(Q35213491)

7 August 2017

Targeted ablation, silencing, and activation establish glycinergic dorsal horn neurons as key components of a spinal gate for pain and itch (English)

1 reference

7 August 2017

Karl-Klaus Conzelmann

11

1 reference

7 August 2017

Hanns Ulrich Zeilhofer

13

object named as

Hanns Ulrich Zeilhofer

1 reference

7 August 2017

Edmund Foster

1

0 references

Alexander Ghanem

10

object named as

Alexander Ghanem

1 reference

7 August 2017

Hendrik Wildner

2

1 reference

7 August 2017

Laetitia Tudeau

3

1 reference

7 August 2017

Sabine Haueter

4

1 reference

7 August 2017

William T Ralvenius

5

1 reference

7 August 2017

Monika Jegen

6

1 reference

7 August 2017

Helge Johannssen

7

1 reference

7 August 2017

Ladina Hösli

8

1 reference

7 August 2017

Karen Haenraets

9

1 reference

7 August 2017

Michael Bösl

12

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 March 2015

1 reference

7 August 2017

1 reference

7 August 2017

85

1 reference

7 August 2017

6

1 reference

7 August 2017

1289-1304

1 reference

describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4372258/fullTextXML

inferred from PubMed Central ID database lookup

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13 July 2018

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A quantitative study of inhibitory interneurons in laminae I-III of the mouse spinal dorsal horn

13 July 2018

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Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain

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A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia

13 July 2018

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13 July 2018

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Forebrain GABAergic neuron precursors integrate into adult spinal cord and reduce injury-induced neuropathic pain

13 July 2018

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Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.

13 July 2018

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Fast synaptic inhibition in spinal sensory processing and pain control

13 July 2018

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Multiple mechanisms of microglia: a gatekeeper's contribution to pain states

13 July 2018

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How inhibition shapes cortical activity

13 July 2018

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Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function

13 July 2018

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Dynorphin is expressed primarily by GABAergic neurons that contain galanin in the rat dorsal horn

13 July 2018

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Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector

13 July 2018

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Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia.

13 July 2018

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Adeno-associated viral vectors for mapping, monitoring, and manipulating neural circuits

13 July 2018

1 reference

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Central mechanisms of pathological pain

13 July 2018

1 reference

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Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice.

13 July 2018

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Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors

13 July 2018

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Circuits controlling vertebrate locomotion: moving in a new direction

13 July 2018

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Relief of itch by scratching: state-dependent inhibition of primate spinothalamic tract neurons

13 July 2018

1 reference

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Models and mechanisms of hyperalgesia and allodynia

13 July 2018

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A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

13 July 2018

1 reference

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Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain

13 July 2018

1 reference

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Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

13 July 2018

1 reference

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Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Glycinergic neurons expressing enhanced green fluorescent protein in bacterial artificial chromosome transgenic mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization

13 July 2018

1 reference

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Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Neuronal plasticity: increasing the gain in pain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Generalized lacZ expression with the ROSA26 Cre reporter strain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Recombinant adeno-associated virus vector: use for transgene expression and anterograde tract tracing in the CNS

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

The glycine transporter GLYT2 is a reliable marker for glycine-immunoreactive neurons.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

A comparison of the effects of noxious and innocuous counterstimuli on experimentally induced itch and pain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Morphine insensitive allodynia is produced by intrathecal strychnine in the lightly anesthetized rat.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

The localization of classical transmitters and neuropeptides within neurons in laminae I-III of the mammalian spinal dorsal horn

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Pain mechanisms: a new theory

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Glycine inhibitory dysfunction induces a selectively dynamic, morphine-resistant, and neurokinin 1 receptor- independent mechanical allodynia.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Reversal of pathological pain through specific spinal GABAA receptor subtypes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Distribution of glycinergic neuronal somata in the rat spinal cord.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Disinhibition opens the gate to pathological pain signaling in superficial neurokinin 1 receptor-expressing neurons in rat spinal cord.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Mechanical allodynia following contusion injury of the rat spinal cord is associated with loss of GABAergic inhibition in the dorsal horn

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Reduction of glycine receptor-mediated miniature inhibitory postsynaptic currents in rat spinal lamina I neurons after peripheral inflammation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

PGE(2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Region-specific developmental specialization of GABA-glycine cosynapses in laminas I-II of the rat spinal dorsal horn.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Coadministration of intrathecal strychnine and bicuculline effects synergistic allodynia in the rat: an isobolographic analysis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

The contribution of GABAA and glycine receptors to central sensitization: disinhibition and touch-evoked allodynia in the spinal cord.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Subpopulations of GABAergic neurons in laminae I-III of rat spinal dorsal horn defined by coexistence with classical transmitters, peptides, nitric oxide synthase or parvalbumin.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Role of spinal microglia in rat models of peripheral nerve injury and inflammation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4372258

Hyperalgesia induced by altered glycinergic activity at the spinal cord

15 November 2018

1 reference

12 December 2020

Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene

1 reference

12 December 2020

Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists

1 reference

12 December 2020

Galanin is contained in GABAergic neurons in the rat spinal dorsal horn

1 reference

12 December 2020

10.1016/J.NEURON.2015.02.028

Identifiers

DOI

1 reference

7 August 2017

1 reference

7 August 2017

1 reference