(Q35221856)

English

Disabled-2 heterozygous mice are predisposed to endometrial and ovarian tumorigenesis and exhibit sex-biased embryonic lethality in a p53-null background

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

Disabled-2 heterozygous mice are predisposed to endometrial and ovarian tumorigenesis and exhibit sex-biased embryonic lethality in a p53-null background (English)

1 reference

Europe PubMed Central

7 August 2017

0 references

1 reference

based on heuristic

inferred from title

Cynthia B Cohen

6

object named as

Cynthia Cohen

1 reference

Europe PubMed Central

7 August 2017

author name string

Dong-Hua Yang

1

1 reference

Europe PubMed Central

7 August 2017

Zia Fazili

2

1 reference

Europe PubMed Central

7 August 2017

Elizabeth R Smith

3

1 reference

Europe PubMed Central

7 August 2017

Kathy Qi Cai

4

1 reference

Europe PubMed Central

7 August 2017

Andres Klein-Szanto

5

1 reference

Europe PubMed Central

7 August 2017

Ira R Horowitz

7

1 reference

Europe PubMed Central

7 August 2017

Xiang-Xi Xu

8

1 reference

Europe PubMed Central

7 August 2017

language of work or name

0 references

publication date

1 July 2006

1 reference

Europe PubMed Central

7 August 2017

The American Journal of Pathology

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Europe PubMed Central

7 August 2017

169

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Europe PubMed Central

7 August 2017

1

1 reference

Europe PubMed Central

7 August 2017

258-267

1 reference

Europe PubMed Central

7 August 2017

Disabled-2 (Dab2) mediates transforming growth factor beta (TGFbeta)-stimulated fibronectin synthesis through TGFbeta-activated kinase 1 and activation of the JNK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Origins and molecular pathology of ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

LKB1 tumor suppressor protein: PARtaker in cell polarity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Molecular events associated with dysplastic morphologic transformation and initiation of ovarian tumorigenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Conditional mouse models of sporadic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

DOC-2/DAB2 is the binding partner of myosin VI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Disabled-2 mediates c-Fos suppression and the cell growth regulatory activity of retinoic acid in embryonic carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

The inhibitory role of DOC-2/DAB2 in growth factor receptor-mediated signal cascade. DOC-2/DAB2-mediated inhibition of ERK phosphorylation via binding to Grb2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Precursor lesions of ovarian epithelial malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Restoration of positioning control following Disabled-2 expression in ovarian and breast tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Disabled-2 inactivation is an early step in ovarian tumorigenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

DOC-2/hDab2, a candidate tumor suppressor gene involved in the development of gestational trophoblastic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Regulation of rat DOC-2 gene during castration-induced rat ventral prostate degeneration and its growth inhibitory function in human prostatic carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Female embryonic lethality in mice nullizygous for both Msh2 and p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Pathology of ovarian cancer precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Molecular basis of endometrial cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Molecular cloning of differentially expressed genes in human epithelial ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

The p53 tumor suppressor gene frequently is altered in gynecologic cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Tumor spectrum analysis in p53-mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

The nature of cancer: morphogenesis and progressive (self)-disorganization in neoplastic development and progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

13 July 2018

Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

26 September 2018

Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

26 September 2018

High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

24 October 2018

Early form of ovarian cancer originating in inclusion cysts. A case report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698752

24 October 2018

Disabled-2 exerts its tumor suppressor activity by uncoupling c-Fos expression and MAP kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16816378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p96, a MAPK-related protein, is consistently downregulated during mouse mammary carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16816378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focus on epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16816378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor formation in p53 mutant ovaries transplanted into wild-type female hosts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16816378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphologic precursors of ovarian epithelial tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16816378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2006.060036

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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0 references

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