(Q35216446)

7 August 2017

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title

The distinct role of mGlu1 receptors in post-ischemic neuronal death (English)

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7 August 2017

author name string

Domenico E Pellegrini-Giampietro

series ordinal

1

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7 August 2017

publication date

1 September 2003

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Trends in Pharmacological Sciences

7 August 2017

published in

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7 August 2017

volume

24

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7 August 2017

issue

9

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7 August 2017

page(s)

461-470

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Molecular determinants of metabotropic glutamate receptor signaling.

7 August 2017

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Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus

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Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs

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Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

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Group I metabotropic glutamate receptors: implications for brain diseases

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Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

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7 January 2021

Distinct physiological roles of the Gq-coupled metabotropic glutamate receptors Co-expressed in the same neuronal populations

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7 January 2021

Complex interactions between mGluRs, intracellular Ca2+ stores and ion channels in neurons

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7 January 2021

Antagonists for group I mGluRs attenuate excitotoxic neuronal death in cortical cultures

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The changing landscape of ischaemic brain injury mechanisms.

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Reversal of glutamate excitotoxicity by activation of PKC-associated metabotropic glutamate receptors in cerebellar granule cells relies on NR2C subunit expression.

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7 January 2021

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

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7 January 2021

An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors

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7 January 2021

Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 r

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7 January 2021

Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission

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7 January 2021

The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity

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7 January 2021

The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death

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7 January 2021

1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia

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7 January 2021

Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro

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7 January 2021

Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo

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7 January 2021

The novel and systemically active metabotropic glutamate 1 (mGlu1) receptor antagonist 3-MATIDA reduces post-ischemic neuronal death

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7 January 2021

Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: time-course and mechanisms

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7 January 2021

The mGlu receptor ligand (S)-4C3HPG protects neurons after global ischaemia in gerbils

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7 January 2021

(S)-4C3HPG reduces infarct size after focal cerebral ischemia.

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7 January 2021

Neuroprotective and behavioral effects of the selective metabotropic glutamate mGlu(1) receptor antagonist BAY 36-7620.

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7 January 2021

Coordinate regulation of metabotropic glutamate receptors

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7 January 2021

Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective

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7 January 2021

Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil

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7 January 2021

Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia

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7 January 2021

Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

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7 January 2021

Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors

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Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function.

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7 January 2021

Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus.

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7 January 2021

Haloperidol-induced alteration in the physiological actions of group I mGlus in the subthalamic nucleus and the substantia nigra pars reticulata

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7 January 2021

Selective involvement of mGlu1 receptors in corticostriatal LTD.

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7 January 2021

Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

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7 January 2021

Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons.

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7 January 2021

Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury.

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7 January 2021

Selective blockade of the mGluR1 receptor reduces traumatic neuronal injury in vitro and improvesoOutcome after brain trauma

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7 January 2021

Group I metabotropic glutamate antagonist reduces acute neuronal degeneration and behavioral deficits after traumatic brain injury in rats.

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7 January 2021

Role of Group I Metabotropic Glutamate Receptors in Traumatic Spinal Cord White Matter Injury

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7 January 2021

Group I metabotropic glutamate receptors in spinal cord injury: roles in neuroprotection and the development of chronic central pain

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7 January 2021

Anticonvulsant activity of two metabotropic glutamate group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)-pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893).

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7 January 2021

Differential roles for mGluR1 and mGluR5 in the persistent prolongation of epileptiform bursts

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7 January 2021

Metabotropic glutamate 1 (mGlu1) receptor antagonists enhance GABAergic neurotransmission: a mechanism for the attenuation of post-ischemic injury and epileptiform activity?

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7 January 2021

Beta-amyloid-induced apoptosis of cerebellar granule cells and cortical neurons: exacerbation by selective inhibition of group I metabotropic glutamate receptors

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7 January 2021

Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity.

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7 January 2021

Exacerbation of neuronal cell death by activation of group I metabotropic glutamate receptors: role of NMDA receptors and arachidonic acid release.

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7 January 2021

Interactions between ionotropic and metabotropic glutamate receptors regulate cAMP response element-binding protein phosphorylation in cultured striatal neurons

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7 January 2021

Increased expression of neuronal nitric oxide synthase spliced variants in reactive astrocytes of amyotrophic lateral sclerosis human spinal cord

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7 January 2021

The metabotropic glutamate receptor mGlu5 controls the onset of developmental apoptosis in cultured cerebellar neurons

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7 January 2021

Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders

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7 January 2021

The metabotropic glutamate receptor (mGluR1 alpha) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction.

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7 January 2021

Synaptic input of horizontal interneurons in stratum oriens of the hippocampal CA1 subfield: structural basis of feed-back activation

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7 January 2021

Immunolocalization of mGluR1alpha in specific populations of local circuit neurons in the cerebral cortex

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7 January 2021

Localization of mGluR1a-like immunoreactivity and mGluR5-like immunoreactivity in identified populations of striatal neurons

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7 January 2021

Activation of group I metabotropic glutamate receptors produces a direct excitation and disinhibition of GABAergic projection neurons in the substantia nigra pars reticulata.

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7 January 2021

Evidence for metabotropic glutamate receptor activation in the induction of depolarization-induced suppression of inhibition in hippocampal CA1.

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7 January 2021

gamma-Aminobutyric acid(A) neurotransmission and cerebral ischemia

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7 January 2021

Differential subcellular localization of mGluR1a and mGluR5 in the rat and monkey Substantia nigra.

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7 January 2021

Presynaptic group 1 metabotropic glutamate receptors may contribute to the expression of long-term potentiation in the hippocampal CA1 region

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7 January 2021

Presynaptic mGlu1 type receptors potentiate transmitter output in the rat cortex

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7 January 2021

Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons

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7 January 2021

Rat group I metabotropic glutamate receptors inhibit neuronal Ca2+ channels via multiple signal transduction pathways in HEK 293 cells.

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7 January 2021

Glutamate mediates an inhibitory postsynaptic potential in dopamine neurons

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7 January 2021

Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons.

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7 January 2021

Differential expression of rat and human type I metabotropic glutamate receptor splice variant messenger RNAs

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7 January 2021

Immunohistochemical localization of the mGluR1? metabotropic glutamate receptor in the adult rodent forebrain: Evidence for a differential distribution of mGluR1 splice variants

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7 January 2021

Metabotropic glutamate receptors drive the endocannabinoid system in hippocampus.

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7 January 2021

Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors

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7 January 2021

Retrograde signaling in the regulation of synaptic transmission: focus on endocannabinoids

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7 January 2021

Short-term retrograde inhibition of GABAergic synaptic currents in rat Purkinje cells is mediated by endogenous cannabinoids.

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7 January 2021

Postsynaptic endocannabinoid release is critical to long-term depression in the striatum

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7 January 2021

Heterosynaptic LTD of hippocampal GABAergic synapses: a novel role of endocannabinoids in regulating excitability

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7 January 2021

Kainate receptor modulation of GABA release involves a metabotropic function

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7 January 2021

Paraneoplastic cerebellar ataxia due to autoantibodies against a glutamate receptor

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7 January 2021

Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site

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7 January 2021

Synthesis and biological evaluation of 2-(3'-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist

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7 January 2021

BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse agonist activity

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7 January 2021

Mutational analysis and molecular modeling of the allosteric binding site of a novel, selective, noncompetitive antagonist of the metabotropic glutamate 1 receptor

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7 January 2021

Synthesis and pharmacological characterisation of 2,4-dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists

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7 January 2021

A novel, competitive mGlu(5) receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices

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7 January 2021

Reduced stress-induced hyperthermia in mGluR5 knockout mice

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7 January 2021

Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS

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7 January 2021

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Identifiers

DOI

1 reference

7 August 2017

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