(Q35222288)

7 August 2017

title

Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells (English)

1 reference

7 August 2017

1 reference

Zhong-Wei Du

1

1 reference

7 August 2017

Hong Chen

2

1 reference

7 August 2017

Huisheng Liu

3

1 reference

7 August 2017

Jianfeng Lu

4

1 reference

7 August 2017

Kun Qian

5

1 reference

7 August 2017

CindyTzu-Ling Huang

6

1 reference

7 August 2017

Xiaofen Zhong

7

1 reference

7 August 2017

Frank Fan

8

1 reference

7 August 2017

Su-Chun Zhang

9

1 reference

7 August 2017

language of work or name

English

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publication date

25 March 2015

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7 August 2017

published in

Nature Communications

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7 August 2017

volume

6

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7 August 2017

page(s)

6626

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Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons

7 August 2017

cites work

1 reference

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Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.

27 July 2018

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High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1.

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Generation of integration-free and region-specific neural progenitors from primate fibroblasts

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Accelerated high-yield generation of limb-innervating motor neurons from human stem cells

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Glial progenitor cell-based treatment and modeling of neurological disease

27 July 2018

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EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

27 July 2018

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DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction.

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Drug screening for ALS using patient-specific induced pluripotent stem cells

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Specification of midbrain dopamine neurons from primate pluripotent stem cells

27 July 2018

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Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

27 July 2018

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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Specification of neuronal and glial subtypes from human pluripotent stem cells

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS.

27 July 2018

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Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes.

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Constructing and deconstructing stem cell models of neurological disease

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

27 July 2018

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Induced pluripotent stem cells from a spinal muscular atrophy patient

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Directed differentiation of embryonic stem cells into motor neurons

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Transcriptional networks regulating neuronal identity in the developing spinal cord

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axons

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.

26 September 2018

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Induced pluripotent stem cells--opportunities for disease modelling and drug discovery

26 September 2018

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A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy

26 September 2018

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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

26 September 2018

1 reference

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Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells.

26 September 2018

1 reference

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Specification of motoneurons from human embryonic stem cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Notch signalling and the control of cell fate choices in vertebrates.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375778

Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors

26 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7626

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7626

A simple and efficient system for regulating gene expression in human pluripotent stem cells and derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7626

Specification of transplantable astroglial subtypes from human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7626

21 January 2018

Identifiers

DOI

10.1038/NCOMMS7626

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference