(Q35219000)

7 August 2017

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title

Molecular and functional interdependence of the urokinase-type plasminogen activator system with integrins (English)

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7 August 2017

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Ute Reuning

1

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7 August 2017

Viktor Magdolen

series ordinal

2

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7 August 2017

Sandra Hapke

series ordinal

3

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7 August 2017

Manfred Schmitt

series ordinal

4

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7 August 2017

publication date

1 August 2003

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7 August 2017

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7 August 2017

volume

384

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7 August 2017

issue

8

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7 August 2017

page(s)

1119-1131

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Down-regulation of integrin alpha(v)beta(3) expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense urokinase-type plasminogen activator receptor (uPAR) and sense p16 genes.

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Overexpression of alpha(v)beta6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Induction of Apoptosis in Vascular Cells by Plasminogen Activator Inhibitor-1 and High Molecular Weight Kininogen Correlates with Their Anti-Adhesive Properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

The plasminogen activation system in tumor growth, invasion, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

uPAR: a versatile signalling orchestrator

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Haemostatic factors occupy new territory: the role of the urokinase receptor system and kininogen in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase-urokinase receptor interaction: non-mitogenic signal transduction in human epidermal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Plasminogen activator inhibitor-1 regulates cell adhesion by binding to the somatomedin B domain of vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Interaction of urokinase with specific receptors stimulates mobilization of bovine adrenal capillary endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase induces proliferation of human ovarian cancer cells: characterization of structural elements required for growth factor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Kinetic analysis of integrin-dependent cell adhesion on vitronectin--the inhibitory potential of plasminogen activator inhibitor-1 and RGD peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Integrin alpha(v)beta(3)/vitronectin interaction affects expression of the urokinase system in human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

beta(3)A-integrin downregulates the urokinase-type plasminogen activator receptor (u-PAR) through a PEA3/ets transcriptional silencing element in the u-PAR promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

A reevaluation of integrins as regulators of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

The plasminogen activator system: biology and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Collagen modulates gene activation of plasminogen activator system molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Regulation of urokinase plasminogen activator/plasmin-mediated invasion of melanoma cells by the integrin vitronectin receptor alphaVbeta3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Growth stimulation of human epidermal cells by urokinase is restricted to the intact active enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Plasminogen activator inhibitor-1 represses integrin- and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Cell adhesion regulates the plasminogen activator inhibitor-1 gene expression in anchorage-dependent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Systematic mutational analysis of the receptor-binding region of the human urokinase-type plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Coordinated expression of the vitronectin receptor and the urokinase-type plasminogen activator receptor in metastatic melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Kinetic analysis of the interaction between vitronectin and the urokinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin alpha Mbeta 2 as well as by the urokinase receptor regulates cell adhesion and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Rel transcription factors contribute to elevated urokinase expression in human ovarian carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin (Vn): mapping the binding sites on PAI-1 and Vn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Integrin signaling revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Engaged urokinase receptors enhance tumor breast cell migration and invasion by upregulating alpha(v)beta5 vitronectin receptor cell surface expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Identification of a urokinase receptor-integrin interaction site. Promiscuous regulator of integrin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase-dependent human vascular smooth muscle cell adhesion requires selective vitronectin phosphorylation by ectoprotein kinase CK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Soluble urokinase receptor promotes cell adhesion and requires tyrosine-92 for activation of p56/59(hck).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Involvement of fibronectin in the regulation of urokinase production and binding in murine mammary tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase-receptor/integrin complexes are functionally involved in adhesion and progression of human breast cancer in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Regulation of integrin function by the urokinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

Cloning, expression and mapping of a novel human zinc-finger gene TCF17 homologous to rodent Kid1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2003.125

21 January 2018

Identifiers

DOI

10.1515/BC.2003.125

1 reference

7 August 2017

1 reference