(Q40816820)

English

The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.

scientific article published on 16 February 2001

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278695%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278695%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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6 November 2019

1

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6 November 2019

author name string

C Perrin

2

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6 November 2019

K Strebel

4

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6 November 2019

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16 February 2001

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6 November 2019

Journal of Biological Chemistry

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6 November 2019

276

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6 November 2019

19

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6 November 2019

15920-15928

1 reference

Europe PubMed Central

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6 November 2019

HIV accessory proteins: multifunctional components of a complex system.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Rapid degradation of CD4 in cells expressing human immunodeficiency virus type 1 Env and Vpu is blocked by proteasome inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

SCF and Cullin/Ring H2-based ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Control of apoptosis by Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

NF-kappaB activation and HIV-1 induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

The HIV 'A' (sor) gene product is essential for virus infectivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

The human immunodeficiency virus type 1 Vpu protein tethered to the CD4 extracellular domain is localized to the plasma membrane and is biologically active in the secretory pathway of mammalian cells: implications for the mechanisms of Vpu function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

A soluble form of CD4 (T4) protein inhibits AIDS virus infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Cell surface CD4 inhibits HIV-1 particle release by interfering with Vpu activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Nuclear IkappaBbeta maintains persistent NF-kappaB activation in HIV-1-infected myeloid cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Host factors in the pathogenesis of HIV disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Lymphocyte responses and cytokines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Activation of transcription factors NF-kappaB and NF-IL-6 by human immunodeficiency virus type 1 protein R (Vpr) induces interleukin-8 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

A TH1-->TH2 switch is a critical step in the etiology of HIV infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Limiting dilution analysis of interleukin-2-producing T cells responsive to recall and alloantigens in human immunodeficiency virus-infected and uninfected individuals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

HIV transcriptional activation by the accessory protein, VPR, is mediated by the p300 co-activator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Extracellular HIV type 1 Tat protein induces CD69 expression through NF-kappaB activation: possible correlation with cell surface Tat-binding proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

An intact NF-kappa B signaling pathway is required for maintenance of mature B cell subsets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Interaction between the Cytoplasmic Domains of HIV-1 Vpu and CD4: Role of Vpu Residues Involved in CD4 Interaction andin VitroCD4 Degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010533200

21 January 2018

Identifiers

10.1074/JBC.M010533200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278695%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278695%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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