered cytotropism

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Chronology of genetic changes in the vpu, env, and Nef genes of chimeric simian-human immunodeficiency virus (strain HXB2) during acquisition of virulence for pig-tailed macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Presence of Intact vpu and nef genes in nonpathogenic SHIV is essential for acquisition of pathogenicity of this virus by serial passage in macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Deletion of the vpu sequences prior to the env in a simian-human immunodeficiency virus results in enhanced Env precursor synthesis but is less pathogenic for pig-tailed macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

A molecular clone of simian-human immunodeficiency virus (DeltavpuSHIV(KU-1bMC33)) with a truncated, non-membrane-bound vpu results in rapid CD4(+) T cell loss and neuro-AIDS in pig-tailed macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

A simian human immunodeficiency virus with a nonfunctional Vpu (deltavpuSHIV(KU-1bMC33)) isolated from a macaque with neuroAIDS has selected for mutations in env and nef that contributed to its pathogenic phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Cell surface CD4 inhibits HIV-1 particle release by interfering with Vpu activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

Molecular dynamics investigation of membrane-bound bundles of the channel-forming transmembrane domain of viral protein U from the human immunodeficiency virus HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900191-6

7 January 2021

10.1016/S1286-4579(03)00191-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference