(Q35208466)

7 August 2017

1 reference

title

Intrabody and intrakine strategies for molecular therapy (English)

1 reference

7 August 2017

Yurong Yang Wheeler

1

1 reference

PubMed ID

12946308

7 August 2017

Si-Yi Chen

series ordinal

2

1 reference

PubMed ID

12946308

7 August 2017

David C Sane

series ordinal

3

1 reference

7 August 2017

1 September 2003

1 reference

7 August 2017

1 reference

7 August 2017

8

1 reference

7 August 2017

3

1 reference

7 August 2017

355-366

1 reference

Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins

7 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Regulation of protein export from the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Quality control of ER synthesized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

ER quality control: the cytoplasmic connection

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

A comparison of strategies to stabilize immunoglobulin Fv-fragments

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Single-chain antigen-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

A recombinant immunotoxin containing a disulfide-stabilized Fv fragment

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

A new means of inducibly inactivating a cellular protein

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intracellular antibodies as a new class of therapeutic molecules for gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

A C-terminal signal prevents secretion of luminal ER proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Sequence of a second human KDEL receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

A human homologue of the yeast HDEL receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Extralysosomal protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Degradation of a mutant secretory protein, alpha1-antitrypsin Z, in the endoplasmic reticulum requires proteasome activity

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Human immunodeficiency viruses and the pathogenesis of AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Identification of a major co-receptor for primary isolates of HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intrakines--evidence for a trans-cellular mechanism of action

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Inactivation of HIV-1 chemokine co-receptor CXCR-4 by a novel intrakine strategy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Anti-HIV type 1 activity of wild-type and functional defective RANTES intrakine in primary human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Phenotypic knockout of HIV type 1 chemokine coreceptor CCR-5 by intrakines as potential therapeutic approach for HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Inhibition of human immunodeficiency virus type 1 replication in vitro in acutely and persistently infected human CD4+ mononuclear cells expressing murine and humanized anti-human immunodeficiency virus type 1 Tat single-chain variable fragment intr

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Human anti-HIV-1 tat sFv intrabodies for gene therapy of advanced HIV-1-infection and AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Inhibition of human immunodeficiency virus type 1 replication in vitro by a novel combination of anti-Tat single-chain intrabodies and NF-kappa B antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Potent inhibition of human immunodeficiency virus type 1 replication by an intracellular anti-Rev single-chain antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Binding of intracellular anti-Rev single chain variable fragments to different epitopes of human immunodeficiency virus type 1 rev: variations in viral inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intracellular immunization against HIV-1 infection of human T lymphocytes: utility of anti-rev single-chain variable fragments

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits reverse transcription and viral replication

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Targeted tumor killing via an intracellular antibody against erbB-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Antineoplastic effect of anti-erbB-2 intrabody is not correlated with scFv affinity for its target

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Transductional efficacy and safety of an intraperitoneally delivered adenovirus encoding an anti-erbB-2 intracellular single-chain antibody for ovarian cancer gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

1 reference

7 January 2021

Intracellular immunization. Cloning and intracellular expression of a monoclonal antibody to the p21ras protein

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intracellular single chain Fv antibody inhibits Ras activity in T-cell antigen receptor stimulated Jurkat cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intracellular expression of anti-p21ras single chain Fv fragments inhibits meiotic maturation of xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intracellular immunization with cytosolic recombinant antibodies.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

ras proteins can induce meiosis in Xenopus oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intracellular antibody-caspase-mediated cell killing: an approach for application in cancer therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Extended half-life and elevated steady-state level of a single-chain Fv intrabody are critical for specific intracellular retargeting of its antigen, caspase-7.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Live or let die: the cell's response to p53

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Characterization of a new intrabody directed against the N-terminal region of human p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Interleukin-2: inception, impact, and implications

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

The IL-2 receptor complex: its structure, function, and target genes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Transformation of human umbilical cord blood T cells by human T-cell leukemia/lymphoma virus

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Inducible knockout of the interleukin-2 receptor alpha chain: expression of the high-affinity IL-2 receptor is not required for the in vitro growth of HTLV-I-transformed cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intrabody-mediated knockout of the high-affinity IL-2 receptor in primary human T cells using a bicistronic lentivirus vector

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the alpha subunit of the receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

The use of intracellular single-chain antibody fragments to inhibit specifically the expression of cell surface molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Sequence and tissue distribution of the integrin alpha 9 subunit, a novel partner of beta 1 that is widely distributed in epithelia and muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

The pathophysiologic role of alpha 4 integrins in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intracellular single-chain antibody inhibits integrin VLA-4 maturation and function

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Characterization and binding of intracellular antibody fragments to the hepatitis C virus core protein

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intrabody-based strategies for inhibition of vascular endothelial growth factor receptor-2: effects on apoptosis, cell growth, and angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

The regulated expression of an intrabody produces a mutant phenotype in Drosophila.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Isolation and characterization of single-chain Fv genes encoding antibodies specific for Drosophila Poxn protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Synthesis of a functional anti-phytochrome single-chain Fv protein in transgenic tobacco

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

RNA interference--a new weapon against HIV and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

RNA interference: antiviral defense and genetic tool

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

The role of VEGF in normal and neoplastic hematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intracellular stability of anti-caspase-3 intrabodies determines efficacy in retargeting the antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Intrabodies based on intracellular capture frameworks that bind the RAS protein with high affinity and impair oncogenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Characterization of anti-cyclin E single-chain Fv antibodies and intrabodies in breast cancer cells: enhanced intracellular stability of novel sFv-F(c) intrabodies

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900183-7

7 January 2021

10.1016/S1525-0016(03)00183-7

Identifiers

DOI

1 reference

7 August 2017

1 reference

PubMed ID

12946308